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Microglial cells

TRIM37-mediated stabilization of PEX5 via monoubiquitination attenuates oxidative stress and demyelination in multiple sclerosis insights from EAE and LPC-induced experimental models

Lai Jiang, Yue Jin, Yujia Han, Jin Fu

Caveolin-1 knockout improves CFA-induced inflammatory pain in adult mice through modulating the cGAS STING pathway and autophagy

Huan Chang, Cancan Cheng, [ ... ], Fan Zhang

Role of mTORC1 signaling in postnatal microglia activation preceding neurodegeneration in a mouse model for Niemann-Pick disease Type C

Caroline E. Murray, David S. Betancourt-Trompa, [ ... ], Ileana Soto

Phosphatidylcholine suppresses inflammatory responses in LPS-stimulated MG6 microglial cells by inhibiting NF-κB/JNK/p38 MAPK signaling

Sachiko Mizuno, Yuki Kurobe-Takashima, [ ... ], Shoko Kobayashi

Peripheral administration of blood from tau transgenic animals exacerbates brain tau-associated pathology

Laura Vegas-Gomez, Matias Pizarro, [ ... ], Ines Moreno-Gonzalez

IFN-γ signaling is required for the efficient replication of murine hepatitis virus (MHV) strain JHM in the brains of infected mice

Catherine M. Kerr, Macie A. Proctor-Roser, [ ... ], Anthony R. Fehr

A graded neonatal mouse model of necrotizing enterocolitis demonstrates that mild enterocolitis is sufficient to activate microglia and increase cerebral cytokine expression

Cuilee Sha, Trevor Van Brunt, [ ... ], Helen Hsieh

3-Deoxysappanchalcone attenuates LPS-induced neuroinflammation in microglia cell culture and ameliorates cognitive impairment in traumatic brain injury

Zemeng Li, Dangli Ren, [ ... ], Hongtao Sun

Findings from transcriptomics and immunohistochemistry indicate an autoimmune disease targeting brainstem inhibitory interneurons in bovine spastic paresis

Frederik Krull, Shahrbanou Hosseini, Martina Bleyer, Bertram Brenig

Hancinone possesses potentials on increasing the ability of HMC3 cells to phagocytosis of Aβ_1-42 via TREM2/Syk/PI3K/AKT/mTOR signaling pathway

Yushun Zhou, Guran Yu, Hao Li

Klotho null mutation leads to retinal degeneration characterized by functional impairment, gliosis, and deposition of amyloid-beta and hyperphosphorylated tau proteins

Zhi-Jia Chen, Chun-Yen Wu, [ ... ], David Pei-Cheng Lin

Microglia remodeling in the visual thalamus of the DBA/2J mouse model of glaucoma

Jennifer L. Thompson, Shaylah McCool, [ ... ], Matthew J. Van Hook

MiR-129-5p alleviates depression and anxiety by increasing astrocyte ATP production partly through targeting deubiquitinase Mysm1

Qiaozhen Qin, Heyang Zhang, [ ... ], Xiaoxia Jiang

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