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Metabolites

Integrated analysis of genome, metabolome, and transcriptome reveals a bHLH transcription factor potentially regulating the accumulation of flavonoids involved in carrot resistance to Alternaria leaf blight

Claude Emmanuel Koutouan, Marie Louisa Ramaroson, Angelina El Ghaziri, Laurent Ogé, Abdelhamid Kebieche, Raymonde Baltenweck, Patricia Claudel, Philippe Hugueney, Anita Suel, Sébastien Huet, Linda Voisine, Mathilde Briard, Jean Jacques Helesbeux, Latifa Hamama, Valérie Le Clerc, Emmanuel Geoffriau

published 19 Nov 2025

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Effects of ascorbic acid on intestinal flora and metabolites of C57 mice exposed to formaldehyde in digestive tract

Xin Ling, Ziyan Hao, Yixuan Shi, Yuting Li, Kehan Wang, Yunshan Zhang, Yue Wang

published 19 Nov 2025

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Antitumor and cytotoxic activities of endophytic Enterobacter hormaechei derived secondary metabolites: In-vitro and In-silico study

Muddasir Khan, Sumera Afzal Khan, Chieh-Wei Chang, Chien-Chin Chen, Bokyung Lee, Muhammad Hamayun

published 18 Nov 2025

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The mediating role of blood metabolites in the association between myocardial infarction and cancer risk: An observational and mendelian randomization analysis

Jia Zhu, Xiaojun Xia, Haodong Jiang, Congying Wang, Yunpeng Jin

published 14 Nov 2025

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Metabolic remodeling and cardiac dysfunction in left ventricular noncompaction: Insights from the MYH7 Q315R model

Shinya Takarada, Yukiko Hata, Keisuke Yaku, Hironori Izumi, Kazuki Fujii, Masaaki Omura, Ichiro Takasaki, Kaori Tsuboi, Mako Okabe, Nariaki Miyao, Hideyuki Nakaoka, Keijiro Ibuki, Sayaka Ozawa, Takashi Nakagawa, Hideyuki Hasegawa, Shojiro Ichimata, Naoki Nishida, Hisashi Mori, Yuko Yanagibashi, Keizo Takao, Fukiko Ichida, Keiichi Hirono

published 14 Nov 2025

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Isoflurane anesthesia alters 31P magnetic resonance spectroscopy markers compared to awake mouse brain

Saba Molhemi, Rasmus West Knopper, Christian Stald Skoven, Thomas Beck Lindhardt, Caroline Degel, Leif Østergaard, Brian Hansen

published 14 Nov 2025

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Mass spectrometry-based metabolomics uncovers distinct metabolic signatures and potential therapeutic targets in Plasmodium knowlesi

Naphatsamon Uthailak, Sadudee Chotirat, Ammarind Anatjitsupha, Waraporn Thongyod, Phornpimon Tipthara, Jetsumon Sattabongkot, Joel Tarning, Wang Nguitragool, Onrapak Reamtong

published 13 Nov 2025

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Metabolomics and glucose tolerance in pregnancy and postpartum: The PONCH study

Ulrika Andersson-Hall, Anders Bay Nord, Daniel Malmodin, Agneta Holmäng

published 07 Nov 2025

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Morphological and chemotaxonomical characterization of some species of the genus Euphorbia L. in Jazan region, KSA

Yehia Hazzazi, Mari Sumayli, A. El-Shabasy, Abeer Al-Andal, Uzma Hanif, Asmaa Khamis, Emad Abada, Sameh R. Elgogary, Taha A. I. El-Bassossy, Ahmed A. M. Abdelgawad

published 05 Nov 2025

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Metabolomics and databases driven approach of identification of phytochemicals from seed of Salvia schimperi using high-performance liquid chromatography tandem mass spectrometry

M. Azene, O. O. Olaokun, B.C. Iweriebor, N.M. Mkolo, C.L. Obi, W. Shibeshi, S. Assefa, Z. Abebe, A. Habtamu, K. Baye

published 03 Nov 2025

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In silico identification, high yielding isolation and in vitro validation of 6β-cinnamoyl-7β -hydroxyvouacapen – 5α - ol as a Wnt/β-catenin pathway targeted anti-cancer secondary metabolite of Caesalpinia pulcherrima

Nirwani N. Seneviratne, Tolulope P. Saliu, Fathima T. Muhinudeen, Sanadie D. Gamage, Prabudhi S. Garusinghe, Damith Chathuranga, Vinoda D. Athukorala, Ashein Kothalawala, Asirini H. Jayasekara, Rajitha K. Rathnayaka, Umanda Anjalee De Silva, Mohamed Faries, Thimali H. Weragoda, Shalini K. Wijerathne, Umapriyatharshini Rajagopalan, Kanishka S. Senathilake, Kamani H. Tennekoon, Achyut Adhikari, Sameera R. Samarakoon

published 03 Nov 2025

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Isolation, identification, and whole-genome sequencing of Streptomyces rochei FE-3-1 against Pyricularia oryzae

Dongxia Du, Zhuo Yi, Shiping Shan, Shuaishuai Gao, Mengyuan Yu, Bin Wang

published 29 Oct 2025

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Phytochemical characterization and anticancer potential of Psidium cattleianum Sabine aerial parts’ n-hexane extract and its subfractions

Eman M. El-Deeb, Fatma A. Moharram, Hussein S. Taha, Mohamed R. Elgindi, Kuei-Hung Lai, Hassan Y. Ebrahim, Heba E. Elsayed

published 27 Oct 2025

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