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Library screening

The third intracellular loop of Drosophila Lilipod is required for protein function in vivo and can mediate protein-protein interactions in vitro

Merin Vellooparambil Roy, Scott J. Neal, Francesca Pignoni

published 04 Jun 2025

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Anti-cancer activity elucidation of geissolosimine as an MDM2-p53 interaction inhibitor: An in-silico study

Md. Al-Amin, Rehnuma Tanjin, Md. Rasul Karim, Jannatul Mawa Etee, Ayesha Siddika, Nafisa Akter, Md. Helal Uddin, Ratul Mahmud, Tasfia Saffat, Md. Faruk Hossen, Samira Idris Mowlee, Elmu Kabir Rafa, Sumi Akter

published 08 May 2025

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Use of allele-specific qPCR and PCR-RFLP analysis for rapid detection of the SARS-CoV-2 variants in Tunisia: A cheap flexible approach adapted for developing countries

Wajdi Ayadi, Fahmi Smaoui, Saba Gargouri, Sana Ferjani, Zaineb Hamzaoui, Awatef Taktak, Amel Chtourou, Houda Skouri-Gargouri, Azza Hadj Sassi, Mouna Ben Sassi, Sameh Trabelsi, Ali Gargouri, Ilhem Boutiba-Ben Boubaker, Héla Karray-Hakim, Raja Mokdad-Gargouri, Lamia Feki-Berrajah

published 05 May 2025

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Virtual screening and molecular dynamics simulation study of ATP-competitive inhibitors targeting mTOR protein

Mei-Yu Jin, Hao Yu, Qiong Deng, Zhu Wang, Jie-Yan Wang, Hao-Long Li, Hui Liang

published 05 May 2025

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Construction of cDNA library of Dalbergia odorifera induced by low temperature stress and screening of low temperature tolerant genes

Shaocui Li, Xia An, Fayong Li, Yining Chen, Xiaowen Li

published 01 Apr 2025

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Exploration of small molecules as inhibitors of potential BACE1 protein to treat amyloid cerebrovascular disease by employing molecular modeling and simulation approaches

Zhizhong Wang, Zhiyong Li, Ailong Lin, Qing Zhang, Yingchun Chen, Bizhou Bie, Juanjuan Feng

published 21 Mar 2025

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Combatting antibiotic resistance in Gardnerella vaginalis: A comparative in silico investigation for drug target identification

Rabbia Riaz, Kanwal Khan, Saltanat Aghayeva, Reaz Uddin

published 12 Mar 2025

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Semi-rational evolution of a recombinant DNA polymerase for modified nucleotide incorporation efficiency

Lili Zhai, Zi Wang, Fen Liu, Chongjun Xu, Jingjing Wang, Hongyan Han, Qingqing Xie, Wenwei Zhang, Yue Zheng, Alexander K. Buell, Yuliang Dong

published 14 Feb 2025

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Development of a reliable, sensitive, and convenient assay for the discovery of new eIF5A hypusination inhibitors

Oumayma Benaceur, Paula Ferreira Montenegro, Michel Kahi, Fabien Fontaine-Vive, Nathalie M. Mazure, Mohamed Mehiri, Frederic Bost, Pascal Peraldi

published 12 Feb 2025

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Insilico targeting of virus entry facilitator NRP1 to block SARS-CoV2 entry

Nousheen Bibi, Maleeha Shah, Shahzad Khan, Muhammad Shahzad Chohan, Mohammad Amjad Kamal

published 05 Feb 2025

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Structure-guided identification of mitogen-activated protein kinase-1 inhibitors towards anticancer therapeutics

Md Nayab Sulaimani, Shazia Ahmed, Farah Anjum, Taj Mohammad, Anas Shamsi, Ravins Dohare, Md. Imtaiyaz Hassan

published 24 Jan 2025

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Pooled PPIseq: Screening the SARS-CoV-2 and human interface with a scalable multiplexed protein-protein interaction assay platform

Darach Miller, Adam Dziulko, Sasha Levy

published 17 Jan 2025

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Pharmacophore modeling and QSAR analysis of anti-HBV flavonols

Basireh Baei, Parnia Askari, Fatemeh Sana Askari, Seyed Jalal Kiani, Alireza Mohebbi

published 13 Jan 2025

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