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Library screening

Peak emission wavelength and fluorescence lifetime are coupled in far-red, GFP-like fluorescent proteins

Laura Canty, Santosh Hariharan, Qian Liu, Steven A. Haney, David W. Andrews

published 28 Nov 2018

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Novel high–throughput myofibroblast assays identify agonists with therapeutic potential in pulmonary fibrosis that act via EP₂ and EP₄ receptors

Patrick Sieber, Anny Schäfer, Raphael Lieberherr, François Le Goff, Manuel Stritt, Richard W. D. Welford, John Gatfield, Oliver Peter, Oliver Nayler, Urs Lüthi

published 28 Nov 2018

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Novel RNA aptamers targeting gastrointestinal cancer biomarkers CEA, CA50 and CA72-4 with superior affinity and specificity

Qing Pan, Carmen O. K. Law, Mingo M. H. Yung, K. C. Han, Yuen Lam Pon, Terrence Chi Kong Lau

published 10 Oct 2018

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Predictive classifier models built from natural products with antimalarial bioactivity using machine learning approach

Samuel Egieyeh, James Syce, Sarel F. Malan, Alan Christoffels

published 28 Sep 2018

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Silk genes and silk gene expression in the spider Tengella perfuga (Zoropsidae), including a potential cribellar spidroin (CrSp)

Sandra M. Correa-Garhwal, R. Crystal Chaw, Thomas H. Clarke III, Liliana G. Alaniz, Fanny S. Chan, Rachael E. Alfaro, Cheryl Y. Hayashi

published 20 Sep 2018

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Ex vivo drug sensitivity testing as a means for drug repurposing in esophageal adenocarcinoma

Ines Lohse, Hassan Al-Ali, Claude-Henry Volmar, Annamil D. Alvarez Trotta, Shaun P. Brothers, Anthony J. Capobianco, Claes Wahlestedt

published 13 Sep 2018

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Virtual screening using covalent docking to find activators for G245S mutant p53

Sara Ibrahim Omar, Marco Gaetano Lepre, Umberto Morbiducci, Marco Agostino Deriu, Jack A. Tuszynski

published 07 Sep 2018

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Deformable 96-well cell culture plate compatible with high-throughput screening platforms

Tsubasa S. Matsui, Hugejile Wu, Shinji Deguchi

published 06 Sep 2018

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Bridging immunogenetics and immunoproteomics: Model positional scanning library analysis for Major Histocompatibility Complex class II DQ in Tursiops truncatus

Colette T. Dooley, Tatiana Ferrer, Heidi Pagán, Gregory M. O’Corry-Crowe

published 02 Aug 2018

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Discovery of fragments that target key interactions in the signal recognition particle (SRP) as potential leads for a new class of antibiotics

Camilla Faoro, Lorna Wilkinson-White, Ann H. Kwan, Sandro F. Ataide

published 25 Jul 2018

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High content, high-throughput screening for small molecule inducers of NF-κB translocation

Samuel Njikan, Alyssa J. Manning, Yulia Ovechkina, Divya Awasthi, Tanya Parish

published 28 Jun 2018

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CRISPR/Cas-based customization of pooled CRISPR libraries

Jiyeon Kweon, Da-eun Kim, An-Hee Jang, Yongsub Kim

published 20 Jun 2018

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A CRISPR screen identifies MAPK7 as a target for combination with MEK inhibition in KRAS mutant NSCLC

Nicholas Dompe, Christiaan Klijn, Sara A. Watson, Katherine Leng, Jenna Port, Trinna Cuellar, Colin Watanabe, Benjamin Haley, Richard Neve, Marie Evangelista, David Stokoe

published 18 Jun 2018

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