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Library screening

Drug Discovery for Duchenne Muscular Dystrophy via Utrophin Promoter Activation Screening

Catherine Moorwood, Olga Lozynska, Neha Suri, Andrew D. Napper, Scott L. Diamond, Tejvir S. Khurana

published 20 Oct 2011

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Pigment Epithelium-Derived Factor (PEDF) Interacts with Transportin SR2, and Active Nuclear Import Is Facilitated by a Novel Nuclear Localization Motif

Sergio Anguissola, William J. McCormack, Michelle A. Morrin, Wayne J. Higgins, Denise M. Fox, D. Margaret Worrall

published 18 Oct 2011

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A System for Performing High Throughput Assays of Synaptic Function

Chris M. Hempel, Michael Sivula, Jonathan M. Levenson, David M. Rose, Bing Li, Ana C. Sirianni, Eva Xia, Timothy A. Ryan, David J. Gerber, Jeffrey R. Cottrell

published 05 Oct 2011

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Discovery of Diverse Small Molecule Chemotypes with Cell-Based PKD1 Inhibitory Activity

Elizabeth R. Sharlow, Gabriela Mustata Wilson, David Close, Stephanie Leimgruber, Manuj Tandon, Robyn B. Reed, Tong Ying Shun, Q. Jane Wang, Peter Wipf, John S. Lazo

published 05 Oct 2011

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An Integrated PCR Colony Hybridization Approach to Screen cDNA Libraries for Full-Length Coding Sequences

Jacob Pollier, Miguel González-Guzmán, Wilson Ardiles-Diaz, Danny Geelen, Alain Goossens

published 15 Sep 2011

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Styryl-Based and Tricyclic Compounds as Potential Anti-Prion Agents

Erika Chung, Frances Prelli, Stephen Dealler, Woo Sirl Lee, Young-Tae Chang, Thomas Wisniewski

published 13 Sep 2011

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GM-CSF Production Allows the Identification of Immunoprevalent Antigens Recognized by Human CD4+ T Cells Following Smallpox Vaccination

Valeria Judkowski, Alcinette Bunying, Feng Ge, Jon R. Appel, Kingyee Law, Atima Sharma, Claudia Raja- Gabaglia, Patricia Norori, Radleigh G. Santos, Marc A. Giulianotti, Mark K. Slifka, Daniel C. Douek, Barney S. Graham, Clemencia Pinilla

published 09 Sep 2011

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Recombining Low Homology, Functionally Rich Regions of Bacterial Subtilisins by Combinatorial Fragment Exchange

D. Dafydd Jones

published 07 Sep 2011

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High-Content Chemical and RNAi Screens for Suppressors of Neurotoxicity in a Huntington's Disease Model

Joost Schulte, Katharine J. Sepp, Chaohong Wu, Pengyu Hong, J. Troy Littleton

published 31 Aug 2011

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Mannosidase 2, alpha 1 Deficiency Is Associated with Ricin Resistance in Embryonic Stem (ES) Cells

Wei Wang, Christine Hale, Dave Goulding, Stuart M. Haslam, Bérangère Tissot, Christopher Lindsay, Stephen Michell, Rick Titball, Jun Yu, Ana Luisa Toribio, Raffaella Rossi, Anne Dell, Allan Bradley, Gordon Dougan

published 23 Aug 2011

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GPR50 Interacts with TIP60 to Modulate Glucocorticoid Receptor Signalling

Jian Li, Laura E. Hand, Qing-Jun Meng, Andrew S. I. Loudon, David A. Bechtold

published 17 Aug 2011

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Rapid Probing of Biological Surfaces with a Sparse-Matrix Peptide Library

Daniel K. Yarbrough, Randal Eckert, Jian He, Elizabeth Hagerman, Fengxia Qi, Renate Lux, Ben Wu, Maxwell H. Anderson, Wenyuan Shi

published 15 Aug 2011

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Identification of Novel Immunoregulatory Molecules in Human Thymic Regulatory CD4⁺CD25⁺ T Cells by Phage Display

Georgia Porto, Ricardo J. Giordano, Luciana C. Marti, Beatriz Stolf, Renata Pasqualini, Wadih Arap, Jorge Kalil, Verônica Coelho

published 01 Aug 2011

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