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Molecular development

TLR9/MyD88/NF-κB signaling mediates mental stress-induced exacerbation of psoriasis through immune dysregulation in a mouse model

Qiuhe Song, Dongyang Li, Zhihao Yuan, Chaowen Zhang, Jianqiao Wang, Fangfang Liao, Pengfei Xu, Qipeng Xiao

published 06 Mar 2026

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Huanggan decoction ameliorates cholestatic hepatic fibrosis in rats via TGF-β1/Smad3 signaling pathway

Yaya Lei, Xueli Ma, Xiaohui Jin, Yanping He, Jianhong Yang, Yuna Zhao, Jing Chen, Ting Gao

published 04 Mar 2026

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Constitutive activation of TGF-β receptor type I promotes cortical and cancellous bone formation in adult mice

Tipthanan Chotipinit, Parichart Toejing, Chinnatam Phetkong, Somyoth Sridurongrit, Asada Leelahavanichkul, Julia F. Charles, Sutada Lotinun

published 02 Mar 2026

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Attenuating effects of inflammatory pathway by prolonged left ventricular unloading after myocardial infarction in male rats

Jingwen Gao, Yasushige Shingu, Ryota Azuma, Satoru Wakasa

published 26 Feb 2026

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Anti-inflammatory activity and metabolite profiling of myo-inositol in LPS-stimulated macrophages

Marwa Seif, Lina Dahabiyeh, Afnan Al‐Hunaiti, Mohammad Semreen, Malek Zihlif, Hamzeh Al-Ameer, Amer Imraish

published 25 Feb 2026

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TL1A serves as a positive regulator to promote adipocyte differentiation

Ziqi Chang, Qiaoyu Wang, Yan Zhai, Ke Li, Xianjie Zheng, Yaohui Wang, Dan Zhao

published 19 Feb 2026

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Longitudinal changes in circulating biomarkers from baseline to week 48 in treatment-Naïve people living with HIV initiating integrase inhibitor-based antiretroviral therapy

Jose-Ramon Blanco, Miguel Torralba, María Saumoy, Antonia Alcaraz, Mariano Matarranz del Amo, Julian Olalla, Fernando Dronda, Nisa Boukichou-Abdelkader, Enrique Bernal, Sergio Padilla, Joaquim Peraire, Francisca Artigues, María-Jesús Bustinduy-Odriozola, Helena Albendin Iglesias, Alberto Delgado, Arkaitz Imaz, Laura Pérez-Martinez, CoR.I.S. Cohort

published 18 Feb 2026

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The JAK1-STAT1 signaling pathway triggers inflammation responses in chronic obstructive sleep apnea rat model

Lin Yang, Jie He

published 17 Feb 2026

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A VPS33B CRISPR knockout study: In vitro evidence of an adhesion defect

Maria Caluianu, Kimberley A. Owen

published 13 Feb 2026

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Expression of aqueous cytokines and their correlation with retinal morphological biomarkers in nAMD patients

Jingxin Zeng, Wenwen Shang, Pengfei Ren, Xiao Ke, Yonghao Zhao, Guina Liu, Jie Liu, Fang Lu, Xiaoshuang Jiang

published 11 Feb 2026

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Postpartum cytokine shifts and IL-10–mediated immune suppression in malaria-infected primigravid women

Ousmane Traore, Toussaint Rouamba, Serge Henri Zango, Hermann Sorgho, Innocent Valea, Maminata Traore-Coulibaly, Henk D. F. H. Schallig, Halidou Tinto

published 10 Feb 2026

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Pulmonary fibroblasts activated by the addition of TNF-α and IL-4 enhance lymphangiogenic capacity and ameliorate lung fibrosis in an allogeneic rat model

Yuimi Matsuoka, Yuuki Shimizu, Koji Sakamoto, Makoto Matsuyama, Toyoaki Murohara, Takahiro Iwamiya

published 10 Feb 2026

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Broad immunogenicity of house dust mite proteins contrasts restricted specific IgE and IgG4 associated with allergy

Lars Harder Christensen, Jens Emil Vang Petersen, Gitte Lund, Jens Holm, Peter Adler Würtzen, Jakob Wiborg, Henrik Ipsen, Niels Johansen, Thomas Stranzl, Peter Sejer Andersen

published 09 Feb 2026

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