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Methylation

Whole genome DNA methylation patterns in tissue and cfDNA associated with fibrosis reflect the complex signature of MASLD

Jongseong Ahn, Soyeon Kim, Jae Yoon Jeong, Sunghoon Heo, Kyung-hee Pyo, Eun-Ae Shin, Wonsik Kim, Jae-Ho Lee, Na Ryung Choi, Han Ah Lee, Hwang-Phill Kim, Sang-Hyun Song, Hwi Young Kim, Tae-You Kim, Jung Weon Lee

published 17 Jul 2025

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Measuring technical variability in illumina DNA methylation microarrays

Anderson A. Butler, Jason J. Kras, Karolina P. Chwalek, Enrique I. Ramos, Isaac J. Bishof, David S. Vogel, Daniel L. Vera

published 11 Jul 2025

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Rationale and study protocol of the MAMELI Cohort study (Mapping the Methylation of repetitive elements to track the Exposome effects on health: the city of Legnano as a Living lab)

Valentina Bollati, Federica Rota, Laura Dioni, Chiara Favero, Simona Iodice, Marta Gallazzi, Andrea Spinazzè, Giacomo Fanti, Davide Campagnolo, Tiago Nardi, Davide Biganzoli, Eva Dariol, Rachele Matsagani, Mirjam Hoxha, Paola Monti, Benedetta Albetti, Letizia Tarantini, Davide Barbuto, Ester Luconi, Giuseppe Marano, Giacomo Biganzoli, Roberta Biciuffi, Patrizia Boracchi, Domenico M. Cavallo, Pilar M. Guerrieri, Fabio Mosca, Stefano Gustincich, Giovanni Sanesi, Luca Ferrari, Michele Carugno, Silvia Fustinoni, Angela Cecilia Pesatori, Luca Pandolfini, Michele Miragoli, Andrea Cattaneo, Elia Biganzoli

published 09 Jul 2025

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Leveraging molecular-QTL co-association to predict novel disease-associated genetic loci using a graph convolutional neural network

Julian Ng-Kee-Kwong, Andrew D. Bretherick

published 10 Jun 2025

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Polypyrimidine tract binding proteins PTBP1 and PTBP2 associate with distinct proteins and have distinct post-translational modifications in neuronal nuclear extract

Michael E. Sullivan, Jacob A. Edberg, Christopher I. Nunez, Herbert L. Axelrod, Niroshika M. Keppetipola

published 04 Jun 2025

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Genome-wide DNA methylation analysis of hippocampal tissue in a murine model of attention deficit-hyperactivity disorder

Rodrigo Vidal, Ignacio Lopez, Gonzalo Ugarte, Darwin Contreras, Ricardo Piña, Felipe Godoy, Carlos Rozas, David Rubio, Carola Mantellero, Luis Constandil, Jorge Escobar, Bernardo Morales

published 04 Jun 2025

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AD-GCN: A novel graph convolutional network integrating multi-omics data for enhanced Alzheimer’s disease diagnosis

Zilu Li, Qingyun Li, Xiaoqing Li, Wei Luo, Haiyan Guo, Chunyan Zhao, Canzhen Yang, Anke Xie, Kai Hu, Yangfan Guo

published 02 Jun 2025

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Integration of bioinformatics and identification of the role of m6A genes in NAFLD

Jianguo Ma, Rongyi Xu, Renlin Li, Yangyang Fu, Jing Xu, Lei Zhou, Yan Qi

published 28 May 2025

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Epigenetic regulation of individual components of combined hepatocellular-cholangiocarcinoma

Kyle M. Schachtschneider, Luke N. Redlon, Ryan Peter Lokken, Yu-Hui Huang, Grace Guzman, Lawrence B. Schook, Ron C. Gaba

published 27 May 2025

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Epigenetic assessments of alcohol consumption predict mortality in smokers at risk for lung cancer in the prostate, lung, colorectal and ovarian cancer screening trial

Robert Philibert, Steven R.H. Beach, James A. Mills, Kelsey Dawes, Richard M. Hoffman, Jessica C. Sieren, Ellyse M. Froehlich, Kaitlyn M. deBlois, Jeffrey D. Long

published 22 May 2025

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Bisulphite sequencing in the presence of cytosine-conversion errors

Thomas James Ellis, Viktoria Nizhynska, Rahul Pisupati, Almudena Mollá-Morales, Magnus Nordborg

published 21 May 2025

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Hypotaurine promotes glioma cell invasion by hypermethylating the Wnt5a promoter

Hong Tian, Xiaoli Chu, Qi Guan, Juan Liu, Ying Liu

published 15 May 2025

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Noninvasive prognostication of hepatocellular carcinoma based on cell-free DNA methylation

Ran Hu, Benjamin Tran, Shuo Li, Mary L. Stackpole, Weihua Zeng, Yonggang Zhou, Andrew Melehy, Saeed Sadeghi, Richard S. Finn, Xianghong Jasmine Zhou, Wenyuan Li, Vatche G. Agopian

published 25 Apr 2025

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