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Library screening

Clinically relevant inflammatory breast cancer patient-derived xenograft–derived ex vivo model for evaluation of tumor-specific therapies

Bedrich L. Eckhardt, Maria Gagliardi, LaKesla Iles, Kurt Evans, Cristina Ivan, Xiuping Liu, Chang-Gong Liu, Glauco Souza, Arvind Rao, Funda Meric-Bernstam, Naoto T. Ueno, Geoffrey A. Bartholomeusz

published 16 May 2018

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Pathogen Box screening for hit identification against Mycobacterium abscessus

Jinsun Jeong, Guehye Kim, Cheol Moon, Hyun Jung Kim, Tae Ho Kim, Jichan Jang

published 26 Apr 2018

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Saccharomyces cerevisiae as a platform for assessing sphingolipid lipid kinase inhibitors

Yugesh Kharel, Sayeh Agah, Tao Huang, Anna J. Mendelson, Oluwafunmilayo T. Eletu, Peter Barkey-Bircann, James Gesualdi, Jeffrey S. Smith, Webster L. Santos, Kevin R. Lynch

published 19 Apr 2018

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Molecular engineering of the salicylate-inducible transcription factor Sal7AR for orthogonal and high gene expression in Escherichia coli

Kentaro Miyazaki

published 11 Apr 2018

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Class I HDAC inhibition is a novel pathway for regulating astrocytic apoE secretion

Erica Dresselhaus, James M. Duerr, Fabien Vincent, Emily K. Sylvain, Mercedes Beyna, Lorraine F. Lanyon, Erik LaChapelle, Martin Pettersson, Kelly R. Bales, Gayathri Ramaswamy

published 26 Mar 2018

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Comparative oncology approach to drug repurposing in osteosarcoma

Alejandro Parrales, Peter McDonald, Megan Ottomeyer, Anuradha Roy, Frank J. Shoenen, Melinda Broward, Tyce Bruns, Douglas H. Thamm, Scott J. Weir, Kathleen A. Neville, Tomoo Iwakuma, Joy M. Fulbright

published 26 Mar 2018

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PuLSE: Quality control and quantification of peptide sequences explored by phage display libraries

Steven Shave, Stefan Mann, Joanna Koszela, Alastair Kerr, Manfred Auer

published 23 Feb 2018

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Xenopus: An alternative model system for identifying muco-active agents

Hyo Jung Sim, Sang-Hyun Kim, Kyung-Jae Myung, Taejoon Kwon, Hyun-Shik Lee, Tae Joo Park

published 22 Feb 2018

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A generic HTS assay for kinase screening: Validation for the isolation of an engineered malate kinase

Romain Irague, Christopher M. Topham, Nelly Martineau, Audrey Baylac, Clément Auriol, Thomas Walther, Jean-Marie François, Isabelle André, Magali Remaud-Siméon

published 20 Feb 2018

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Conservation and lineage-specific rearrangements in the GOBP/PBP gene complex of distantly related ditrysian Lepidoptera

Yuji Yasukochi, Bin Yang, Toshiaki Fujimoto, Ken Sahara, Takashi Matsuo, Yukio Ishikawa

published 09 Feb 2018

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Target discovery screens using pooled shRNA libraries and next-generation sequencing: A model workflow and analytical algorithm

Christiane Schaefer, Nikhil Mallela, Jochen Seggewiß, Birgit Lechtape, Heymut Omran, Uta Dirksen, Eberhard Korsching, Jenny Potratz

published 31 Jan 2018

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An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells

Katharina Schrade, Jessica Tröger, Adeeb Eldahshan, Kerstin Zühlke, Kamal R. Abdul Azeez, Jonathan M. Elkins, Martin Neuenschwander, Andreas Oder, Mohamed Elkewedi, Sarah Jaksch, Karsten Andrae, Jinliang Li, Joao Fernandes, Paul Markus Müller, Stephan Grunwald, Stephen F. Marino, Tanja Vukićević, Jenny Eichhorst, Burkhard Wiesner, Marcus Weber, Michael Kapiloff, Oliver Rocks, Oliver Daumke, Thomas Wieland, Stefan Knapp, Jens Peter von Kries, Enno Klussmann

published 26 Jan 2018

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A pharmacological screen for compounds that rescue the developmental lethality of a Drosophila ATM mutant

Stacey A. Rimkus, David A. Wassarman

published 16 Jan 2018

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