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Major histocompatibility complex

Human responses to the DNA prime/chimpanzee adenovirus (ChAd63) boost vaccine identify CSP, AMA1 and TRAP MHC Class I-restricted epitopes

Harini Ganeshan, Jun Huang, Maria Belmonte, Arnel Belmonte, Sandra Inoue, Rachel Velasco, Santina Maiolatesi, Keith Limbach, Noelle Patterson, Marvin J. Sklar, Lorraine Soisson, Judith E. Epstein, Kimberly A. Edgel, Bjoern Peters, Michael R. Hollingdale, Eileen Villasante, Christopher A. Duplessis, Martha Sedegah

published 13 Feb 2025

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Development of a multi-epitope chimeric vaccine in silico against Babesia bovis, Theileria annulata, and Anaplasma marginale using computational biology tools and reverse vaccinology approach

Amam Zonaed Siddiki, Sabreena Alam, Farhan Fuad Bin Hossen, Md. Abdul Alim

published 24 Jan 2025

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Molecular dynamics simulation based prediction of T-cell epitopes for the production of effector molecules for liver cancer immunotherapy

Sidra Zafar, Yuhe Bai, Syed Aun Muhammad, Jinlei Guo, Haris Khurram, Saba Zafar, Iraj Muqaddas, Rehan Sadiq Shaikh, Baogang Bai

published 03 Jan 2025

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Advancing one health vaccination: In silico design and evaluation of a multi-epitope subunit vaccine against Nipah virus for cross-species immunization using immunoinformatics and molecular modeling

Edward Coralde Banico, Ella Mae Joy Sinco Sira, Lauren Emily Fajardo, Albert Neil Gura Dulay, Nyzar Mabeth Obenio Odchimar, Alea Maurice Simbulan, Fredmoore Legaspi Orosco

published 26 Sep 2024

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An integrated comparative genomics, subtractive proteomics and immunoinformatics framework for the rational design of a Pan-Salmonella multi-epitope vaccine

Arittra Bhattacharjee, Md. Rakib Hosen, Anika Bushra Lamisa, Ishtiaque Ahammad, Zeshan Mahmud Chowdhury, Tabassum Binte Jamal, Md. Mehadi Hasan Sohag, Mohammad Uzzal Hossain, Keshob Chandra Das, Chaman Ara Keya, Md Salimullah

published 03 Jul 2024

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Bioinformatics design of a peptide vaccine containing sarcoma antigen NY-SAR-35 epitopes against breast cancer and evaluation of its immunological function in BALB/c mouse model

Nour Samman, Hassan Mohabatkar, Mandana Behbahani, Mazdak Ganjlikhani Hakemi

published 26 Jun 2024

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Diversity of major histocompatibility complex of II B gene and mate choice in a monogamous and long-lived seabird, the Little Auk (Alle alle)

Katarzyna Wojczulanis-Jakubas, Brian Hoover, Dariusz Jakubas, Jérôme Fort, David Grémillet, Maria Gavrilo, Sylwia Zielińska, Magdalena Zagalska-Neubauer

published 12 Jun 2024

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GraphMHC: Neoantigen prediction model applying the graph neural network to molecular structure

Hoyeon Jeong, Young-Rae Cho, Jungsoo Gim, Seung-Kuy Cha, Maengsup Kim, Dae Ryong Kang

published 27 Mar 2024

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Computational design of experimentally validated multi-epitopes vaccine against hepatitis E virus: An immunological approach

Tasneem Anwar, Saba Ismail, Fahed Parvaiz, Sumra Wajid Abbasi, Fahad A. Al-Abbasi, Amira M. Alghamdi, Khalid Al-Regaiey, Asad Ul-Haq, Imdad Kaleem, Shahid Bashir, Yasir Waheed

published 14 Dec 2023

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Longitudinal multi-functional analysis identified responses of T cells, B cells, and monocytes as hallmarks of immunotherapy tolerance in patients with merkel cell carcinoma

Quyuan Tao, Jia-xin Du, Shijing Zhang, Wenjia Lin, Yongxin Luo, Ying Liu, Jingyan Zeng, Xin-lin Chen

published 20 Nov 2023

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Anti-inflammatory effects of cold atmospheric plasma irradiation on the THP-1 human acute monocytic leukemia cell line

Ito Hirasawa, Haruka Odagiri, Giri Park, Rutvi Sanghavi, Takaya Oshita, Akiko Togi, Katsunori Yoshikawa, Koji Mizutani, Yasuo Takeuchi, Hiroaki Kobayashi, Sayaka Katagiri, Takanori Iwata, Akira Aoki

published 18 Oct 2023

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Coarse-grained molecular dynamics-guided immunoinformatics to explain the binder and non-binder classification of Cytotoxic T-cell epitope for SARS-CoV-2 peptide-based vaccine discovery

Muhammad Yusuf, Wanda Destiarani, Wahyu Widayat, Yosua Yosua, Gilang Gumilar, Angelica Shalfani Tanudireja, Fauzian Giansyah Rohmatulloh, Farhan Azhwin Maulana, Umi Baroroh, Ari Hardianto, Rani Maharani, Neni Nurainy, Acep Riza Wijayadikusumah, Ryan B. Ristandi, Ines Irene Caterina Atmosukarto, Toto Subroto

published 05 Oct 2023

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Assessing HLA imputation accuracy in a West African population

Ruth Nanjala, Mamana Mbiyavanga, Suhaila Hashim, Santie de Villiers, Nicola Mulder

published 28 Sep 2023

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