Advertisement

Browse Subject Areas

?

Click through the PLOS taxonomy to find articles in your field.

For more information about PLOS Subject Areas, click here.

Library screening

CDK4/6 inhibition synergizes with inhibition of P21-Activated Kinases (PAKs) in lung cancer cell lines

Gabriela M. Wright, Nick T. Gimbrone, [ ... ], W. Douglas Cress

Evaluation of Hsp90 and mTOR inhibitors as potential drugs for the treatment of TSC1/TSC2 deficient cancer

Evelyn M. Mrozek, Vineeta Bajaj, [ ... ], David J. Kwiatkowski

4-(2,5-Dimethyl-1H-pyrrol-1-yl)-N-(2,5-dioxopyrrolidin-1-yl) benzamide improves monoclonal antibody production in a Chinese hamster ovary cell culture

Yuichi Aki, Yuta Katsumata, [ ... ], Kenshu Fujiwara

High-throughput screening of the ReFRAME, Pandemic Box, and COVID Box drug repurposing libraries against SARS-CoV-2 nsp15 endoribonuclease to identify small-molecule inhibitors of viral activity

Ryan Choi, Mowei Zhou, [ ... ], Wesley C. Van Voorhis

Selective killing of homologous recombination-deficient cancer cell lines by inhibitors of the RPA:RAD52 protein-protein interaction

Mona Al-Mugotir, Jeffrey J. Lovelace, [ ... ], Gloria E. O. Borgstahl

Drug screening to identify compounds to act as co-therapies for the treatment of Burkholderia species

Sam Barker, Sarah V. Harding, [ ... ], Nicholas J. Harmer

A “ligand-targeting” peptide-drug conjugate: Targeted intracellular drug delivery by VEGF-binding helix-loop-helix peptides via receptor-mediated endocytosis

Masataka Michigami, Kentaro Takahashi, [ ... ], Ikuo Fujii

Mapping major SARS-CoV-2 drug targets and assessment of druggability using computational fragment screening: Identification of an allosteric small-molecule binding site on the Nsp13 helicase

Matthew R. Freidel, Roger S. Armen

Substitutional landscape of a split fluorescent protein fragment using high-density peptide microarrays

Oana N. Antonescu, Andreas Rasmussen, [ ... ], Jakob R. Winther

A drug repurposing screen identifies hepatitis C antivirals as inhibitors of the SARS-CoV2 main protease

Jeremy D. Baker, Rikki L. Uhrich, [ ... ], Brian C. Kraemer

Identification of Prostaglandin F2 Receptor Negative Regulator (PTGFRN) as an internalizable target in cancer cells for antibody-drug conjugate development

Jorge Marquez, Jianping Dong, [ ... ], Ginette Serrero

Functional screening of a Caatinga goat (Capra hircus) rumen metagenomic library reveals a novel GH3 β-xylosidase

Betulia de Morais Souto, Ana Carolina Bitencourt de Araújo, [ ... ], Betania Ferraz Quirino

Development of an orally-administrable tumor vasculature-targeting therapeutic using annexin A1-binding D-peptides

Motohiro Nonaka, Hideaki Mabashi-Asazuma, [ ... ], Michiko N. Fukuda

Advertisement

Create a weekly email alert for: Library screening

You can change these options by clicking profile then "Alerts and Notifications"