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Library screening

Nanodiscs Allow Phage Display Selection for Ligands to Non-Linear Epitopes on Membrane Proteins

Marina Pavlidou, Karen Hänel, Luis Möckel, Dieter Willbold

Generation of a Genome Scale Lentiviral Vector Library for EF1α Promoter-Driven Expression of Human ORFs and Identification of Human Genes Affecting Viral Titer

Dubravka Škalamera, Mareike Dahmer, [ ... ], Thomas J. Gonda

Alternative Computational Protocols for Supercharging Protein Surfaces for Reversible Unfolding and Retention of Stability

Bryan S. Der, Christien Kluwe, [ ... ], Brian Kuhlman

Transposon insertion libraries for the characterization of mutants from the kiwifruit pathogen Pseudomonas syringae pv. actinidiae

Carl H. Mesarich, Jonathan Rees-George, [ ... ], Matthew D. Templeton

Transposon Mutagenesis in Bifidobacterium breve: Construction and Characterization of a Tn5 Transposon Mutant Library for Bifidobacterium breve UCC2003

Lorena Ruiz, Mary O’Connell Motherway, Noreen Lanigan, Douwe van Sinderen

A Novel Malate Dehydrogenase 2 Inhibitor Suppresses Hypoxia-Inducible Factor-1 by Regulating Mitochondrial Respiration

Hyun Seung Ban, Xuezhen Xu, [ ... ], Misun Won

Genes Important for Catalase Activity in Enterococcus faecalis

Michael Baureder, Lars Hederstedt

Enabling Large-Scale Design, Synthesis and Validation of Small Molecule Protein-Protein Antagonists

David Koes, Kareem Khoury, [ ... ], Carlos J. Camacho

Target discovery screens using pooled shRNA libraries and next-generation sequencing: A model workflow and analytical algorithm

Christiane Schaefer, Nikhil Mallela, [ ... ], Jenny Potratz

Identification of Highly Selective and Potent Histone Deacetylase 3 Inhibitors Using Click Chemistry-Based Combinatorial Fragment Assembly

Takayoshi Suzuki, Yuki Kasuya, [ ... ], Naoki Miyata

SPR-based fragment screening with neurotensin receptor 1 generates novel small molecule ligands

Sylwia Huber, Fabio Casagrande, [ ... ], Michael Hennig

High Throughput Screening for Small Molecule Therapy for Gaucher Disease Using Patient Tissue as the Source of Mutant Glucocerebrosidase

Ehud Goldin, Wei Zheng, [ ... ], Ellen Sidransky

High-throughput Screening and Sensitized Bacteria Identify an M. tuberculosis Dihydrofolate Reductase Inhibitor with Whole Cell Activity

Anuradha Kumar, Meng Zhang, [ ... ], Ming-Wei Wang

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