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Molecular development

Anti-inflammatory activity of Acanthospermum australe: Insights from network pharmacology, chemical analysis, and in vitro assays

Andrea Salinas, Christa Burgos, Aaron Rodríguez-Ramos, Alberto Burgos-Edwards, Nelson Alvarenga, Pablo H. Sotelo, Patricia Langjahr

published 26 Nov 2025

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TNFAIP3 alleviates cerebral ischemia-reperfusion injury by inhibiting M1 microglia polarization via deubiquitination of RACK1

Wenya Bai, Shixuan Liu, Guilin Zhou, Xuelian Li, Huan Jiang, Jianlin Shao, Junchao Zhu

published 26 Nov 2025

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The effect of therapeutic potential and safety of bone marrow-derived against adipose-derived mesenchymal stem cells in aged mice associated with septic arthritis

Alani Mohanad Khalid Ahmed, Mujahid Khalaf Ali, Basma Kh. Alani

published 26 Nov 2025

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Dogs with advanced myxomatous mitral valve disease have evidence of gastrointestinal bacterial translocation and systemic inflammation

Maria C. Jugan, Gabrielle A. Rands, Joerg M. Steiner, Natalia Cernicchiaro, Matthew C. Tanner, Lillian M. Novotny

published 24 Nov 2025

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BCG cell wall skeleton augments the immunogenicity of dengue nanoparticle vaccines by promoting dendritic cell activation

Jitra Limthongkul, Saradee Warit, Panya Sunintaboon, Sukathida Ubol, Tuksin Jearanaiwitayakul

published 20 Nov 2025

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TSLPR deficiency attenuates AHR independently of eosinophilia and mucus secretion in a chronic HDM mouse model of allergic asthma

Latifa Koussih, Sina Taefehshokr, Lianyu Shan, Sujata Basu, Andrew Halayko, Bouchaib Lamkhioued, Abdelilah S. Gounni

published 19 Nov 2025

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Influence of serum adiponectin on baseline albuminuria and subsequent decline in eGFR in African Americans: The Jackson Heart Study

Mohit Agarwal, Prakrati C. Acharya, Aditi Kumar, Norah Sohail, Luis A. Juncos, Bessie A. Young

published 18 Nov 2025

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Combined benznidazole and pentoxifylline therapy improves behavioral and cognitive changes in association with the regulation of systemic inflammatory profile in chronic experimental Chagas disease

Glaucia Vilar-Pereira, Leda Margarita Castaño-Barrios, Isabela Resende Pereira, Ana Paula da Silva Pinheiro, Thayse do Espírito Santo Protásio da Silva, Lina L. Hernandez-Velasco, Priscila Silva Grijó Farani, Aditi Kulkarni, Sourav Roy, Hílton Antônio Mata dos Santos, Raquel de Oliveira Lopes, Luzineide Wanderley Tinoco, Constança Britto, Otacílio Cruz Moreira, Andrea Alice Silva, Joseli Lannes-Vieira

published 14 Nov 2025

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High fructose corn syrup ınduced liver and heart damage are not reversed with hazelnut consumption: In vivo study

Ayça Toprak-Semiz, Efsane Yavuz-Bedir, Hakan Yüzüak, Murat Usta, Demet Şengül

published 07 Nov 2025

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Sleep deprivation disrupts diurnal rhythmicity of gut microbiota and blood inflammatory cytokines in mice

Weiran Shan, Wenzhe Zang, Zhiyi Zuo

published 07 Nov 2025

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Optimizing the in vitro production of immunomodulatory cells for the induction of tolerance in solid organ transplantation

Nils Ågren, Ming Yao, Carl Skantze, Keyvan Habibi, Bo-Göran Ericzon, Makiko Kumagai-Braesch

published 07 Nov 2025

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Exploration of key markers driving ferroptosis in the progression of non-alcoholic fatty liver disease

Jiyong Zhang, Weiyan Li, Xiaoying Qiu, Yuanyuan Wang, Yongmei Zeng

published 07 Nov 2025

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Xiao Qing Long Tang ameliorates neutrophil extracellular trap-dendritic cells-T helper 17 cell axis in Neutrophilic Asthma

Xiaoying Ji, Hongda Chen, Sheng-dong He, Min Huang, Xiaoli You, Chuan Xiao, Zhifeng Chen, Jinwen Cai

published 06 Nov 2025

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