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Library screening

CTDSP1 inhibitor rabeprazole regulates DNA-PKcs dependent topoisomerase I degradation and irinotecan drug resistance in colorectal cancer

Hiroya Matsuoka, Koji Ando, [ ... ], Masaki Mori

A cell-based high-throughput screen identifies inhibitors that overcome P-glycoprotein (Pgp)-mediated multidrug resistance

Rida Zahra, Muhammad Furqan, [ ... ], Amir Faisal

An exon skipping screen identifies antitumor drugs that are potent modulators of pre-mRNA splicing, suggesting new therapeutic applications

Yihui Shi, Walter Bray, [ ... ], Thomas R. Webb

Filaggrin and filaggrin 2 processing are linked together through skin aspartic acid protease activation

Mark Donovan, Mélanie Salamito, [ ... ], Dominique Bernard

Host interactors of effector proteins of the lettuce downy mildew Bremia lactucae obtained by yeast two-hybrid screening

Alexandra J. E. Pelgrom, Claudia-Nicole Meisrimler, [ ... ], Guido Van den Ackerveken

Protocol development for discovery of angiogenesis inhibitors via automated methods using zebrafish

Antonio Mauro, Robin Ng, [ ... ], Xiao-Yan Wen

Selection of reference genes for normalization of cranberry (Vaccinium macrocarpon Ait.) gene expression under different experimental conditions

Chen Li, Jian Xu, [ ... ], Yadong Li

Identification of variant HIV envelope proteins with enhanced affinities for precursors to anti-gp41 broadly neutralizing antibodies

Hong Zhu, Elizabeth Mathew, [ ... ], Mark E. Dumont

Computational and experimental elucidation of Plasmodium falciparum phosphoethanolamine methyltransferase inhibitors: Pivotal drug target

Jagbir Singh, Sonam Vijay, [ ... ], Arun Sharma

Screening of microRNAs controlling body fat in Drosophila melanogaster and identification of miR-969 and its target, Gr47b

William Redmond, Dylan Allen, [ ... ], Jin Seo

Progranulin deficiency leads to reduced glucocerebrosidase activity

Xiaolai Zhou, Daniel H. Paushter, [ ... ], Fenghua Hu

Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors

Thomas W. Miller, Joshua D. Amason, [ ... ], James Inglese

Anticancer compound XL765 as PI3K/mTOR dual inhibitor: A structural insight into the inhibitory mechanism using computational approaches

Mohd Rehan

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