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Library screening

Pan-Pathway Based Interaction Profiling of FDA-Approved Nucleoside and Nucleobase Analogs with Enzymes of the Human Nucleotide Metabolism

Louise Egeblad, Martin Welin, Susanne Flodin, Susanne Gräslund, Liya Wang, Jan Balzarini, Staffan Eriksson, Pär Nordlund

published 25 May 2012

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Conserved Orb6 Phosphorylation Sites Are Essential for Polarized Cell Growth in Schizosaccharomyces pombe

Guohong Liu, Dallan Young

published 21 May 2012

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Genes Important for Catalase Activity in Enterococcus faecalis

Michael Baureder, Lars Hederstedt

published 10 May 2012

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A Genome-Wide siRNA Screen to Identify Modulators of Insulin Sensitivity and Gluconeogenesis

Ruojing Yang, Raul G. Lacson, Gino Castriota, Xiaohua D. Zhang, Yaping Liu, Wenqing Zhao, Monica Einstein, Luiz Miguel Camargo, Sajjad Qureshi, Kenny K. Wong, Bei B. Zhang, Marc Ferrer, Joel P. Berger

published 09 May 2012

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High Throughput Screening for Small Molecule Enhancers of the Interferon Signaling Pathway to Drive Next-Generation Antiviral Drug Discovery

Dhara A. Patel, Anand C. Patel, William C. Nolan, Yong Zhang, Michael J. Holtzman

published 04 May 2012

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Exploring the Dynamic Range of the Kinetic Exclusion Assay in Characterizing Antigen-Antibody Interactions

Christine Bee, Yasmina N. Abdiche, Donna M. Stone, Sierra Collier, Kevin C. Lindquist, Alanna C. Pinkerton, Jaume Pons, Arvind Rajpal

published 30 Apr 2012

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A Novel Inhibitor of Human La Protein with Anti-HBV Activity Discovered by Structure-Based Virtual Screening and In Vitro Evaluation

Jing Tang, Zhi-Min Huang, Ying-Yi Chen, Zhao-Hui Zhang, Gao-Lin Liu, Jian Zhang

published 27 Apr 2012

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Receptor Tyrosine Kinases Activate Canonical WNT/β-Catenin Signaling via MAP Kinase/LRP6 Pathway and Direct β-Catenin Phosphorylation

Pavel Krejci, Anie Aklian, Marketa Kaucka, Eva Sevcikova, Jirina Prochazkova, Jan Kukla Masek, Pavol Mikolka, Tereza Pospisilova, Tereza Spoustova, MaryAnn Weis, William A. Paznekas, Joshua H. Wolf, J. Silvio Gutkind, William R. Wilcox, Alois Kozubik, Ethylin Wang Jabs, Vitezslav Bryja, Lisa Salazar, Iva Vesela, Lukas Balek

published 27 Apr 2012

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TDP-43 Identified from a Genome Wide RNAi Screen for SOD1 Regulators

Balajee R. Somalinga, Cameron E. Day, Shuguang Wei, Michael G. Roth, Philip J. Thomas

published 26 Apr 2012

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Zebrafish Chemical Screening Reveals the Impairment of Dopaminergic Neuronal Survival by Cardiac Glycosides

Yaping Sun, Zhiqiang Dong, Hadie Khodabakhsh, Sandip Chatterjee, Su Guo

published 26 Apr 2012

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Assessment of Pseudomonas aeruginosa N⁵,N¹⁰-Methylenetetrahydrofolate Dehydrogenase - Cyclohydrolase as a Potential Antibacterial Drug Target

Thomas C. Eadsforth, Mary Gardiner, Fernando V. Maluf, Stuart McElroy, Daniel James, Julie Frearson, David Gray, William N. Hunter

published 25 Apr 2012

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IspE Inhibitors Identified by a Combination of In Silico and In Vitro High-Throughput Screening

Naomi Tidten-Luksch, Raffaella Grimaldi, Leah S. Torrie, Julie A. Frearson, William N. Hunter, Ruth Brenk

published 25 Apr 2012

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Role of H- and D- MATE-Type Transporters from Multidrug Resistant Clinical Isolates of Vibrio fluvialis in Conferring Fluoroquinolone Resistance

Priyabrata Mohanty, Arati Patel, Ashima Kushwaha Bhardwaj

published 23 Apr 2012

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