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Metabolic pathways

Multimodal analysis investigating the shared pathogenic mechanisms of osteoporosis and osteoarthritis with an initial exploration of the role of ferroptosis

Chunqing Wang, Dongcheng Ran, Wenyi Li, Cheng Yang, Weimin Li

published 25 Sep 2025

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Metabolic diversity in sorghum: Mechanism underlying grain color variation and fermentation quality

Fan Yang, Jiaqi Qiao, Miao Yang, Dongye Liu, Huimei Sun, Xinxin Wang, Xiao Zhang, Dongao Huo

published 25 Sep 2025

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Differential regulation of long noncoding RNAs by endogenous and exogenous reactive oxygen species-generating prooxidants in NIH3T3 cells

Yoichi Kurokawa, Takashi Honda, Shingo Fujii, Yugo Narisawa, Hirotaka Ogawa, Hiroki Kawashima, Hidenori Tani

published 22 Sep 2025

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Integrative transcriptomic and metabolomic analyses provide insights into the mechanism of autotoxicity of Pugionium cornutum (L.) Gaertn

Kezhen Ning, Fenglan Zhang, Zhongren Yang, Xiaoyan Zhang, Dong Zhang, Xinyuan Qin, Xiumei Huang, Lizhen Hao

published 17 Sep 2025

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Preliminary study on metabolite differences between two obesity syndromes based on Q Exactive liquid chromatography–tandem mass spectrometry metabolomics

Ye Jing, Xiaoxuan Xu, Yanhong Wang, Xue Qu, Yunlong Guo, Ao Guo, Yulin Dai, Yangyang Liu, Hao Yue

published 10 Sep 2025

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Circulating metabolites in patients with chronic heart failure are not related to gut leakage or gut dysbiosis

Andraž Nendl, Sajan C. Raju, Peder R. Braadland, Anna Nordborg, Vibeke Bratseth, Kaspar Broch, Silje F. Jørgensen, Pål Aukrust, Karsten Kristiansen, Johannes R. Hov, Marius Trøseid, Ayodeji Awoyemi

published 08 Sep 2025

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Analysis of flavor formation and metabolite changes during production of Double-Layer Steamed Milk Custard made from buffalo milk

Hong Lan, Xier Luo, Dingyun Xu, Kuiqing Cui, Ling Li, Chuan Li, Hao Qi, Qingyou Liu

published 08 Sep 2025

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Reversing metabolic dysregulation in farnesoid X receptor knockout mice via gut microbiota modulation

Ines Leila Paraiso, Armando Alcázar Magaña, Alexandra Alexiev, Thomas J. Sharpton, Claudia S. Maier, Chrissa Kioussi, Jan F. Stevens

published 05 Sep 2025

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Integrated transcriptomic and metabolomic analysis of Jinggang honey pomelo yellow spot disease to reveal the disease resistance mechanism

Huimin Sun, Zexia Li, Yongfa Guo, Weiwei Li, Biling Jin, Ling Lu, Dingkun Liu, Li He, Shuaiwen Yin, Yang Wu

published 04 Sep 2025

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New insights into the molecular biology of Alzheimer’s-like cerebral amyloidosis achieved through multi‐omics approaches

Lorenzo Campanelli, Juan M. Sendoya, Scott Brody, Pablo Galeano, Sonia Do Carmo, A. Claudio Cuello, Eduardo M. Castaño, Andrés Gonzalés-Jimenez, Julia Verheul, Dina Medina-Vera, Fernando Rodríguez de Fonseca, Rasmus Wernersson, Laura Morelli

published 03 Sep 2025

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Identification of core genes in the extracellular matrix and the regulatory mechanisms of the immune microenvironment in idiopathic pulmonary fibrosis using WGCNA and machine learning methods

Man Wang, Lu Liu, Yang Liu, Shihuan Yu

published 26 Aug 2025

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Investigating the Trichosanthis Pericarpium - Trichosanthis Radix herbal pair’s role in alleviating COPD through gut microbiota function, metabolomics analysis and cell validation experiment

Yushan Zhao, Xiaoying Tan, Tian Wang, Yuxuan Yuan, Kelei Su, Erxin Shang, Qingling Xiao, Sheng Guo, Shulan Su, Huangqin Zhang, Jin-ao Duan, Pei Liu

published 22 Aug 2025

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Fetal programming through early weaning shapes the metabotype of Nelore heifers

Anjaleena Yaseen, Ana Laura dos Santos Munhoz Gôngora, Thiago Kan Nishimura, Gabriel Henrique Ribeiro, Eduardo Solano Pina Santos, Alanne Tenório Nunes, Tarique Hussain, Amjad Hameed, Luiz Alberto Colnago, Paulo Roberto Leme, Arlindo Saran Netto, Guilherme Pugliesi, Nara Regina Brandão Cônsolo

published 22 Aug 2025

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