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Library screening

Mutational Analysis of Highly Conserved Residues in the Phage PhiC31 Integrase Reveals Key Amino Acids Necessary for the DNA Recombination

Shaohui Liu, Jinfang Ma, Wei Wang, Maoxiang Zhang, Qingting Xin, Siman Peng, Rongxiu Li, Huanzhang Zhu

published 25 Jan 2010

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Discovery of Novel Proteasome Inhibitors Using a High-Content Cell-Based Screening System

Irena Lavelin, Avital Beer, Zvi Kam, Varda Rotter, Moshe Oren, Ami Navon, Benjamin Geiger

published 30 Dec 2009

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Efficient Assembly and Secretion of Recombinant Subviral Particles of the Four Dengue Serotypes Using Native prM and E Proteins

Pei-Gang Wang, Mateusz Kudelko, Joanne Lo, Lewis Yu Lam Siu, Kevin Tsz Hin Kwok, Martin Sachse, John M. Nicholls, Roberto Bruzzone, Ralf M. Altmeyer, Béatrice Nal

published 15 Dec 2009

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Generation and Characterization of Fmr1 Knockout Zebrafish

Marjo J. den Broeder, Herma van der Linde, Judith R. Brouwer, Ben A. Oostra, Rob Willemsen, René F. Ketting

published 19 Nov 2009

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A Protein-Protein Interaction Map of the Trypanosoma brucei Paraflagellar Rod

Sylvain Lacomble, Neil Portman, Keith Gull

published 03 Nov 2009

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Versatile Assays for High Throughput Screening for Activators or Inhibitors of Intracellular Proteases and Their Cellular Regulators

Hideki Hayashi, Michael Cuddy, Vincent Chih-Wen Shu, Kenneth W. Yip, Charitha Madiraju, Paul Diaz, Toshifumi Matsuyama, Muneshige Kaibara, Kohtaro Taniyama, Stefan Vasile, Eduard Sergienko, John C. Reed

published 30 Oct 2009

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Heme Mediates Cytotoxicity from Artemisinin and Serves as a General Anti-Proliferation Target

Shiming Zhang, Glenn S. Gerhard

published 28 Oct 2009

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Structural Basis for Substrate Specificity in Human Monomeric Carbonyl Reductases

Ewa S. Pilka, Frank H. Niesen, Wen Hwa Lee, Yasser El-Hawari, James E. Dunford, Grazyna Kochan, Vladimir Wsol, Hans-Joerg Martin, Edmund Maser, Udo Oppermann

published 20 Oct 2009

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NSC23925, Identified in a High-Throughput Cell-Based Screen, Reverses Multidrug Resistance

Zhenfeng Duan, Edwin Choy, Francis J. Hornicek

published 12 Oct 2009

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Insights into the Molecular Basis of L-Form Formation and Survival in Escherichia coli

William A. Glover, Yanqin Yang, Ying Zhang

published 06 Oct 2009

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An Intermittent Live Cell Imaging Screen for siRNA Enhancers and Suppressors of a Kinesin-5 Inhibitor

Melody Tsui, Tiao Xie, James D. Orth, Anne E. Carpenter, Stewart Rudnicki, Suejong Kim, Caroline E. Shamu, Timothy J. Mitchison

published 05 Oct 2009

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RNAi Screening in Drosophila Cells Identifies New Modifiers of Mutant Huntingtin Aggregation

Joanna Doumanis, Koji Wada, Yoshihiro Kino, Adrian W. Moore, Nobuyuki Nukina

published 30 Sep 2009

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A High-Throughput Approach for Identification of Novel General Anesthetics

Wendy A. Lea, Jin Xi, Ajit Jadhav, Louis Lu, Christopher P. Austin, Anton Simeonov, Roderic G. Eckenhoff

published 24 Sep 2009

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