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Library screening

A Screen for Kinetochore-Microtubule Interaction Inhibitors Identifies Novel Antitubulin Compounds

Emanuela Screpanti, Stefano Santaguida, [ ... ], Peter De Wulf

Protein-Protein Interaction Antagonists as Novel Inhibitors of Non-Canonical Polyubiquitylation

Johanna Scheper, Marta Guerra-Rebollo, [ ... ], Timothy M. Thomson

Transmembrane and Ubiquitin-Like Domain Containing 1 (Tmub1) Regulates Locomotor Activity and Wakefulness in Mice and Interacts with CAMLG

Wandong Zhang, Katerina V. Savelieva, [ ... ], Gui-Lan Ye

Discovery of High-Affinity Protein Binding Ligands – Backwards

Chris W. Diehnelt, Miti Shah, [ ... ], Stephen Albert Johnston

Characterization of the Raf Kinase Inhibitory Protein (RKIP) Binding Pocket: NMR-Based Screening Identifies Small-Molecule Ligands

Anne N. Shemon, Gary L. Heil, [ ... ], Shohei Koide

Secreted Mycobacterium tuberculosis Rv3654c and Rv3655c Proteins Participate in the Suppression of Macrophage Apoptosis

Lia Danelishvili, Yoshitaka Yamazaki, Jeannie Selker, Luiz E. Bermudez

Binding-Site Assessment by Virtual Fragment Screening

Niu Huang, Matthew P. Jacobson

Discovery of Fragment Molecules That Bind the Human Peroxiredoxin 5 Active Site

Sarah Barelier, Dominique Linard, [ ... ], Isabelle Krimm

Novel HIV-1 Knockdown Targets Identified by an Enriched Kinases/Phosphatases shRNA Library Using a Long-Term Iterative Screen in Jurkat T-Cells

Sylvie Rato, Sara Maia, [ ... ], Joao Goncalves

Mutational Analysis of Highly Conserved Residues in the Phage PhiC31 Integrase Reveals Key Amino Acids Necessary for the DNA Recombination

Shaohui Liu, Jinfang Ma, [ ... ], Huanzhang Zhu

Discovery of Novel Proteasome Inhibitors Using a High-Content Cell-Based Screening System

Irena Lavelin, Avital Beer, [ ... ], Benjamin Geiger

Efficient Assembly and Secretion of Recombinant Subviral Particles of the Four Dengue Serotypes Using Native prM and E Proteins

Pei-Gang Wang, Mateusz Kudelko, [ ... ], Béatrice Nal

Generation and Characterization of Fmr1 Knockout Zebrafish

Marjo J. den Broeder, Herma van der Linde, [ ... ], René F. Ketting

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