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Library screening

Virtual screening using covalent docking to find activators for G245S mutant p53

Sara Ibrahim Omar, Marco Gaetano Lepre, Umberto Morbiducci, Marco Agostino Deriu, Jack A. Tuszynski

published 07 Sep 2018

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Deformable 96-well cell culture plate compatible with high-throughput screening platforms

Tsubasa S. Matsui, Hugejile Wu, Shinji Deguchi

published 06 Sep 2018

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Bridging immunogenetics and immunoproteomics: Model positional scanning library analysis for Major Histocompatibility Complex class II DQ in Tursiops truncatus

Colette T. Dooley, Tatiana Ferrer, Heidi Pagán, Gregory M. O’Corry-Crowe

published 02 Aug 2018

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Discovery of fragments that target key interactions in the signal recognition particle (SRP) as potential leads for a new class of antibiotics

Camilla Faoro, Lorna Wilkinson-White, Ann H. Kwan, Sandro F. Ataide

published 25 Jul 2018

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High content, high-throughput screening for small molecule inducers of NF-κB translocation

Samuel Njikan, Alyssa J. Manning, Yulia Ovechkina, Divya Awasthi, Tanya Parish

published 28 Jun 2018

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CRISPR/Cas-based customization of pooled CRISPR libraries

Jiyeon Kweon, Da-eun Kim, An-Hee Jang, Yongsub Kim

published 20 Jun 2018

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A CRISPR screen identifies MAPK7 as a target for combination with MEK inhibition in KRAS mutant NSCLC

Nicholas Dompe, Christiaan Klijn, Sara A. Watson, Katherine Leng, Jenna Port, Trinna Cuellar, Colin Watanabe, Benjamin Haley, Richard Neve, Marie Evangelista, David Stokoe

published 18 Jun 2018

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Drug discovery with an RBM20 dependent titin splice reporter identifies cardenolides as lead structures to improve cardiac filling

Martin Liss, Michael H. Radke, Jamina Eckhard, Martin Neuenschwander, Vita Dauksaite, Jens-Peter von Kries, Michael Gotthardt

published 11 Jun 2018

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Dissection of the antimicrobial and hemolytic activity of Cap18: Generation of Cap18 derivatives with enhanced specificity

Anna Ebbensgaard, Hanne Mordhorst, Michael Toft Overgaard, Frank Møller Aarestrup, Egon Bech Hansen

published 31 May 2018

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Design of a glutamine substrate tag enabling protein labelling mediated by Bacillus subtilis transglutaminase

Samuel K. Oteng-Pabi, Christopher M. Clouthier, Jeffrey W. Keillor

published 30 May 2018

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RNAi screening of subtracted transcriptomes reveals tumor suppression by taurine-activated GABA_A receptors involved in volume regulation

Camiel L. C. Wielders, Pim van Nierop, Tinke L. Vormer, Floris Foijer, Joanne Verheij, Johannes C. Lodder, Jesper B. Andersen, Huibert D. Mansvelder, Hein te Riele

published 22 May 2018

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Rosmarinic acid is a novel inhibitor for Hepatitis B virus replication targeting viral epsilon RNA-polymerase interaction

Yuta Tsukamoto, Sotaro Ikeda, Koji Uwai, Riho Taguchi, Kazuaki Chayama, Takemasa Sakaguchi, Ryo Narita, Wan-Ling Yao, Fumihiko Takeuchi, Yukie Otakaki, Koichi Watashi, Takaji Wakita, Hiroki Kato, Takashi Fujita

published 21 May 2018

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Construction and characterization of a bacterial artificial chromosome library for Gossypium mustelinum

Yuling Liu, Baohong Zhang, Xinpeng Wen, Shulin Zhang, Yangyang Wei, Quanwei Lu, Zhen Liu, Kunbo Wang, Fang Liu, Renhai Peng

published 17 May 2018

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