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Library screening

Functional Metagenomics Reveals Novel Pathways of Prebiotic Breakdown by Human Gut Bacteria

Davide A. Cecchini, Elisabeth Laville, [ ... ], Gabrielle Potocki-Véronèse

Targeting YAP/TAZ-TEAD protein-protein interactions using fragment-based and computational modeling approaches

Hung Yi Kristal Kaan, Adelene Y. L. Sim, [ ... ], Haiwei Song

Genome-Wide CRISPR-Cas9 Screen Identifies MicroRNAs That Regulate Myeloid Leukemia Cell Growth

Jared Wallace, Ruozhen Hu, [ ... ], Ryan M. O’Connell

Expression optimization, purification, and functional characterization of cholesterol oxidase from Chromobacterium sp. DS1

Aliakbar Fazaeli, Abolfazl Golestani, [ ... ], Mahdi Aminian

Discovery of High-Affinity Protein Binding Ligands – Backwards

Chris W. Diehnelt, Miti Shah, [ ... ], Stephen Albert Johnston

Small Molecule Inhibitors of the LEDGF Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design

Thomas S. Peat, David I. Rhodes, [ ... ], John J. Deadman

Optimized PCR Conditions and Increased shRNA Fold Representation Improve Reproducibility of Pooled shRNA Screens

Žaklina Strezoska, Abel Licon, [ ... ], Annaleen Vermeulen

Engineering T Cell Function Using Chimeric Antigen Receptors Identified Using a DNA Library Approach

Connie P. M. Duong, Jennifer A. Westwood, [ ... ], Michael H. Kershaw

Drug Discovery for Duchenne Muscular Dystrophy via Utrophin Promoter Activation Screening

Catherine Moorwood, Olga Lozynska, [ ... ], Tejvir S. Khurana

Design and Selection of a Camelid Single-Chain Antibody Yeast Two-Hybrid Library Produced De Novo for the Cap Protein of Porcine Circovirus Type 2 (PCV2)

Xiangjing Fu, Xiaolong Gao, [ ... ], Zengqi Yang

A Genetic Screen Using the PiggyBac Transposon in Haploid Cells Identifies Parp1 as a Mediator of Olaparib Toxicity

Stephen J. Pettitt, Farah L. Rehman, [ ... ], Alan Ashworth

The Metagenome-Derived Enzymes LipS and LipT Increase the Diversity of Known Lipases

Jennifer Chow, Filip Kovacic, [ ... ], Wolfgang R. Streit

Locking the 150-Cavity Open: In Silico Design and Verification of Influenza Neuraminidase Inhibitors

Nanyu Han, Yuguang Mu

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