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Library screening

Xenopus: An alternative model system for identifying muco-active agents

Hyo Jung Sim, Sang-Hyun Kim, [ ... ], Tae Joo Park

A generic HTS assay for kinase screening: Validation for the isolation of an engineered malate kinase

Romain Irague, Christopher M. Topham, [ ... ], Magali Remaud-Siméon

Conservation and lineage-specific rearrangements in the GOBP/PBP gene complex of distantly related ditrysian Lepidoptera

Yuji Yasukochi, Bin Yang, [ ... ], Yukio Ishikawa

Target discovery screens using pooled shRNA libraries and next-generation sequencing: A model workflow and analytical algorithm

Christiane Schaefer, Nikhil Mallela, [ ... ], Jenny Potratz

An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells

Katharina Schrade, Jessica Tröger, [ ... ], Enno Klussmann

A pharmacological screen for compounds that rescue the developmental lethality of a Drosophila ATM mutant

Stacey A. Rimkus, David A. Wassarman

Application of a phenotypic drug discovery strategy to identify biological and chemical starting points for inhibition of TSLP production in lung epithelial cells

Adelina Orellana, Vicente García-González, [ ... ], Arsenio Nueda

Isolation and characterization of a novel metagenomic enzyme capable of degrading bacterial phytotoxin toxoflavin

Ji-Eun Choi, Cuong Mai Nguyen, [ ... ], Jae Kwang Song

Using thermal scanning assays to test protein-protein interactions of inner-ear cadherins

Deepanshu Choudhary, Anusha Kumar, Thomas J. Magliery, Marcos Sotomayor

Discovery of carbamate degrading enzymes by functional metagenomics

Lisa Ufarté, Elisabeth Laville, [ ... ], Gabrielle Potocki-Veronese

Development of a homogenous high-throughput assay for inositol hexakisphosphate kinase 1 activity

Michael Wormald, Gangling Liao, [ ... ], Huijun Wei

RNAi screen reveals a role of SPHK2 in dengue virus–mediated apoptosis in hepatic cell lines

Atthapan Morchang, Regina Ching Hua Lee, [ ... ], Thawornchai Limjindaporn

A composite docking approach for the identification and characterization of ectosteric inhibitors of cathepsin K

Simon Law, Preety Panwar, [ ... ], Dieter Brömme

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