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Microbicides

Selective Impact of HIV Disease Progression on the Innate Immune System in the Human Female Reproductive Tract

Timothy Lahey, Mimi Ghosh, John V. Fahey, Zheng Shen, Lucy R. Mukura, Yan Song, Susan Cu-Uvin, Kenneth H. Mayer, Peter F. Wright, John C. Kappes, Christina Ochsenbauer, Charles R. Wira

published 04 Jun 2012

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Efficacy, Stability, and Biosafety of Sifuvirtide Gel as a Microbicide Candidate against HIV-1

Liangzhu Li, Yinyin Ben, Songhua Yuan, Shibo Jiang, Jianqing Xu, Xiaoyan Zhang

published 16 May 2012

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Anti-HIV-1 Activity of a New Scorpion Venom Peptide Derivative Kn2-7

Yaoqing Chen, Luyang Cao, Maohua Zhong, Yan Zhang, Chen Han, Qiaoli Li, Jingyi Yang, Dihan Zhou, Wei Shi, Benxia He, Fang Liu, Jie Yu, Ying Sun, Yuan Cao, Yaoming Li, Wenxin Li, Deying Guo, Zhijian Cao, Huimin Yan

published 19 Apr 2012

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Quality Control and Performance of HIV Rapid Tests in a Microbicide Clinical Trial in Rural KwaZulu-Natal

Nina von Knorring, Mitzy Gafos, Motsei Ramokonupi, Ute Jentsch, the MDP Team

published 30 Jan 2012

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SHIV-162P3 Infection of Rhesus Macaques Given Maraviroc Gel Vaginally Does Not Involve Resistant Viruses

Athe M. N. Tsibris, Urboshi Pal, Allison L. Schure, Ronald S. Veazey, Kevin J. Kunstman, Timothy J. Henrich, P. J. Klasse, Steven M. Wolinsky, Daniel R. Kuritzkes, John P. Moore

published 02 Dec 2011

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A Multi-Compartment, Single and Multiple Dose Pharmacokinetic Study of the Vaginal Candidate Microbicide 1% Tenofovir Gel

Jill L. Schwartz, Wes Rountree, Angela D. M. Kashuba, Vivian Brache, Mitchell D. Creinin, Alfred Poindexter, Brian P. Kearney

published 19 Oct 2011

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First Phase 1 Double-Blind, Placebo-Controlled, Randomized Rectal Microbicide Trial Using UC781 Gel with a Novel Index of Ex Vivo Efficacy

Peter A. Anton, Terry Saunders, Julie Elliott, Elena Khanukhova, Robert Dennis, Amy Adler, Galen Cortina, Karen Tanner, John Boscardin, William G. Cumberland, Ying Zhou, Ana Ventuneac, Alex Carballo-Diéguez, Lorna Rabe, Timothy McCormick, Henry Gabelnick, Christine Mauck, Ian McGowan

published 28 Sep 2011

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Inhibition of HIV-1 Infection in Ex Vivo Cervical Tissue Model of Human Vagina by Palmitic Acid; Implications for a Microbicide Development

Xudong Lin, Elena E. Paskaleva, William Chang, Alexander Shekhtman, Mario Canki

published 19 Sep 2011

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SPL7013 Gel (VivaGel®) Retains Potent HIV-1 and HSV-2 Inhibitory Activity following Vaginal Administration in Humans

Clare F. Price, David Tyssen, Secondo Sonza, Ashley Davie, Sonya Evans, Gareth R. Lewis, Shirley Xia, Tim Spelman, Peter Hodsman, Thomas R. Moench, Andrew Humberstone, Jeremy R.A. Paull, Gilda Tachedjian

published 15 Sep 2011

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Acceptability of Carraguard Vaginal Microbicide Gel among HIV-Infected Women in Chiang Rai, Thailand

Sara J. Whitehead, Catherine McLean, Supaporn Chaikummao, Sarah Braunstein, Wat Utaivoravit, Janneke H. van de Wijgert, Philip A. Mock, Taweesap Siraprapasiri, Barbara A. Friedland, Peter H. Kilmarx, Lauri E. Markowitz

published 07 Sep 2011

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HIV Prevalence and Incidence among Sexually Active Females in Two Districts of South Africa to Determine Microbicide Trial Feasibility

Annaléne Nel, Cheryl Louw, Elizabeth Hellstrom, Sarah L. Braunstein, Ina Treadwell, Melanie Marais, Martie de Villiers, Jannie Hugo, Inge Paschke, Chrisna Andersen, Janneke van de Wijgert

published 10 Aug 2011

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A Topical Microbicide Gel Formulation of CCR5 Antagonist Maraviroc Prevents HIV-1 Vaginal Transmission in Humanized RAG-hu Mice

C. Preston Neff, Theresa Kurisu, Thomas Ndolo, Kami Fox, Ramesh Akkina

published 01 Jun 2011

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A Randomized Trial to Assess Anti-HIV Activity in Female Genital Tract Secretions and Soluble Mucosal Immunity Following Application of 1% Tenofovir Gel

Marla J. Keller, Rebecca P. Madan, N. Merna Torres, Melissa J. Fazzari, Sylvia Cho, Sabah Kalyoussef, Gail Shust, Pedro M. M. Mesquita, Nicolette Louissaint, Jianmeng Chen, Hillel W. Cohen, Erin C. Diament, Anna C. Lee, Lydia Soto-Torres, Craig W. Hendrix, Betsy C. Herold

published 25 Jan 2011

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