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Membrane potential

Electrophysiological evaluation of an anticancer drug gemcitabine on cardiotoxicity revealing down-regulation and modification of the activation gating properties in the human rapid delayed rectifier potassium channel

Mengyan Wei, Pu Wang, Xiufang Zhu, Masaki Morishima, Yangong Liu, Mingqi Zheng, Gang Liu, Hiroki Osanai, Kenshi Yoshimura, Shinichiro Kume, Tatsuki Kurokawa, Katsushige Ono

published 02 Feb 2023

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Ectodomain shedding of EGFR ligands serves as an activation readout for TRP channels

Manae Tatsumi, Takayuki Kishi, Satoru Ishida, Hiroki Kawana, Akiharu Uwamizu, Yuki Ono, Kouki Kawakami, Junken Aoki, Asuka Inoue

published 20 Jan 2023

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Spatiotemporal patterns of early afterdepolarizations underlying abnormal T-wave morphologies in a tissue model of the Purkinje-ventricular system

Mengya Yuan, Heqiang Lian, Pan Li

published 09 Jan 2023

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Quantitative assessment of depolarization by the retinal pigment epithelium in healthy and glaucoma subjects measured over a large field of view

Alice R. Motschi, Florian Schwarzhans, Sylvia Desissaire, Stefan Steiner, Hrvoje Bogunović, Philipp K. Roberts, Clemens Vass, Christoph K. Hitzenberger, Michael Pircher

published 13 Dec 2022

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Differential thalamocortical interactions in slow and fast spindle generation: A computational model

Muhammad Mushtaq, Lisa Marshall, Maxim Bazhenov, Matthias Mölle, Thomas Martinetz

published 12 Dec 2022

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Effects of subjective and objective task difficulties for feedback- related brain potentials in social situations: An electroencephalogram study

Yusuke Yokota, Yasushi Naruse

published 01 Dec 2022

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Acute heat stress-indued apoptosis in mouse skeletal muscle is not associated with alteration of glutamine homeostasis

Yifan Chen, Tianzheng Yu, Patricia A. Deuster

published 28 Nov 2022

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Experimental factors that impact Ca_V1.2 channel pharmacology—Effects of recording temperature, charge carrier, and quantification of drug effects on the step and ramp currents elicited by the “step-step-ramp” voltage protocol

Ming Ren, Aaron L. Randolph, Claudia Alvarez-Baron, Donglin Guo, Phu N. Tran, Nicolas Thiebaud, Jiansong Sheng, Jun Zhao, Wendy W. Wu

published 23 Nov 2022

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Rosemary essential oil and its components 1,8-cineole and α-pinene induce ROS-dependent lethality and ROS-independent virulence inhibition in Candida albicans

Zinnat Shahina, Raymond Al Homsi, Jared D. W. Price, Malcolm Whiteway, Taranum Sultana, Tanya E. S. Dahms

published 16 Nov 2022

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Multicenter validation of a machine learning phase space electro-mechanical pulse wave analysis to predict elevated left ventricular end diastolic pressure at the point-of-care

Sanjeev P. Bhavnani, Rola Khedraki, Travis J. Cohoon, Frederick J. Meine III, Thomas D. Stuckey, Thomas McMinn, Jeremiah P. Depta, Brett Bennett, Thomas McGarry, William Carroll, David Suh, John A. Steuter, Michael Roberts, Horace R. Gillins, Ian Shadforth, Emmanuel Lange, Abhinav Doomra, Mohammad Firouzi, Farhad Fathieh, Timothy Burton, Ali Khosousi, Shyam Ramchandani, William E. Sanders Jr., Frank Smart

published 15 Nov 2022

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Apoptosis in platelets is independent of the actin cytoskeleton

Enoli De Silva, Manoj Paul, Hugh Kim

published 15 Nov 2022

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Long-range axonal projections of transplanted mouse embryonic stem cell-derived hypothalamic neurons into adult mouse brain

Miho Kawata, Yu Kodani, Mahito Ohkuma, Ei-ichi Miyachi, Yoko S. Kaneko, Akira Nakashima, Hidetaka Suga, Toshiki Kameyama, Kanako Saito, Hiroshi Nagasaki

published 10 Nov 2022

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A modular and reusable model of epithelial transport in the proximal convoluted tubule

Leyla Noroozbabaee, Pablo J. Blanco, Soroush Safaei, David P. Nickerson

published 10 Nov 2022

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