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Library screening

Genetic Screening of New Genes Responsible for Cellular Adaptation to Hypoxia Using a Genome-Wide shRNA Library

Seiko Yoshino, Toshiro Hara, [ ... ], Takeharu Sakamoto

Modulators of Prostate Cancer Cell Proliferation and Viability Identified by Short-Hairpin RNA Library Screening

Kimberly Brown Dahlman, Joel S. Parker, [ ... ], Charles L. Sawyers

HIV-1 Phenotypic Reverse Transcriptase Inhibitor Drug Resistance Test Interpretation Is Not Dependent on the Subtype of the Virus Backbone

Michelle Bronze, Kim Steegen, [ ... ], on behalf of the ART-A Consortium

Identification of Novel Mt-Guab2 Inhibitor Series Active against M. tuberculosis

Veeraraghavan Usha, Judith V. Hobrath, [ ... ], Gurdyal S. Besra

Highly Parallel Translation of DNA Sequences into Small Molecules

Rebecca M. Weisinger, S. Jarrett Wrenn, Pehr B. Harbury

The Role of the Parkinson's Disease Gene PARK9 in Essential Cellular Pathways and the Manganese Homeostasis Network in Yeast

Alessandra Chesi, Austin Kilaru, [ ... ], Aaron D. Gitler

Rationalization and Design of the Complementarity Determining Region Sequences in an Antibody-Antigen Recognition Interface

Chung-Ming Yu, Hung-Pin Peng, [ ... ], An-Suei Yang

A Chemical Analog of Curcumin as an Improved Inhibitor of Amyloid Abeta Oligomerization

Robert A. Orlando, Amanda M. Gonzales, [ ... ], David L. Vander Jagt

Enabling Large-Scale Design, Synthesis and Validation of Small Molecule Protein-Protein Antagonists

David Koes, Kareem Khoury, [ ... ], Carlos J. Camacho

Discovery of Inhibitors of Leishmania β-1,2-Mannosyltransferases Using a Click-Chemistry-Derived Guanosine Monophosphate Library

Phillip van der Peet, Julie E. Ralton, Malcolm J. McConville, Spencer J. Williams

Core Site-Moiety Maps Reveal Inhibitors and Binding Mechanisms of Orthologous Proteins by Screening Compound Libraries

Kai-Cheng Hsu, Wen-Chi Cheng, [ ... ], Jinn-Moon Yang

Identification of Mammalian Protein Quality Control Factors by High-Throughput Cellular Imaging

Gianluca Pegoraro, Ty C. Voss, [ ... ], Tom Misteli

Novel Protein Kinase Signaling Systems Regulating Lifespan Identified by Small Molecule Library Screening Using Drosophila

Stephen R. Spindler, Rui Li, [ ... ], Frank Sauer

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