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Library screening

Novel carbon skeletons activate human NicotinAMide Phosphoribosyl Transferase (NAMPT) enzyme in biochemical assay

Karen H. Almeida, Lisbeth Avalos-Irving, [ ... ], Silvia Yanez

Characterizing the consensus residue specificity and surface of BCL-2 binding to BH3 ligands using the Knob-Socket model

Jennifer Yi, Vivian Kellner, [ ... ], Jerry Tsai

Pandemic Response Box^® library as a source of antifungal drugs against Scedosporium and Lomentospora species

Rodrigo Rollin-Pinheiro, Mariana Ingrid Dutra da Silva Xisto, [ ... ], Eliana Barreto-Bergter

Repositioning of anti-dengue compounds against SARS-CoV-2 as viral polyprotein processing inhibitor

Leena H. Bajrai, Arwa A. Faizo, [ ... ], Esam I. Azhar

Identification of a novel CDK9 inhibitor targeting the intramolecular hidden cavity of CDK9 induced by Tat binding

Kaori Asamitsu, Takatsugu Hirokawa, Takashi Okamoto

Discovery of a novel natural product inhibitor of Clostridioides difficile with potent activity in vitro and in vivo

Rusha Pal, Mohamed N. Seleem

A bacterial dual positive and negative selection system for dCas9 activity

Shaun Spisak, Brett O’Brien, Marc Ostermeier

The use of a chimeric antigen for Plasmodium falciparum and P. vivax seroprevalence estimates from community surveys in Ethiopia and Costa Rica

Jessica N. McCaffery, Balwan Singh, [ ... ], Eric Rogier

Aurintricarboxylic acid is a canonical disruptor of the TAZ-TEAD transcriptional complex

Kepeng Che, Ajaybabu V. Pobbati, [ ... ], Brian P. Rubin

Development of mAb-based polyglutamine-dependent and polyglutamine length-independent huntingtin quantification assays with cross-site validation

David F. Fischer, Sipke Dijkstra, [ ... ], Douglas Macdonald

A platform of assays for the discovery of anti-Zika small-molecules with activity in a 3D-bioprinted outer-blood-retina model

Dorjbal Dorjsuren, Richard T. Eastman, [ ... ], Anton Simeonov

Evaluation of Xa inhibitors as potential inhibitors of the SARS-CoV-2 Mpro protease

Katarzyna Papaj, Patrycja Spychalska, [ ... ], Artur Góra

Local occurrence and fast spread of B.1.1.7 lineage: A glimpse into Friuli Venezia Giulia

Catia Mio, Chiara Dal Secco, [ ... ], Francesco Curcio

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