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Microbicides

“One Teabag Is Better than Four”: Participants Response to the Discontinuation of 2% PRO2000/5 Microbicide Gel in KwaZulu-Natal, South Africa

Mitzy Gafos, Misiwe Mzimela, Hlengiwe Ndlovu, Nkosinathi Mhlongo, Yael Hoogland, Richard Mutemwa

published 21 Jan 2011

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A Phase I Randomized Placebo Controlled Trial of the Safety of 3% SPL7013 Gel (VivaGel®) in Healthy Young Women Administered Twice Daily for 14 Days

Craig R. Cohen, Joelle Brown, Anna-Barbara Moscicki, Elizabeth A. Bukusi, Jeremy R. A. Paull, Clare F. Price, Stephen Shiboski

published 20 Jan 2011

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An Antiretroviral/Zinc Combination Gel Provides 24 Hours of Complete Protection against Vaginal SHIV Infection in Macaques

Jessica Kenney, Meropi Aravantinou, Rachel Singer, Mayla Hsu, Aixa Rodriguez, Larisa Kizima, Ciby J. Abraham, Radhika Menon, Samantha Seidor, Anne Chudolij, Agegnehu Gettie, James Blanchard, Jeffrey D. Lifson, Michael Piatak Jr., Jose A. Fernández-Romero, Thomas M. Zydowsky, Melissa Robbiani

published 05 Jan 2011

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The Formulated Microbicide RC-101 Was Safe and Antivirally Active Following Intravaginal Application in Pigtailed Macaques

Alexander M. Cole, Dorothy L. Patton, Lisa C. Rohan, Amy L. Cole, Yvonne Cosgrove-Sweeney, Nicole A. Rogers, Deena Ratner, Alexandra B. Sassi, Carol Lackman-Smith, Patrick Tarwater, Bharat Ramratnam, Piotr Ruchala, Robert I. Lehrer, Alan J. Waring, Phalguni Gupta

published 29 Nov 2010

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Increasing the Effectiveness of Vaginal Microbicides: A Biophysical Framework to Rethink Behavioral Acceptability

Stéphane Verguet, Bethany Young Holt, Andrew J. Szeri

published 22 Nov 2010

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Structure Activity Relationship of Dendrimer Microbicides with Dual Action Antiviral Activity

David Tyssen, Scott A. Henderson, Adam Johnson, Jasminka Sterjovski, Katie Moore, Jennifer La, Mark Zanin, Secondo Sonza, Peter Karellas, Michael P. Giannis, Guy Krippner, Steve Wesselingh, Tom McCarthy, Paul R. Gorry, Paul A. Ramsland, Richard Cone, Jeremy R. A. Paull, Gareth R. Lewis, Gilda Tachedjian

published 23 Aug 2010

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Assessing the Accuracy of Adherence and Sexual Behaviour Data in the MDP301 Vaginal Microbicides Trial Using a Mixed Methods and Triangulation Model

Robert Pool, Catherine M. Montgomery, Neetha S. Morar, Oliver Mweemba, Agnes Ssali, Mitzy Gafos, Shelley Lees, Jonathan Stadler, Andrew Nunn, Angela Crook, Richard Hayes, Sheena McCormack

published 21 Jul 2010

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A Mixed Methods and Triangulation Model for Increasing the Accuracy of Adherence and Sexual Behaviour Data: The Microbicides Development Programme

Robert Pool, Catherine M. Montgomery, Neetha S. Morar, Oliver Mweemba, Agnes Ssali, Mitzy Gafos, Shelley Lees, Jonathan Stadler, Angela Crook, Andrew Nunn, Richard Hayes, Sheena McCormack

published 21 Jul 2010

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Anti-HIV Activity in Cervical-Vaginal Secretions from HIV-Positive and -Negative Women Correlate with Innate Antimicrobial Levels and IgG Antibodies

Mimi Ghosh, John V. Fahey, Zheng Shen, Timothy Lahey, Susan Cu-Uvin, Zhijin Wu, Kenneth Mayer, Peter F. Wright, John C. Kappes, Christina Ochsenbauer, Charles R. Wira

published 29 Jun 2010

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HIV-1 Neutralization Profile and Plant-Based Recombinant Expression of Actinohivin, an Env Glycan-Specific Lectin Devoid of T-Cell Mitogenic Activity

Nobuyuki Matoba, Adam S. Husk, Brian W. Barnett, Michelle M. Pickel, Charles J. Arntzen, David C. Montefiori, Atsushi Takahashi, Kazunobu Tanno, Satoshi Omura, Huyen Cao, Jason P. Mooney, Carl V. Hanson, Haruo Tanaka

published 15 Jun 2010

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Are Women Who Work in Bars, Guesthouses and Similar Facilities a Suitable Study Population for Vaginal Microbicide Trials in Africa?

Andrew Vallely, Ian R. Hambleton, Stella Kasindi, Louise Knight, Suzanna C. Francis, Tobias Chirwa, Dean Everett, Charles Shagi, Claire Cook, Celia Barberousse, Deborah Watson-Jones, John Changalucha, David Ross, Richard J. Hayes, for the Microbicides Development Programme

published 14 May 2010

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Development of and Access to Products for Neglected Diseases

Joshua Cohen, Maria Staroselsky Dibner, Andrew Wilson

published 12 May 2010

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Development of an HIV-1 Specific Microbicide Using Caulobacter crescentus S-Layer Mediated Display of CD4 and MIP1α

John F. Nomellini, Carmen Li, Danielle Lavallee, Iryna Shanina, Lisa A. Cavacini, Marc S. Horwitz, John Smit

published 28 Apr 2010

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