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Microbicides

High levels of adherence to a rectal microbicide gel and to oral Pre-Exposure Prophylaxis (PrEP) achieved in MTN-017 among men who have sex with men (MSM) and transgender women

Alex Carballo-Diéguez, Ivan C. Balán, William Brown III, Rebecca Giguere, Curtis Dolezal, Cheng-Shiun Leu, Mark A. Marzinke, Craig W. Hendrix, Jeanna M. Piper, Barbra A. Richardson, Cynthia Grossman, Sherri Johnson, Kailazarid Gomez, Stephanie Horn, Ratiya Pamela Kunjara Na Ayudhya, Karen Patterson, Cindy Jacobson, Linda-Gail Bekker, Suwat Chariyalertsak, Anupong Chitwarakorn, Pedro Gonzales, Timothy H. Holtz, Albert Liu, Kenneth H. Mayer, Carmen Zorrilla, Javier Lama, Ian McGowan, Ross D. Cranston

published 27 Jul 2017

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Attitudes and perceptions towards novel objective measures of ARV-based vaginal ring use: Results from a global stakeholder survey

Randy M. Stalter, Jenae Tharaldson, Derek H. Owen, Eunice Okumu, Thomas Moench, Natasha Mack, Elizabeth E. Tolley, Kathleen M. MacQueen

published 14 Jul 2017

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Multicompartmental Pharmacokinetic Model of Tenofovir Delivery to the Rectal Mucosa by an Enema

Yajing Gao, David F. Katz

published 23 Jan 2017

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Project Gel a Randomized Rectal Microbicide Safety and Acceptability Study in Young Men and Transgender Women

Ian McGowan, Ross D. Cranston, Kenneth H. Mayer, Irma Febo, Kathryn Duffill, Aaron Siegel, Jarret C. Engstrom, Alexyi Nikiforov, Seo-Young Park, Rhonda M. Brand, Cindy Jacobson, Rebecca Giguere, Curtis Dolezal, Timothy Frasca, Cheng-Shiun Leu, Jill L. Schwartz, Alex Carballo-Diéguez

published 30 Jun 2016

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Hypothetical Rectal Microbicide Acceptability and Factors Influencing It among Men Who Have Sex with Men in Tianjin, China

Guohong Zhang, Huifang Zhang, Hongxuyang Yu, Zheng Zhao, Jie Yang, Mianzhi Zhang, Minying Zhang

published 31 May 2016

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Drivers of Vaginal Drug Delivery System Acceptability from Internet-Based Conjoint Analysis

Rachel J. Primrose, Toral Zaveri, Alyssa J. Bakke, Gregory R. Ziegler, Howard R. Moskowitz, John E. Hayes

published 21 Mar 2016

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Safety, Acceptability and Adherence of Dapivirine Vaginal Ring in a Microbicide Clinical Trial Conducted in Multiple Countries in Sub-Saharan Africa

Annalene Nel, Linda-Gail Bekker, Elizabeth Bukusi, Elizabeth Hellstrӧm, Philip Kotze, Cheryl Louw, Francis Martinson, Gileard Masenga, Elizabeth Montgomery, Nelisiwe Ndaba, Ariane van der Straten, Neliëtte van Niekerk, Cynthia Woodsong

published 10 Mar 2016

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The Promise of Intravaginal Rings for Prevention: User Perceptions of Biomechanical Properties and Implications for Prevention Product Development

Kate Morrow Guthrie, Sara Vargas, Julia G. Shaw, Rochelle K. Rosen, Jacob J. van den Berg, Patrick F. Kiser, Karen Buckheit, Dana Bregman, Lara Thompson, Kathleen Jensen, Todd Johnson, Robert W. Buckheit

published 22 Dec 2015

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A Multiple siRNA-Based Anti-HIV/SHIV Microbicide Shows Protection in Both In Vitro and In Vivo Models

Sandhya Boyapalle, Weidong Xu, Payal Raulji, Subhra Mohapatra, Shyam S Mohapatra

published 25 Sep 2015

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Unexpected Inflammatory Effects of Intravaginal Gels (Universal Placebo Gel and Nonoxynol-9) on the Upper Female Reproductive Tract: A Randomized Crossover Study

Karen Smith-McCune, Joseph C. Chen, Ruth M. Greenblatt, Uma Shanmugasundaram, Barbara L. Shacklett, Joan F. Hilton, Brittni Johnson, Juan C. Irwin, Linda C Giudice

published 15 Jul 2015

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Enhancing Interferon Regulatory Factor 7 Mediated Antiviral Responses and Decreasing Nuclear Factor Kappa B Expression Limit HIV-1 Replication in Cervical Tissues

Christiane Rollenhage, Sherrill L. Macura, Melissa J. Lathrop, Todd A. Mackenzie, Gustavo F. Doncel, Susana N. Asin

published 29 Jun 2015

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Expression of Genes for Drug Transporters in the Human Female Genital Tract and Modulatory Effect of Antiretroviral Drugs

Karolin Hijazi, Anna M. Cuppone, Kieron Smith, Maria A. Stincarelli, Julia Ekeruche-Makinde, Giulia De Falco, Georgina L. Hold, Robin Shattock, Charles G. Kelly, Gianni Pozzi, Francesco Iannelli

published 23 Jun 2015

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Characteristics of Women Enrolled into a Randomized Clinical Trial of Dapivirine Vaginal Ring for HIV-1 Prevention

Thesla Palanee-Phillips, Katie Schwartz, Elizabeth R. Brown, Vaneshree Govender, Nyaradzo Mgodi, Flavia Matovu Kiweewa, Gonasagrie Nair, Felix Mhlanga, Samantha Siva, Linda-Gail Bekker, Nitesha Jeenarain, Zakir Gaffoor, Francis Martinson, Bonus Makanani, Sarita Naidoo, Arendevi Pather, Jessica Phillip, Marla J. Husnik, Ariane van der Straten, Lydia Soto-Torres, Jared Baeten

published 10 Jun 2015

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