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Molecular development

Metformin Changes the Relationship between Blood Monocyte Toll-Like Receptor 4 Levels and Nonalcoholic Fatty Liver Disease—Ex Vivo Studies

Agnieszka Zwolak, Olga Słabczyńska, Justyna Semeniuk, Jadwiga Daniluk, Agnieszka Szuster-Ciesielska

published 01 Mar 2016

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A Study to Investigate the Efficacy and Safety of an Anti-Interleukin-18 Monoclonal Antibody in the Treatment of Type 2 Diabetes Mellitus

Elizabeth A. McKie, Juliet L. Reid, Prafull C. Mistry, Stephen L. DeWall, Lee Abberley, Philip D. Ambery, Blas Gil-Extremera

published 01 Mar 2016

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TLR4 Activation Promotes Bone Marrow MSC Proliferation and Osteogenic Differentiation via Wnt3a and Wnt5a Signaling

Xiaoqing He, Hai Wang, Tao Jin, Yongqing Xu, Liangbin Mei, Jun Yang

published 01 Mar 2016

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Triglyceride Glucose-Body Mass Index Is a Simple and Clinically Useful Surrogate Marker for Insulin Resistance in Nondiabetic Individuals

Leay-Kiaw Er, Semon Wu, Hsin-Hua Chou, Lung-An Hsu, Ming-Sheng Teng, Yu-Chen Sun, Yu-Lin Ko

published 01 Mar 2016

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Effect of Serum Leptin on Weight Gain Induced by Olanzapine in Female Patients with Schizophrenia

Nobuto Tsuneyama, Yutaro Suzuki, Kazushi Sawamura, Takuro Sugai, Naoki Fukui, Junzo Watanabe, Shin Ono, Mami Saito, Toshiyuki Someya

published 01 Mar 2016

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Characterization and Vaccine Potential of Outer Membrane Vesicles Produced by Haemophilus parasuis

William D. McCaig, Crystal L. Loving, Holly R. Hughes, Susan L. Brockmeier

published 01 Mar 2016

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Nicotinic Acetylcholine Receptors Modulate Bone Marrow-Derived Pro-Inflammatory Monocyte Production and Survival

Stéphanie St-Pierre, Wei Jiang, Patrick Roy, Camille Champigny, Éric LeBlanc, Barbara J. Morley, Junwei Hao, Alain R. Simard

published 29 Feb 2016

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Deciphering Mode of Action of Functionally Important Regions in the Intrinsically Disordered Paxillin (Residues 1-313) Using Its Interaction with FAT (Focal Adhesion Targeting Domain of Focal Adhesion Kinase)

Muniasamy Neerathilingam, Sneha G. Bairy, Sumukh Mysore

published 29 Feb 2016

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Coordinated Activation of Toll-Like Receptor8 (TLR8) and NLRP3 by the TLR8 Agonist, VTX-2337, Ignites Tumoricidal Natural Killer Cell Activity

Gregory N. Dietsch, Hailing Lu, Yi Yang, Chihiro Morishima, Laura Q. Chow, Mary L. Disis, Robert M. Hershberg

published 29 Feb 2016

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CD73 Expressed on γδ T Cells Shapes Their Regulatory Effect in Experimental Autoimmune Uveitis

Dongchun Liang, Aijun Zuo, Ronglan Zhao, Hui Shao, Willi K. Born, Rebecca L. O'Brien, Henry J. Kaplan, Deming Sun

published 26 Feb 2016

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Identification of Adjuvantic Activity of Amphotericin B in a Novel, Multiplexed, Poly-TLR/NLR High-Throughput Screen

Alex C. D. Salyer, Giuseppe Caruso, Karishma K. Khetani, Lauren M. Fox, Subbalakshmi S. Malladi, Sunil A. David

published 26 Feb 2016

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Soluble Vascular Cell Adhesion Molecule-1 (sVCAM-1) Is Elevated in Bronchoalveolar Lavage Fluid of Patients with Acute Respiratory Distress Syndrome

Engi F. Attia, Sarah E. Jolley, Kristina Crothers, Lynn M. Schnapp, W. Conrad Liles

published 26 Feb 2016

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CDDO-Me Redirects Activation of Breast Tumor Associated Macrophages

Michael S. Ball, Emilie P. Shipman, Hyunjung Kim, Karen T. Liby, Patricia A. Pioli

published 26 Feb 2016

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