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Library screening

High-Affinity Inhibitors of Human NAD⁺-Dependent 15-Hydroxyprostaglandin Dehydrogenase: Mechanisms of Inhibition and Structure-Activity Relationships

Frank H. Niesen, Lena Schultz, [ ... ], Anton Simeonov

Novel HTS Strategy Identifies TRAIL-Sensitizing Compounds Acting Specifically Through the Caspase-8 Apoptotic Axis

Darren Finlay, Robyn D. Richardson, [ ... ], Kristiina Vuori

Identification of the Essential Brucella melitensis Porin Omp2b as a Suppressor of Bax-Induced Cell Death in Yeast in a Genome-Wide Screening

Géraldine Laloux, Michaël Deghelt, [ ... ], Xavier De Bolle

Functional Metagenomics: A High Throughput Screening Method to Decipher Microbiota-Driven NF-κB Modulation in the Human Gut

Omar Lakhdari, Antonietta Cultrone, [ ... ], Hervé M. Blottière

Identification of Novel p53 Pathway Activating Small-Molecule Compounds Reveals Unexpected Similarities with Known Therapeutic Agents

Karita Peltonen, Laureen Colis, [ ... ], Marikki Laiho

A Multi-Parameter, High-Content, High-Throughput Screening Platform to Identify Natural Compounds that Modulate Insulin and Pdx1 Expression

Jessica A. Hill, Marta Szabat, [ ... ], James D. Johnson

Serum Stabilities of Short Tryptophan- and Arginine-Rich Antimicrobial Peptide Analogs

Leonard T. Nguyen, Johnny K. Chau, [ ... ], Hans J. Vogel

Identifying Regulators for EAG1 Channels with a Novel Electrophysiology and Tryptophan Fluorescence Based Screen

Tinatin I. Brelidze, Anne E. Carlson, [ ... ], William N. Zagotta

Ctr2 Links Copper Homeostasis to Polysaccharide Capsule Formation and Phagocytosis Inhibition in the Human Fungal Pathogen Cryptococcus neoformans

Cheryl D. Chun, Hiten D. Madhani

Cheminformatics-Based Drug Design Approach for Identification of Inhibitors Targeting the Characteristic Residues of MMP-13 Hemopexin Domain

Roopa Kothapalli, Asif M. Khan, [ ... ], Loganath Annamalai

Identification of a Cardiac Specific Protein Transduction Domain by In Vivo Biopanning Using a M13 Phage Peptide Display Library in Mice

Maliha Zahid, Brett E. Phillips, [ ... ], Paul D. Robbins

Virtual Screening for HIV Protease Inhibitors: A Comparison of AutoDock 4 and Vina

Max W. Chang, Christian Ayeni, Sebastian Breuer, Bruce E. Torbett

High-Throughput Identification of Chemical Inhibitors of E. coli Group 2 Capsule Biogenesis as Anti-Virulence Agents

Carlos C. Goller, Patrick C. Seed

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