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Library screening

Double antibody pairs sandwich-ELISA (DAPS-ELISA) detects Acidovorax citrulli serotypes with broad coverage

Orawan Himananto, Kirana Yoohat, Kannawat Danwisetkanjana, Mallika Kumpoosiri, Sombat Rukpratanporn, Yada Theppawong, Sudtida Phuengwas, Manlika Makornwattana, Ratthaphol Charlermroj, Nitsara Karoonuthaisiri, Petcharat Thummabenjapone, Nuttima Kositcharoenkul, Oraprapai Gajanandana

published 27 Aug 2020

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CTDSP1 inhibitor rabeprazole regulates DNA-PKcs dependent topoisomerase I degradation and irinotecan drug resistance in colorectal cancer

Hiroya Matsuoka, Koji Ando, Emma J. Swayze, Elizabeth C. Unan, Joseph Mathew, Quingjiang Hu, Yasuo Tsuda, Yuichiro Nakashima, Hiroshi Saeki, Eiji Oki, Ajit K. Bharti, Masaki Mori

published 07 Aug 2020

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A cell-based high-throughput screen identifies inhibitors that overcome P-glycoprotein (Pgp)-mediated multidrug resistance

Rida Zahra, Muhammad Furqan, Rahim Ullah, Aziz Mithani, Rahman Shah Zaib Saleem, Amir Faisal

published 02 Jun 2020

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An exon skipping screen identifies antitumor drugs that are potent modulators of pre-mRNA splicing, suggesting new therapeutic applications

Yihui Shi, Walter Bray, Alexander J. Smith, Wei Zhou, Joy Calaoagan, Chandraiah Lagisetti, Lidia Sambucetti, Phillip Crews, R. Scott Lokey, Thomas R. Webb

published 29 May 2020

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Filaggrin and filaggrin 2 processing are linked together through skin aspartic acid protease activation

Mark Donovan, Mélanie Salamito, Agnès Thomas-Collignon, Lucie Simonetti, Stephanie Desbouis, Jean-Christophe Rain, Etienne Formstecher, Dominique Bernard

published 21 May 2020

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Host interactors of effector proteins of the lettuce downy mildew Bremia lactucae obtained by yeast two-hybrid screening

Alexandra J. E. Pelgrom, Claudia-Nicole Meisrimler, Joyce Elberse, Thijs Koorman, Mike Boxem, Guido Van den Ackerveken

published 12 May 2020

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Protocol development for discovery of angiogenesis inhibitors via automated methods using zebrafish

Antonio Mauro, Robin Ng, Jamie Yuanjun Li, Rui Guan, Youdong Wang, Krishna Kumar Singh, Xiao-Yan Wen

published 15 Nov 2019

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Selection of reference genes for normalization of cranberry (Vaccinium macrocarpon Ait.) gene expression under different experimental conditions

Chen Li, Jian Xu, Yu Deng, Haiyue Sun, Yadong Li

published 12 Nov 2019

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Identification of variant HIV envelope proteins with enhanced affinities for precursors to anti-gp41 broadly neutralizing antibodies

Hong Zhu, Elizabeth Mathew, Sara M. Connelly, Jeffrey Zuber, Mark Sullivan, Michael S. Piepenbrink, James J. Kobie, Mark E. Dumont

published 10 Sep 2019

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Computational and experimental elucidation of Plasmodium falciparum phosphoethanolamine methyltransferase inhibitors: Pivotal drug target

Jagbir Singh, Sonam Vijay, Rani Mansuri, Ritu Rawal, Kavita Kadian, Ganesh Chandra Sahoo, Mahesh Kumar, Arun Sharma

published 22 Aug 2019

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Screening of microRNAs controlling body fat in Drosophila melanogaster and identification of miR-969 and its target, Gr47b

William Redmond, Dylan Allen, M. Christian Elledge, Russell Arellanes, Lucille Redmond, Jared Yeahquo, Shuyin Zhang, Morgan Youngblood, Austin Reiner, Jin Seo

published 18 Jul 2019

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Progranulin deficiency leads to reduced glucocerebrosidase activity

Xiaolai Zhou, Daniel H. Paushter, Mitchell D. Pagan, Dongsung Kim, Mariela Nunez Santos, Raquel L. Lieberman, Herman S. Overkleeft, Ying Sun, Marcus B. Smolka, Fenghua Hu

published 10 Jul 2019

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Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors

Thomas W. Miller, Joshua D. Amason, Elsa D. Garcin, Laurence Lamy, Patricia K. Dranchak, Ryan Macarthur, John Braisted, Jeffrey S. Rubin, Teresa L. Burgess, Catherine L. Farrell, David D. Roberts, James Inglese

published 05 Jul 2019

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