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Molecular development

Dysregulated Immune Activation in Second-Line HAART HIV+ Patients Is Similar to That of Untreated Patients

Milena S. Espíndola, Leonardo J. G. Lima, Luana S. Soares, Maira C. Cacemiro, Fabiana A. Zambuzi, Matheus de Souza Gomes, Laurence R. Amaral, Valdes R. Bollela, Olindo A. Martins-Filho, Fabiani G. Frantz

published 18 Dec 2015

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Protumoral TSP50 Regulates Macrophage Activities and Polarization via Production of TNF-α and IL-1β, and Activation of the NF-κB Signaling Pathway

Cheng Yang, Dong-Mei Zhang, Zhen-Bo Song, Ya-Qin Hou, Yong-Li Bao, Lu-Guo Sun, Chun-Lei Yu, Yu-Xin Li

published 18 Dec 2015

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Milk Leptin Surge and Biological Rhythms of Leptin and Other Regulatory Proteins in Breastmilk

Yuriy Nozhenko, Madhu Asnani-Kishnani, Ana M. Rodríguez, Andreu Palou

published 17 Dec 2015

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Selective Loss of Early Differentiated, Highly Functional PD1^high CD4 T Cells with HIV Progression

Robert M. Paris, Constantinos Petrovas, Sara Ferrando-Martinez, Eirini Moysi, Kristin L. Boswell, Eva Archer, Takuya Yamamoto, David Ambrozak, Joseph P. Casazza, Richard Haubrich, Mark Connors, Julie Ake, Jerome H. Kim, Richard A. Koup

published 17 Dec 2015

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Virulence-Dependent Alterations in the Kinetics of Immune Cells during Pulmonary Infection by Mycobacterium tuberculosis

Woo Sik Kim, Jong-Seok Kim, Seung Bin Cha, Seung Jung Han, HongMin Kim, Kee Woong Kwon, So Jeong Kim, Seok-Yong Eum, Sang-Nae Cho, Sung Jae Shin

published 16 Dec 2015

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Role of Nucleotide-Binding Oligomerization Domain-Containing (NOD) 2 in Host Defense during Pneumococcal Pneumonia

Tijmen J. Hommes, Miriam H. van Lieshout, Cornelis van ‘t Veer, Sandrine Florquin, Hester J. Bootsma, Peter W. Hermans, Alex F. de Vos, Tom van der Poll

published 16 Dec 2015

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Cytokine and Antibody Based Diagnostic Algorithms for Sputum Culture-Positive Pulmonary Tuberculosis

Tao Chen, Jinfei Lin, Wei Wang, Joy Fleming, Liang Chen, Yunxia Wang, Haicheng Li, Huixin Guo, Jie Zhou, Xunxun Chen, Yuhui Chen, Qinghua Liao, Yang Shu, Yaoju Tan, Meiling Yu, Guozhou Li, Lin Zhou, Qiu Zhong, Lijun Bi, Lina Guo, Meigui Zhao

published 16 Dec 2015

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Effect of Tumor Necrosis Factor Inhibitor Therapy on Osteoclasts Precursors in Ankylosing Spondylitis

Inês P. Perpétuo, Rita Raposeiro, Joana Caetano-Lopes, Elsa Vieira-Sousa, Raquel Campanilho-Marques, Cristina Ponte, Helena Canhão, Mari Ainola, João E. Fonseca

published 16 Dec 2015

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Long-Lived αMUPA Mice Show Attenuation of Cardiac Aging and Leptin-Dependent Cardioprotection

Esther Levy, Ran Kornowski, Reut Gavrieli, Ilana Fratty, Gabriel Greenberg, Maayan Waldman, Einat Birk, Asher Shainberg, Amit Akirov, Ruth Miskin, Edith Hochhauser

published 16 Dec 2015

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Serum Vaspin Levels Are Associated with the Development of Clinically Manifest Arthritis in Autoantibody-Positive Individuals

Karen I. Maijer, Elena Neumann, Ulf Müller-Ladner, Daniël A. C. A. D. Drop, Tamara H. Ramwadhdoebe, Ivy Y. K. Choi, Daniëlle M. Gerlag, Maria J. H. de Hair, Paul P. Tak

published 15 Dec 2015

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Bacterial Ghosts of Escherichia coli Drive Efficient Maturation of Bovine Monocyte-Derived Dendritic Cells

Irshad Ahmed Hajam, Pervaiz Ahmad Dar, Elamurugan Appavoo, Subodh Kishore, Veerakyathappa Bhanuprakash, Kondabattula Ganesh

published 15 Dec 2015

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Brazilian Red Propolis Attenuates Inflammatory Signaling Cascade in LPS-Activated Macrophages

Bruno Bueno-Silva, Dione Kawamoto, Ellen S. Ando-Suguimoto, Severino M. Alencar, Pedro L. Rosalen, Marcia P. A. Mayer

published 14 Dec 2015

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Single-Cell Cytokine Gene Expression in Peripheral Blood Cells Correlates with Latent Tuberculosis Status

Pooja Vir, Riccardo Arrigucci, Karim Lakehal, Amy L. Davidow, Richard Pine, Sanjay Tyagi, Yuri Bushkin, Alfred Lardizabal, Maria Laura Gennaro

published 14 Dec 2015

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