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Library screening

Local occurrence and fast spread of B.1.1.7 lineage: A glimpse into Friuli Venezia Giulia

Catia Mio, Chiara Dal Secco, Stefania Marzinotto, Claudio Bruno, Santa Pimpo, Elena Betto, Martina Bertoni, Corrado Pipan, Emanuela Sozio, Carlo Tascini, Giuseppe Damante, Francesco Curcio

published 14 Dec 2021

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Fucosyltransferase 2 inhibitors: Identification via docking and STD-NMR studies

Humaira Zafar, Muhammad Atif, Atia-tul-Wahab, M. Iqbal Choudhary

published 14 Oct 2021

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Neuroinductive properties of mGDNF depend on the producer, E. Coli or human cells

Dzhirgala V. Shamadykova, Dmitry Y. Panteleev, Nadezhda N. Kust, Ekaterina A. Savchenko, Ekaterina Y. Rybalkina, Alexander V. Revishchin, Galina V. Pavlova

published 11 Oct 2021

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Dabrafenib, idelalisib and nintedanib act as significant allosteric modulator for dengue NS3 protease

R. V. Sriram Uday, Rajdip Misra, Annaram Harika, Sandip Dolui, Achintya Saha, Uttam Pal, V. Ravichandiran, Nakul C. Maiti

published 10 Sep 2021

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The effect of librarian involvement on the quality of systematic reviews in dental medicine

Jana Schellinger, Kerry Sewell, Jamie E. Bloss, Tristan Ebron, Carrie Forbes

published 01 Sep 2021

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CDK4/6 inhibition synergizes with inhibition of P21-Activated Kinases (PAKs) in lung cancer cell lines

Gabriela M. Wright, Nick T. Gimbrone, Bhaswati Sarcar, Trent R. Percy, Edna R. Gordián, Fumi Kinose, Natália J. Sumi, Uwe Rix, W. Douglas Cress

published 17 Jun 2021

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Evaluation of Hsp90 and mTOR inhibitors as potential drugs for the treatment of TSC1/TSC2 deficient cancer

Evelyn M. Mrozek, Vineeta Bajaj, Yanan Guo, Izabela A. Malinowska, Jianming Zhang, David J. Kwiatkowski

published 23 Apr 2021

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4-(2,5-Dimethyl-1H-pyrrol-1-yl)-N-(2,5-dioxopyrrolidin-1-yl) benzamide improves monoclonal antibody production in a Chinese hamster ovary cell culture

Yuichi Aki, Yuta Katsumata, Hirofumi Kakihara, Koichi Nonaka, Kenshu Fujiwara

published 22 Apr 2021

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High-throughput screening of the ReFRAME, Pandemic Box, and COVID Box drug repurposing libraries against SARS-CoV-2 nsp15 endoribonuclease to identify small-molecule inhibitors of viral activity

Ryan Choi, Mowei Zhou, Roger Shek, Jesse W. Wilson, Logan Tillery, Justin K. Craig, Indraneel A. Salukhe, Sarah E. Hickson, Neeraj Kumar, Rhema M. James, Garry W. Buchko, Ruilian Wu, Sydney Huff, Tu-Trinh Nguyen, Brett L. Hurst, Sara Cherry, Lynn K. Barrett, Jennifer L. Hyde, Wesley C. Van Voorhis

published 22 Apr 2021

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Selective killing of homologous recombination-deficient cancer cell lines by inhibitors of the RPA:RAD52 protein-protein interaction

Mona Al-Mugotir, Jeffrey J. Lovelace, Joseph George, Mika Bessho, Dhananjaya Pal, Lucas Struble, Carol Kolar, Sandeep Rana, Amarnath Natarajan, Tadayoshi Bessho, Gloria E. O. Borgstahl

published 30 Mar 2021

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Drug screening to identify compounds to act as co-therapies for the treatment of Burkholderia species

Sam Barker, Sarah V. Harding, David Gray, Mark I. Richards, Helen S. Atkins, Nicholas J. Harmer

published 25 Mar 2021

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A “ligand-targeting” peptide-drug conjugate: Targeted intracellular drug delivery by VEGF-binding helix-loop-helix peptides via receptor-mediated endocytosis

Masataka Michigami, Kentaro Takahashi, Haruna Yamashita, Zhengmao Ye, Ikuhiko Nakase, Ikuo Fujii

published 25 Feb 2021

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Mapping major SARS-CoV-2 drug targets and assessment of druggability using computational fragment screening: Identification of an allosteric small-molecule binding site on the Nsp13 helicase

Matthew R. Freidel, Roger S. Armen

published 17 Feb 2021

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