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Library screening

A Lentivirus-Mediated Genetic Screen Identifies Dihydrofolate Reductase (DHFR) as a Modulator of β-Catenin/GSK3 Signaling

Richard A. Klinghoffer, Jason Frazier, James Annis, Jason D. Berndt, Brian S. Roberts, William T. Arthur, Raul Lacson, Xiaohua Douglas Zhang, Marc Ferrer, Randall T. Moon, Michele A. Cleary

published 03 Sep 2009

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Negative Regulators of Insulin Signaling Revealed in a Genome-Wide Functional Screen

Shih-Min A. Huang, Michael K. Hancock, Jeffrey L. Pitman, Anthony P. Orth, Nicholas Gekakis

published 03 Sep 2009

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Pharmacological Targeting of Native CatSper Channels Reveals a Required Role in Maintenance of Sperm Hyperactivation

Anne E. Carlson, Lindsey A. Burnett, Donato del Camino, Timothy A. Quill, Bertil Hille, Jayhong A. Chong, Magdalene M. Moran, Donner F. Babcock

published 31 Aug 2009

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Development of a Quantitative Bead Capture Assay for Soluble IL-7 Receptor Alpha in Human Plasma

Sylvie Faucher, Angela M. Crawley, Wendy Decker, Alice Sherring, Dragica Bogdanovic, Tao Ding, Michele Bergeron, Jonathan B. Angel, Paul Sandstrom

published 19 Aug 2009

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CK2 Is the Regulator of SIRT1 Substrate-Binding Affinity, Deacetylase Activity and Cellular Response to DNA-Damage

Hyeog Kang, Jae-Won Jung, Myung K. Kim, Jay H. Chung

published 14 Aug 2009

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Identification of a Putative Crf Splice Variant and Generation of Recombinant Antibodies for the Specific Detection of Aspergillus fumigatus

Mark Schütte, Philippe Thullier, Thibaut Pelat, Xenia Wezler, Philip Rosenstock, Dominik Hinz, Martina Inga Kirsch, Mike Hasenberg, Ronald Frank, Thomas Schirrmann, Matthias Gunzer, Michael Hust, Stefan Dübel

published 13 Aug 2009

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3D Model of Lamprey Estrogen Receptor with Estradiol and 15α-Hydroxy-Estradiol

Michael E. Baker, David J. Chang, Charlie Chandsawangbhuwana

published 25 Jun 2009

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Identification and Characterization of Inhibitors of Human Apurinic/apyrimidinic Endonuclease APE1

Anton Simeonov, Avanti Kulkarni, Dorjbal Dorjsuren, Ajit Jadhav, Min Shen, Daniel R. McNeill, Christopher P. Austin, David M. Wilson III

published 01 Jun 2009

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Interfering with Glycolysis Causes Sir2-Dependent Hyper-Recombination of Saccharomyces cerevisiae Plasmids

Markus Ralser, Ute Zeidler, Hans Lehrach

published 24 Apr 2009

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Small-Molecule Activators of Insulin-Degrading Enzyme Discovered through High-Throughput Compound Screening

Christelle Cabrol, Malwina A. Huzarska, Christopher Dinolfo, Maria C. Rodriguez, Lael Reinstatler, Jake Ni, Li-An Yeh, Gregory D. Cuny, Ross L. Stein, Dennis J. Selkoe, Malcolm A. Leissring

published 22 Apr 2009

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In Vitro Recombination Catalyzed by Bacterial Class 1 Integron Integrase IntI1 Involves Cooperative Binding and Specific Oligomeric Intermediates

Véronique Dubois, Carole Debreyer, Claudine Quentin, Vincent Parissi

published 21 Apr 2009

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Successful Expansion but Not Complete Restriction of Tropism of Adeno-Associated Virus by In Vivo Biopanning of Random Virus Display Peptide Libraries

Stefan Michelfelder, Johannes Kohlschütter, Alexandra Skorupa, Sabrina Pfennings, Oliver Müller, Jürgen A. Kleinschmidt, Martin Trepel

published 09 Apr 2009

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A Conserved Mechanism for Control of Human and Mouse Embryonic Stem Cell Pluripotency and Differentiation by Shp2 Tyrosine Phosphatase

Dongmei Wu, Yuhong Pang, Yuehai Ke, Jianxiu Yu, Zhao He, Lutz Tautz, Tomas Mustelin, Sheng Ding, Ziwei Huang, Gen-Sheng Feng

published 17 Mar 2009

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