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Microbial mutation

Amino acid T25 in the substrate-binding domain of SARS-CoV-2 nsp5 is involved in viral replication in the mouse lung

Yoshiro Sugiura, Kenta Shimizu, Tatsuki Takahashi, Shiori Ueno, Haruka Tanigou, Sodbayasgalan Amarbayasgalan, Wataru Kamitani

published 06 Dec 2024

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Systematic analysis of SARS-CoV-2 Omicron subvariants’ impact on B and T cell epitopes

Ruba Al Khalaf, Anna Bernasconi, Pietro Pinoli

published 19 Sep 2024

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Viral load suppression and HIV-1 drug resistance mutations in persons with HIV on TLD/TAFED in Zambia

Emmanuel L. Luwaya, Lackson Mwape, Kaole Bwalya, Chileleko Siakabanze, Benson M. Hamooya, Sepiso K. Masenga

published 06 Sep 2024

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Mutations in the F protein of the live-attenuated respiratory syncytial virus vaccine candidate ΔNS2/Δ1313/I1314L increase the stability of infectivity and content of prefusion F protein

Judith Alamares-Sapuay, Michael Kishko, Charles Lai, Mark Parrington, Simon Delagrave, Richard Herbert, Ashley Castens, Joanna Swerczek, Cindy Luongo, Lijuan Yang, Peter L. Collins, Ursula J. Buchholz, Linong Zhang

published 09 Apr 2024

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Unravelling the link between SARS-CoV-2 mutation frequencies, patient comorbidities, and structural dynamics

Amirah Azzeri, Nurul Azmawati Mohamed, Saarah Huurieyah Wan Rosli, Muttaqillah Najihan Abdul Samat, Zetti Zainol Rashid, Muhamad Arif Mohamad Jamali, Muhammad Zarul Hanifah Md Zoqratt, Muhammad Azamuddeen Mohammad Nasir, Harpreet Kaur Ranjit Singh, Liyana Azmi

published 14 Mar 2024

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Genomic characterization of SARS-CoV-2 in Guinea, West Africa

Mamadou Saliou Sow, Josue Togo, Lacy M. Simons, Souleymane Taran Diallo, Mohamed Lamine Magassouba, Mamadou Bhoye Keita, Anou Moise Somboro, Youssouf Coulibaly, Egon A. Ozer, Judd F. Hultquist, Robert Leo Murphy, Almoustapha Issiaka Maiga, Mamoudou Maiga, Ramon Lorenzo-Redondo

published 06 Mar 2024

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Immunocapture of cell surface proteins embedded in HIV envelopes uncovers considerable virion genetic diversity associated with different source cell types

Sarah Sabour, Jin-fen Li, Jonathan T. Lipscomb, Ariana P. Santos Tino, Jeffrey A. Johnson

published 27 Feb 2024

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Differential laboratory passaging of SARS-CoV-2 viral stocks impacts the in vitro assessment of neutralizing antibodies

Aram Avila-Herrera, Jeffrey A. Kimbrel, Jose Manuel Martí, James Thissen, Edwin A. Saada, Tracy Weisenberger, Kathryn T. Arrildt, Brent W. Segelke, Jonathan E. Allen, Adam Zemla, Monica K. Borucki

published 25 Jan 2024

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Machine learning-based approach KEVOLVE efficiently identifies SARS-CoV-2 variant-specific genomic signatures

Dylan Lebatteux, Hugo Soudeyns, Isabelle Boucoiran, Soren Gantt, Abdoulaye Baniré Diallo

published 19 Jan 2024

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Pre-treatment 18F-FDG-PET/CT parameters as biomarkers for progression free survival, best overall response and overall survival in metastatic melanoma patients undergoing first-line immunotherapy

Felix Peisen, Annika Gerken, Isabel Dahm, Konstantin Nikolaou, Thomas Eigentler, Teresa Amaral, Jan H. Moltz, Ahmed E. Othman, Sergios Gatidis

published 05 Jan 2024

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The PitA protein contributes to colistin susceptibility in Pseudomonas aeruginosa

Mareike B. Erdmann, Paul P. Gardner, Iain L. Lamont

published 12 Oct 2023

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Different aspects in explaining how mutations could affect the binding mechanism of receptor binding domain of SARS-CoV-2 spike protein in interaction with ACE2

Farzaneh Jafary, Farzane Abasi Joozdani, Kiana Shahzamani, Sepideh Jafari, Hossein Mirhendi, Mohamad Reza Ganjalikhany

published 08 Sep 2023

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In silico epitope prediction and evolutionary analysis reveals capsid mutation patterns for enterovirus B

Hui Wang, Yulu Fang, Yongtao Jia, Jiajie Tang, Changzheng Dong

published 28 Aug 2023

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