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Library screening

Insilico targeting of virus entry facilitator NRP1 to block SARS-CoV2 entry

Nousheen Bibi, Maleeha Shah, Shahzad Khan, Muhammad Shahzad Chohan, Mohammad Amjad Kamal

published 05 Feb 2025

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Structure-guided identification of mitogen-activated protein kinase-1 inhibitors towards anticancer therapeutics

Md Nayab Sulaimani, Shazia Ahmed, Farah Anjum, Taj Mohammad, Anas Shamsi, Ravins Dohare, Md. Imtaiyaz Hassan

published 24 Jan 2025

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Pooled PPIseq: Screening the SARS-CoV-2 and human interface with a scalable multiplexed protein-protein interaction assay platform

Darach Miller, Adam Dziulko, Sasha Levy

published 17 Jan 2025

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Pharmacophore modeling and QSAR analysis of anti-HBV flavonols

Basireh Baei, Parnia Askari, Fatemeh Sana Askari, Seyed Jalal Kiani, Alireza Mohebbi

published 13 Jan 2025

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Bridging the gap in customised housing design: Integrating a graphic user interface for user collaboration

Micaela Raposo, Sara Eloy, Miguel Sales Dias

published 20 Dec 2024

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GO-CRISPR: A highly controlled workflow to discover gene essentiality in loss-of-function screens

Pirunthan Perampalam, James I. McDonald, Frederick A. Dick

published 18 Dec 2024

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Screening novel antiviral compounds to treat Clostridioides difficile infections

Brice J. Stolz, Ahmed A. Abouelkhair, Mohamed N. Seleem

published 13 Dec 2024

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Optogenetic screening of MCT1 activity implicates a cluster of non-steroidal anti-inflammatory drugs (NSAIDs) as inhibitors of lactate transport

Scott A. Wegner, Hahn Kim, José L. Avalos

published 12 Dec 2024

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Administration of novobiocin and apomorphine mitigates cholera toxin mediated cellular toxicity: Lessons from cholera toxin yeast model system

Sonali Eknath Bhalerao, Himanshu Sen, Saumya Raychaudhuri

published 05 Dec 2024

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Insilico discovery of novel Phosphodiesterase 4 (PDE4) inhibitors for the treatment of psoriasis: Insights from computer aided drug design approaches

Abdullah R. Alanzi, Mohammed S. Alsalhi, Ramzi A. Mothana, Jawaher H. Alqahtani, Moneerah J. Alqahtani

published 13 Nov 2024

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Identification of small molecule agonists of fetal hemoglobin expression for the treatment of sickle cell disease

Jian-Ping Yang, Rachel Toughiri, Anshu P. Gounder, Dan Scheibe, Matt Petrus, Sarah J. Fink, Sebastien Vallee, Jon Kenniston, Nikolaos Papaioannou, Steve Langston, Narender R. Gavva, Shane R. Horman

published 06 Nov 2024

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Phage libraries screening on P53: Yield improvement by zinc and a new parasites-integrating analysis

Sihem Ben Abid, Emna Ketata, Ines Yacoubi, Lamia Djemal, Salma Abdelmoula-Souissi, Aida Koubaa, Raja Mokdad-Gargouri, Ali Gargouri

published 03 Oct 2024

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Health professionals’ attitudes towards traditional healing for mental illness: A systematic review protocol

Alemayehu Molla Wollie, Kim Usher, Reshin Maharaj, Md Shahidul Islam

published 09 Sep 2024

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