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Molecular development

Obesity Impairs γδ T Cell Homeostasis and Antiviral Function in Humans

Anne E. Costanzo, Kristen R. Taylor, Shelley Dutt, Peggy P. Han, Ken Fujioka, Julie M. Jameson

published 18 Mar 2015

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A Single Naturally Occurring 2’-O-Methylation Converts a TLR7- and TLR8-Activating RNA into a TLR8-Specific Ligand

Stephanie Jung, Tina von Thülen, Viktoria Laukemper, Stephanie Pigisch, Doris Hangel, Hermann Wagner, Andreas Kaufmann, Stefan Bauer

published 18 Mar 2015

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Combined Antigen-Specific Interferon-γ and Interleukin-2 Release Assay (FluoroSpot) for the Diagnosis of Mycobacterium tuberculosis Infection

Dumitru Chesov, Christoph Lange, Franziska Daduna, Valeriu Crudu, Rosemarie Preyer, Martin Ernst, Barbara Kalsdorf

published 18 Mar 2015

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Endothelial Nitric Oxide Synthase Deficient Mice Are Protected from Lipopolysaccharide Induced Acute Lung Injury

Christine M. Gross, Ruslan Rafikov, Sanjiv Kumar, Saurabh Aggarwal, P. Benson Ham III, Mary Louise Meadows, Mary Cherian-Shaw, Archana Kangath, Supriya Sridhar, Rudolf Lucas, Stephen M. Black

published 18 Mar 2015

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Involvement of Neutrophil Hyporesponse and the Role of Toll-Like Receptors in Human Immunodeficiency Virus 1 Protection

Juan C. Hernandez, Diana M. Giraldo, Stephane Paul, Silvio Urcuqui-Inchima

published 18 Mar 2015

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Myocardial Mitochondrial and Contractile Function Are Preserved in Mice Lacking Adiponectin

Martin Braun, Niko Hettinger, Christoph Koentges, Katharina Pfeil, Maria C. Cimolai, Michael M. Hoffmann, Moritz Osterholt, Torsten Doenst, Christoph Bode, Heiko Bugger

published 18 Mar 2015

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Comparative Genomic Analysis of Buffalo (Bubalus bubalis) NOD1 and NOD2 Receptors and Their Functional Role in In-Vitro Cellular Immune Response

Biswajit Brahma, Sushil Kumar, Bidhan Chandra De, Purusottam Mishra, Mahesh Chandra Patra, Deepak Gaur, Meenu Chopra, Devika Gautam, Sourav Mahanty, Hrudananda Malik, Dhruba Malakar, Tirtha Kumar Datta, Sachinandan De

published 18 Mar 2015

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Mechanisms of Immunity in Post-Exposure Vaccination against Ebola Virus Infection

Steven B. Bradfute, Scott M. Anthony, Kelly S. Stuthman, Natarajan Ayithan, Prafullakumar Tailor, Carl I. Shaia, Mike Bray, Keiko Ozato, Sina Bavari

published 18 Mar 2015

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Methyl-Hydroxylamine as an Efficacious Antibacterial Agent That Targets the Ribonucleotide Reductase Enzyme

Esther Julián, Aida Baelo, Joan Gavaldà, Eduard Torrents

published 17 Mar 2015

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Inflammatory Cytokines in General and Central Obesity and Modulating Effects of Physical Activity

Frank M. Schmidt, Julia Weschenfelder, Christian Sander, Juliane Minkwitz, Julia Thormann, Tobias Chittka, Roland Mergl, Kenneth C. Kirkby, Mathias Faßhauer, Michael Stumvoll, Lesca M. Holdt, Daniel Teupser, Ulrich Hegerl, Hubertus Himmerich

published 17 Mar 2015

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Estrogens Induce Rapid Cytoskeleton Re-Organization in Human Dermal Fibroblasts via the Non-Classical Receptor GPR30

Julie Carnesecchi, Marilyne Malbouyres, Richard de Mets, Martial Balland, Gallic Beauchef, Katell Vié, Christophe Chamot, Claire Lionnet, Florence Ruggiero, Jean-Marc Vanacker

published 17 Mar 2015

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Tumor Progression Locus 2 Differentially Regulates IFNγ and IL-17 Production by Effector CD4⁺ T Cells in a T Cell Transfer Model of Colitis

Nicole V. Acuff, Xin Li, Rebecca Kirkland, Tamas Nagy, Wendy T. Watford

published 17 Mar 2015

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Co-Infection with Mycobacterium tuberculosis Impairs HIV-Specific CD8+ and CD4+ T Cell Functionality

Shivan Chetty, Pamla Govender, Jennifer Zupkosky, Mona Pillay, Musie Ghebremichael, Mahomed-Yunus S. Moosa, Thumbi Ndung’u, Filippos Porichis, Victoria O. Kasprowicz

published 17 Mar 2015

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