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Microbial mutation

Single HA2 Mutation Increases the Infectivity and Immunogenicity of a Live Attenuated H5N1 Intranasal Influenza Vaccine Candidate Lacking NS1

Brigitte M. Krenn, Andrej Egorov, Ekaterina Romanovskaya-Romanko, Markus Wolschek, Sabine Nakowitsch, Tanja Ruthsatz, Bettina Kiefmann, Alexander Morokutti, Johannes Humer, Janina Geiler, Jindrich Cinatl, Martin Michaelis, Nina Wressnigg, Sanda Sturlan, Boris Ferko, Oleg V. Batishchev, Andrey V. Indenbom, Rong Zhu, Markus Kastner, Peter Hinterdorfer, Oleg Kiselev, Thomas Muster, Julia Romanova

published 07 Apr 2011

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Fitness Ranking of Individual Mutants Drives Patterns of Epistatic Interactions in HIV-1

Javier P. Martínez, Gennady Bocharov, Anna Ignatovich, Jochen Reiter, Matthias T. Dittmar, Simon Wain-Hobson, Andreas Meyerhans

published 31 Mar 2011

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Reassortment and Mutations Associated with Emergence and Spread of Oseltamivir-Resistant Seasonal Influenza A/H1N1 Viruses in 2005–2009

Ji-Rong Yang, Yu-Cheng Lin, Yuan-Pin Huang, Chun-Hui Su, Je Lo, Yu-Lin Ho, Ching-Yuan Yao, Li-Ching Hsu, Ho-Sheng Wu, Ming-Tsan Liu

published 31 Mar 2011

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Spontaneous Emergence of Multiple Drug Resistance in Tuberculosis before and during Therapy

Caroline Colijn, Ted Cohen, Ayalvadi Ganesh, Megan Murray

published 30 Mar 2011

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A Single Base-Pair Change in 2009 H1N1 Hemagglutinin Increases Human Receptor Affinity and Leads to Efficient Airborne Viral Transmission in Ferrets

Akila Jayaraman, Claudia Pappas, Rahul Raman, Jessica A. Belser, Karthik Viswanathan, Zachary Shriver, Terrence M. Tumpey, Ram Sasisekharan

published 02 Mar 2011

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Wider Access to Genotypic Space Facilitates Loss of Cooperation in a Bacterial Mutator

Freya Harrison, Angus Buckling

published 25 Feb 2011

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Influenza A Virus Hemagglutinin Antibody Escape Promotes Neuraminidase Antigenic Variation and Drug Resistance

Scott E. Hensley, Suman R. Das, James S. Gibbs, Adam L. Bailey, Loren M. Schmidt, Jack R. Bennink, Jonathan W. Yewdell

published 22 Feb 2011

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The Role of Recombination for the Coevolutionary Dynamics of HIV and the Immune Response

Rafal Mostowy, Roger D. Kouyos, David Fouchet, Sebastian Bonhoeffer

published 18 Feb 2011

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Constrained Pattern of Viral Evolution in Acute and Early HCV Infection Limits Viral Plasticity

Katja Pfafferott, Silvana Gaudieri, Axel Ulsenheimer, Ian James, Malte Heeg, David Nolan, Mina John, Andri Rauch, Simon Mallal, Andrew Lucas, Paul Klenerman, Helmut M. Diepolder, Michaela Lucas

published 08 Feb 2011

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Differences in Reversion of Resistance Mutations to Wild-Type under Structured Treatment Interruption and Related Increase in Replication Capacity

Agnes C. Paquet, John Baxter, Jodi Weidler, Yolanda Lie, Jody Lawrence, Rose Kim, Michael Bates, Eoin Coakley, Colombe Chappey

published 31 Jan 2011

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Dynamics of Viral Evolution and CTL Responses in HIV-1 Infection

Yi Liu, John P. McNevin, Sarah Holte, M. Juliana McElrath, James I. Mullins

published 20 Jan 2011

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Mutation of HIV-1 Genomes in a Clinical Population Treated with the Mutagenic Nucleoside KP1461

James I. Mullins, Laura Heath, James P. Hughes, Jessica Kicha, Sheila Styrchak, Kim G. Wong, Ushnal Rao, Alexis Hansen, Kevin S. Harris, Jean-Pierre Laurent, Deyu Li, Jeffrey H. Simpson, John M. Essigmann, Lawrence A. Loeb, Jeffrey Parkins

published 14 Jan 2011

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Nationwide Molecular Surveillance of Pandemic H1N1 Influenza A Virus Genomes: Canada, 2009

Morag Graham, Binhua Liang, Gary Van Domselaar, Nathalie Bastien, Carole Beaudoin, Shaun Tyler, Brynn Kaplen, Erika Landry, the National Influenza A/H1N1pdm Genomics Study Team (NIGST) , Yan Li

published 07 Jan 2011

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