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Library screening

Substitutional landscape of a split fluorescent protein fragment using high-density peptide microarrays

Oana N. Antonescu, Andreas Rasmussen, Nicole A. M. Damm, Ditte F. Heidemann, Roman Popov, Alexander Nesterov-Mueller, Kristoffer E. Johansson, Jakob R. Winther

published 03 Feb 2021

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A drug repurposing screen identifies hepatitis C antivirals as inhibitors of the SARS-CoV2 main protease

Jeremy D. Baker, Rikki L. Uhrich, Gerald C. Kraemer, Jason E. Love, Brian C. Kraemer

published 01 Feb 2021

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Identification of Prostaglandin F2 Receptor Negative Regulator (PTGFRN) as an internalizable target in cancer cells for antibody-drug conjugate development

Jorge Marquez, Jianping Dong, Chun Dong, Changsheng Tian, Ginette Serrero

published 27 Jan 2021

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Functional screening of a Caatinga goat (Capra hircus) rumen metagenomic library reveals a novel GH3 β-xylosidase

Betulia de Morais Souto, Ana Carolina Bitencourt de Araújo, Pedro Ricardo Vieira Hamann, Andrêssa de Rezende Bastos, Isabel de Souza Cunha, Julianna Peixoto, Ricardo Henrique Kruger, Eliane Ferreira Noronha, Betania Ferraz Quirino

published 15 Jan 2021

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Development of an orally-administrable tumor vasculature-targeting therapeutic using annexin A1-binding D-peptides

Motohiro Nonaka, Hideaki Mabashi-Asazuma, Donald L. Jarvis, Kazuhiko Yamasaki, Tomoya O. Akama, Masato Nagaoka, Toshio Sasai, Itsuko Kimura-Takagi, Yoichi Suwa, Takashi Yaegashi, Chun-Teng Huang, Chizuko Nishizawa-Harada, Michiko N. Fukuda

published 06 Jan 2021

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Potency of Tokishakuyakusan in treating preeclampsia: Drug repositioning method by in vitro screening of the Kampo library

Kazunobu Yagi, Kazuya Mimura, Takuji Tomimatsu, Tatsuya Matsuyama, Yoko Kawanishi, Aiko Kakigano, Hitomi Nakamura, Masayuki Endo, Tadashi Kimura

published 30 Dec 2020

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Image-based screen capturing misfolding status of Niemann-Pick type C1 identifies potential candidates for chaperone drugs

Ryuta Shioi, Fumika Karaki, Hiromasa Yoshioka, Tomomi Noguchi-Yachide, Minoru Ishikawa, Kosuke Dodo, Yuichi Hashimoto, Mikiko Sodeoka, Kenji Ohgane

published 14 Dec 2020

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Chlamydomonas reinhardtii tubulin-gene disruptants for efficient isolation of strains bearing tubulin mutations

Takako Kato-Minoura, Yutaro Ogiwara, Takashi Yamano, Hideya Fukuzawa, Ritsu Kamiya

published 23 Nov 2020

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How to perform spectrum-based LC-HR-MS screening for more than 1,000 NPS with HighResNPS consensus fragment ions

Anders Davidsen, Marie Mardal, Kristian Linnet, Petur Weihe Dalsgaard

published 12 Nov 2020

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Horizontal genetic exchange of chromosomally encoded markers between Campylobacter jejuni cells

Deepti Pranay Samarth, Young Min Kwon

published 26 Oct 2020

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Identification of two potential inhibitors of Sporothrix brasiliensis and Sporothrix schenckii in the Pathogen Box collection

Luana Pereira Borba-Santos, Taissa Vila, Sonia Rozental

published 14 Oct 2020

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Assessing multiple score functions in Rosetta for drug discovery

Shannon T. Smith, Jens Meiler

published 12 Oct 2020

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Biochemical screening for SARS-CoV-2 main protease inhibitors

Camila Coelho, Gloria Gallo, Claudia B. Campos, Leon Hardy, Martin Würtele

published 06 Oct 2020

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