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Microbial genetics

PGAP3 is expressed at increased levels in asthmatic ASM and is associated with increased ASM proliferation, contractility and expression of GATA3 and ALOX5

Eric Leslie, Marina Miller, Allison Lafuze, Sofya Svyatskaya, Gil-Soon Choi, Joshua L. Kennedy, Yung-An Huang, Taylor A. Doherty, David H. Broide

published 25 Mar 2025

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Improving the production of baculovirus expression vector by overexpression of IE0/IE1 through tandem promoter

Sijun He, Weining Li, Ruirui Zhang, Hao Nan, Wangcheng Song, Xiaodong Xu

published 25 Mar 2025

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Detection of hepatitis B virus mRNA from single cell RNA sequencing data without prior knowledge

Nicolaas Van Renne, Thomas Vanwolleghem

published 11 Feb 2025

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Characterizing temporal and global host innate immune responses against SARS-CoV-1 and -2 infection in pathologically relevant human lung epithelial cells

Vivian Y. Tat, Aleksandra K. Drelich, Pinghan Huang, Kamil Khanipov, Jason C. Hsu, Steven G. Widen, Chien-Te Kent Tseng, George Golovko

published 28 Jan 2025

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An insight into the genome-wide analysis of bacterial defense mechanisms in a uropathogenic Morganella morganii isolate from Bangladesh

Syed Muktadir Al Sium, Barna Goswami, Sanjana Fatema Chowdhury, Showti Raheel Naser, Mihir Kanti Sarkar, Md. Jobaid Faruq, Md. Ahashan Habib, Shahina Akter, Tanjina Akhtar Banu, Md. Murshed Hasan Sarkar, Md. Salim Khan

published 23 Jan 2025

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Longitudinal host transcriptional responses to SARS-CoV-2 infection in adults with extremely high viral load

Vasanthi Avadhanula, Chad J. Creighton, Laura Ferlic-Stark, Divya Nagaraj, Yiqun Zhang, Richard Sucgang, Erin G. Nicholson, Anubama Rajan, Vipin Kumar Menon, Harshavardhan Doddapaneni, Donna Marie Muzny, Ginger A. Metcalf, Sara Joan Javornik Cregeen, Kristi Louise Hoffman, Richard A. Gibbs, Joseph F. Petrosino, Pedro A. Piedra

published 16 Jan 2025

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miRNA-328-3p regulates ZO-1 expression and inhibits PEDV proliferation via the PLC-β1-PKC pathway

Han Zhao, Jiayu Zhang, Dengliang Li, Zhanding Cui, Jiuyuan Liu, Di Bao, Yiming Wei, Xinyue Zhang, Zhimin Wu, Tianqi Zhang, Kai Wang, Shushuai Yi, Wei Lian, Guixue Hu

published 03 Jan 2025

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Genomic insights into the probiotic potential and genes linked to gallic acid metabolism in Pediococcus pentosaceus MBBL6 isolated from healthy cow milk

Md. Morshedur Rahman, Naim Siddique, Soharth Hasnat, Md. Tanvir Rahman, Mustafizur Rahman, Munirul Alam, Ziban Chandra Das, Tofazzal Islam, M. Nazmul Hoque

published 26 Dec 2024

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Exploring the host response in infected lung organoids using NanoString technology: A statistical analysis of gene expression data

Mostafa Rezapour, Stephen J. Walker, David A. Ornelles, Muhammad Khalid Khan Niazi, Patrick M. McNutt, Anthony Atala, Metin Nafi Gurcan

published 26 Nov 2024

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Increased QPCT gene expression by the hepatitis B virus promotes HBV replication

Conghui Zhang, Qingfeng Ma, Wei Wang, Hui Song, Xue Wang, Fengxia Xu, Chengliang Zhu, Xinghui Liu

published 12 Nov 2024

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Tracking inflammation resolution signatures in lungs after SARS-CoV-2 omicron BA.1 infection of K18-hACE2 mice

Agnes Carolin, Kexin Yan, Cameron R. Bishop, Bing Tang, Wilson Nguyen, Daniel J. Rawle, Andreas Suhrbier

published 12 Nov 2024

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Transcriptomic analyses of host-virus interactions during in vitro infection with wild-type and glycoprotein g-deficient (ΔgG) strains of ILTV in primary and continuous cell cultures

Gayathri Gopakumar, Andrés Diaz-Méndez, Mauricio J. C. Coppo, Carol A. Hartley, Joanne M. Devlin

published 11 Oct 2024

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Prediction of antimicrobial resistance of Klebsiella pneumoniae from genomic data through machine learning

Chiara Condorelli, Emanuele Nicitra, Nicolò Musso, Dafne Bongiorno, Stefania Stefani, Lucia Valentina Gambuzza, Vincenza Carchiolo, Mattia Frasca

published 18 Sep 2024

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