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Model organisms

Adeno-Associated virus 8 delivers an immunomodulatory peptide to mouse liver more efficiently than to rat liver

Yuqing Wang, Ayrea Hurley, Marco De Giorgi, Mark R. Tanner, Rong-Chi Hu, Michael W. Pennington, William R. Lagor, Christine Beeton

published 11 Apr 2023

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Enabling low-cost and robust essentiality studies with high-throughput transposon mutagenesis (HTTM)

Antoine Champie, Amélie De Grandmaison, Simon Jeanneau, Frédéric Grenier, Pierre-Étienne Jacques, Sébastien Rodrigue

published 11 Apr 2023

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Preclinical trials in Alzheimer’s disease: Sample size and effect size for behavioural and neuropathological outcomes in 5xFAD mice

Mahvish Faisal, Jana Aid, Bekzod Nodirov, Benjamin Lee, Miriam A. Hickey

published 10 Apr 2023

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Effects of Mexican Ganoderma lucidum extracts on liver, kidney, and the gut microbiota of Wistar rats: A repeated dose oral toxicity study

María E. Meneses, Daniel Martínez-Carrera, Laura González-Ibáñez, Nimbe Torres, Mónica Sánchez-Tapia, Claudia C. Márquez-Mota, Gilmar Rendón, Vladimir Mitzi, Alfredo Morales, Isaac Tello-Salgado, Armando R. Tovar

published 06 Apr 2023

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Natural β-carotene prevents acute lung injury induced by cyclophosphamide in mice

Farouk K. El-Baz, Sami I. Ali, Rania Elgohary, Abeer Salama

published 05 Apr 2023

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Bacterial profile, their antibiotic susceptibility pattern, and associated factors of urinary tract infections in children at Hiwot Fana Specialized University Hospital, Eastern Ethiopia

Shambel Mekonnen, Tewodros Tesfa, Tadesse Shume, Fikru Tebeje, Kedir Urgesa, Fitsum Weldegebreal

published 05 Apr 2023

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A seeding-based neuronal model of tau aggregation for use in drug discovery

Ines S. Amorim, Sylvie Challal, Laetitia Cistarelli, Thierry Dorval, Laurene Abjean, Manuelle Touzard, Nicolas Arbez, Arnaud François, Fany Panayi, Ross Jeggo, Erika Cecon, Atsuro Oishi, Julie Dam, Ralf Jockers, Patricia Machado

published 04 Apr 2023

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Multiomic characterization of disease progression in mice lacking dystrophin

Mirko Signorelli, Roula Tsonaka, Annemieke Aartsma-Rus, Pietro Spitali

published 31 Mar 2023

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High signal-to-noise imaging of spontaneous and 5 ns electric pulse-evoked Ca²⁺ signals in GCaMP6f-expressing adrenal chromaffin cells isolated from transgenic mice

Ciara Viola, Thomas W. Gould, Nicole Procacci, Normand Leblanc, Josette Zaklit, Gale L. Craviso

published 31 Mar 2023

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Enhanced therapeutic window for antimicrobial Pept-ins by investigating their structure-activity relationship

Guiqin Wu, Laleh Khodaparast, Ladan Khodaparast, Matthias De Vleeschouwer, Nikolaos Louros, Rodrigo Gallardo, Pengpeng Yi, Frederic Rousseau, Joost Schymkowitz

published 31 Mar 2023

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Protease inhibition, in vitro antibacterial and IFD/MM-GBSA studies of ciprofloxacin-based acetanilides

Rabia Akhtar, Ameer Fawad Zahoor, Asim Mansha, Shagufta Kamal, Samreen Gul Khan, Zohaib Raza, Kulsoom Ghulam Ali

published 31 Mar 2023

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Impact of the yeast S0/uS2-cluster ribosomal protein rpS21/eS21 on rRNA folding and the architecture of small ribosomal subunit precursors

Gisela Pöll, Joachim Griesenbeck, Herbert Tschochner, Philipp Milkereit

published 30 Mar 2023

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Another advantage of multi-locus variable-number tandem repeat analysis that can putatively subdivide enterohemorrhagic Escherichia coli O157 strains into clades by maximum a posteriori estimation

Shinichiro Hirai, Eiji Yokoyama, Naoshi Ando, Junji Seto, Kyoko Hazama, Keigo Enomoto, Hidemasa Izumiya, Yukihiro Akeda, Makoto Ohnishi

published 30 Mar 2023

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