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Library screening

Identification of a novel CDK9 inhibitor targeting the intramolecular hidden cavity of CDK9 induced by Tat binding

Kaori Asamitsu, Takatsugu Hirokawa, Takashi Okamoto

published 15 Nov 2022

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Discovery of a novel natural product inhibitor of Clostridioides difficile with potent activity in vitro and in vivo

Rusha Pal, Mohamed N. Seleem

published 08 Aug 2022

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A bacterial dual positive and negative selection system for dCas9 activity

Shaun Spisak, Brett O’Brien, Marc Ostermeier

published 03 Jun 2022

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The use of a chimeric antigen for Plasmodium falciparum and P. vivax seroprevalence estimates from community surveys in Ethiopia and Costa Rica

Jessica N. McCaffery, Balwan Singh, Douglas Nace, Ashenafi Assefa, Jimee Hwang, Mateusz Plucinski, Nidia Calvo, Alberto Moreno, Venkatachalam Udhayakumar, Eric Rogier

published 25 May 2022

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Aurintricarboxylic acid is a canonical disruptor of the TAZ-TEAD transcriptional complex

Kepeng Che, Ajaybabu V. Pobbati, Caleb N. Seavey, Yuriy Fedorov, Anton A. Komar, Ashley Burtscher, Shuang Ma, Brian P. Rubin

published 13 Apr 2022

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Development of mAb-based polyglutamine-dependent and polyglutamine length-independent huntingtin quantification assays with cross-site validation

David F. Fischer, Sipke Dijkstra, Kimberly Lo, Johnny Suijker, Ana C. P. Correia, Patricia Naud, Martin Poirier, Michela A. Tessari, Ivette Boogaard, Geraldine Flynn, Mijke Visser, Marieke B. A. C. Lamers, George McAllister, Ignacio Munoz-Sanjuan, Douglas Macdonald

published 08 Apr 2022

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A platform of assays for the discovery of anti-Zika small-molecules with activity in a 3D-bioprinted outer-blood-retina model

Dorjbal Dorjsuren, Richard T. Eastman, Min Jae Song, Adam Yasgar, Yuchi Chen, Kapil Bharti, Alexey V. Zakharov, Ajit Jadhav, Marc Ferrer, Pei-Yong Shi, Anton Simeonov

published 18 Jan 2022

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Evaluation of Xa inhibitors as potential inhibitors of the SARS-CoV-2 Mpro protease

Katarzyna Papaj, Patrycja Spychalska, Patryk Kapica, André Fischer, Jakub Nowak, Maria Bzówka, Manuel Sellner, Markus A. Lill, Martin Smieško, Artur Góra

published 11 Jan 2022

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Local occurrence and fast spread of B.1.1.7 lineage: A glimpse into Friuli Venezia Giulia

Catia Mio, Chiara Dal Secco, Stefania Marzinotto, Claudio Bruno, Santa Pimpo, Elena Betto, Martina Bertoni, Corrado Pipan, Emanuela Sozio, Carlo Tascini, Giuseppe Damante, Francesco Curcio

published 14 Dec 2021

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Fucosyltransferase 2 inhibitors: Identification via docking and STD-NMR studies

Humaira Zafar, Muhammad Atif, Atia-tul-Wahab, M. Iqbal Choudhary

published 14 Oct 2021

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Neuroinductive properties of mGDNF depend on the producer, E. Coli or human cells

Dzhirgala V. Shamadykova, Dmitry Y. Panteleev, Nadezhda N. Kust, Ekaterina A. Savchenko, Ekaterina Y. Rybalkina, Alexander V. Revishchin, Galina V. Pavlova

published 11 Oct 2021

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Dabrafenib, idelalisib and nintedanib act as significant allosteric modulator for dengue NS3 protease

R. V. Sriram Uday, Rajdip Misra, Annaram Harika, Sandip Dolui, Achintya Saha, Uttam Pal, V. Ravichandiran, Nakul C. Maiti

published 10 Sep 2021

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The effect of librarian involvement on the quality of systematic reviews in dental medicine

Jana Schellinger, Kerry Sewell, Jamie E. Bloss, Tristan Ebron, Carrie Forbes

published 01 Sep 2021

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