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Library screening

A Lentivirus-Mediated Genetic Screen Identifies Dihydrofolate Reductase (DHFR) as a Modulator of β-Catenin/GSK3 Signaling

Richard A. Klinghoffer, Jason Frazier, [ ... ], Michele A. Cleary

Negative Regulators of Insulin Signaling Revealed in a Genome-Wide Functional Screen

Shih-Min A. Huang, Michael K. Hancock, [ ... ], Nicholas Gekakis

Pharmacological Targeting of Native CatSper Channels Reveals a Required Role in Maintenance of Sperm Hyperactivation

Anne E. Carlson, Lindsey A. Burnett, [ ... ], Donner F. Babcock

Development of a Quantitative Bead Capture Assay for Soluble IL-7 Receptor Alpha in Human Plasma

Sylvie Faucher, Angela M. Crawley, [ ... ], Paul Sandstrom

CK2 Is the Regulator of SIRT1 Substrate-Binding Affinity, Deacetylase Activity and Cellular Response to DNA-Damage

Hyeog Kang, Jae-Won Jung, Myung K. Kim, Jay H. Chung

Identification of a Putative Crf Splice Variant and Generation of Recombinant Antibodies for the Specific Detection of Aspergillus fumigatus

Mark Schütte, Philippe Thullier, [ ... ], Stefan Dübel

3D Model of Lamprey Estrogen Receptor with Estradiol and 15α-Hydroxy-Estradiol

Michael E. Baker, David J. Chang, Charlie Chandsawangbhuwana

Identification and Characterization of Inhibitors of Human Apurinic/apyrimidinic Endonuclease APE1

Anton Simeonov, Avanti Kulkarni, [ ... ], David M. Wilson III

Interfering with Glycolysis Causes Sir2-Dependent Hyper-Recombination of Saccharomyces cerevisiae Plasmids

Markus Ralser, Ute Zeidler, Hans Lehrach

Small-Molecule Activators of Insulin-Degrading Enzyme Discovered through High-Throughput Compound Screening

Christelle Cabrol, Malwina A. Huzarska, [ ... ], Malcolm A. Leissring

In Vitro Recombination Catalyzed by Bacterial Class 1 Integron Integrase IntI1 Involves Cooperative Binding and Specific Oligomeric Intermediates

Véronique Dubois, Carole Debreyer, Claudine Quentin, Vincent Parissi

Successful Expansion but Not Complete Restriction of Tropism of Adeno-Associated Virus by In Vivo Biopanning of Random Virus Display Peptide Libraries

Stefan Michelfelder, Johannes Kohlschütter, [ ... ], Martin Trepel

A Conserved Mechanism for Control of Human and Mouse Embryonic Stem Cell Pluripotency and Differentiation by Shp2 Tyrosine Phosphatase

Dongmei Wu, Yuhong Pang, [ ... ], Gen-Sheng Feng

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