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Molecular development

Distinct Functional Patterns of Gene Promoter Hypomethylation and Hypermethylation in Cancer Genomes

Xiaopei Shen, Zheng He, Hongdong Li, Chen Yao, Yang Zhang, Lang He, Shan Li, Jian Huang, Zheng Guo

published 07 Sep 2012

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Vascular Dysfunction following Polymicrobial Sepsis: Role of Pattern Recognition Receptors

Stefan Felix Ehrentraut, Anne Dörr, Heidi Ehrentraut, Ralph Lohner, Sun-Hee Lee, Andreas Hoeft, Georg Baumgarten, Pascal Knuefermann, Olaf Boehm, Rainer Meyer

published 07 Sep 2012

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Human Cytomegalovirus Induces TLR4 Signaling Components in Monocytes Altering TIRAP, TRAM and Downstream Interferon-Beta and TNF-Alpha Expression

Kok-Hooi Yew, Cory Carpenter, R. Scott Duncan, Christopher J. Harrison

published 07 Sep 2012

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n-Butylidenephthalide (BP) Maintains Stem Cell Pluripotency by Activating Jak2/Stat3 Pathway and Increases the Efficiency of iPS Cells Generation

Shih-Ping Liu, Horng-Jyh Harn, Ying-Jiun Chien, Cheng-Hsuan Chang, Chien-Yu Hsu, Ru-Huei Fu, Yu-Chuen Huang, Shih-Yin Chen, Woei-Cherng Shyu, Shinn-Zong Lin

published 07 Sep 2012

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Bone Marrow-Derived Mesenchymal Stem Cells Repaired but Did Not Prevent Gentamicin-Induced Acute Kidney Injury through Paracrine Effects in Rats

Luciana A. Reis, Fernanda T. Borges, Manuel J. Simões, Andrea A. Borges, Rita Sinigaglia-Coimbra, Nestor Schor

published 06 Sep 2012

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Safety and Tolerability of Lactobacillus reuteri DSM 17938 and Effects on Biomarkers in Healthy Adults: Results from a Randomized Masked Trial

Nisha Mangalat, Yuying Liu, Nicole Y. Fatheree, Michael J. Ferris, Melissa R. Van Arsdall, Zhongxue Chen, Mohammad H. Rahbar, Wallace A. Gleason, Johana Norori, Dat Q. Tran, J. Marc Rhoads

published 06 Sep 2012

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A Neonatal Model of Intravenous Staphylococcus epidermidis Infection in Mice <24 h Old Enables Characterization of Early Innate Immune Responses

Kenny D. Kronforst, Christy J. Mancuso, Matthew Pettengill, Jana Ninkovic, Melanie R. Power Coombs, Chad Stevens, Michael Otto, Carina Mallard, Xiaoyang Wang, Donald Goldmann, Ofer Levy

published 06 Sep 2012

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Optimal Isolation of Functional Foxp3⁺ Induced Regulatory T Cells Using DEREG Mice

Abdul Mannan Baru, Christopher Untucht, Venkateswaran Ganesh, Christina Hesse, Christian T. Mayer, Tim Sparwasser

published 05 Sep 2012

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Graft versus Host Disease in the Bone Marrow, Liver and Thymus Humanized Mouse Model

Matthew B. Greenblatt, Vladimir Vbranac, Trevor Tivey, Kelly Tsang, Andrew M. Tager, Antonios O. Aliprantis

published 05 Sep 2012

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Kinetics of T Helper Subsets and Associated Cytokines Correlate Well with the Clinical Activity of Graft-Versus-Host Disease

Su-Peng Yeh, Yu-Min Liao, Wen-Jyi Lo, Chiao-Lin Lin, Li-Yuan Bai, Chen-Yuan Lin, Ching-Yun Hsieh, Yu-Chien Chang, Yu-Ting Huang, Chang-Fang Chiu

published 05 Sep 2012

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Meta-Analysis Derived (MAD) Transcriptome of Psoriasis Defines the “Core” Pathogenesis of Disease

Suyan Tian, James G. Krueger, Katherine Li, Ali Jabbari, Carrie Brodmerkel, Michelle A. Lowes, Mayte Suárez-Fariñas

published 05 Sep 2012

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Short-Term Erythropoietin Treatment Does Not Substantially Modulate Monocyte Transcriptomes of Patients with Combined Heart and Renal Failure

Kim E. Jie, Karien van der Putten, Sebastiaan Wesseling, Jaap A. Joles, Marloes W. Bergevoet, Floor Pepers-de Kort, Pieter A. Doevendans, Yutaka Yasui, Qi Liu, Marianne C. Verhaar, Carlo A. Gaillard, Branko Braam

published 05 Sep 2012

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Early Vascular Alterations in SLE and RA Patients—A Step towards Understanding the Associated Cardiovascular Risk

Maria José Santos, Diana Carmona-Fernandes, Helena Canhão, José Canas da Silva, João Eurico Fonseca, Victor Gil

published 04 Sep 2012

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