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Library screening

Peak emission wavelength and fluorescence lifetime are coupled in far-red, GFP-like fluorescent proteins

Laura Canty, Santosh Hariharan, [ ... ], David W. Andrews

Novel high–throughput myofibroblast assays identify agonists with therapeutic potential in pulmonary fibrosis that act via EP₂ and EP₄ receptors

Patrick Sieber, Anny Schäfer, [ ... ], Urs Lüthi

Novel RNA aptamers targeting gastrointestinal cancer biomarkers CEA, CA50 and CA72-4 with superior affinity and specificity

Qing Pan, Carmen O. K. Law, [ ... ], Terrence Chi Kong Lau

Predictive classifier models built from natural products with antimalarial bioactivity using machine learning approach

Samuel Egieyeh, James Syce, Sarel F. Malan, Alan Christoffels

Silk genes and silk gene expression in the spider Tengella perfuga (Zoropsidae), including a potential cribellar spidroin (CrSp)

Sandra M. Correa-Garhwal, R. Crystal Chaw, [ ... ], Cheryl Y. Hayashi

Ex vivo drug sensitivity testing as a means for drug repurposing in esophageal adenocarcinoma

Ines Lohse, Hassan Al-Ali, [ ... ], Claes Wahlestedt

Virtual screening using covalent docking to find activators for G245S mutant p53

Sara Ibrahim Omar, Marco Gaetano Lepre, [ ... ], Jack A. Tuszynski

Deformable 96-well cell culture plate compatible with high-throughput screening platforms

Tsubasa S. Matsui, Hugejile Wu, Shinji Deguchi

Bridging immunogenetics and immunoproteomics: Model positional scanning library analysis for Major Histocompatibility Complex class II DQ in Tursiops truncatus

Colette T. Dooley, Tatiana Ferrer, Heidi Pagán, Gregory M. O’Corry-Crowe

Discovery of fragments that target key interactions in the signal recognition particle (SRP) as potential leads for a new class of antibiotics

Camilla Faoro, Lorna Wilkinson-White, Ann H. Kwan, Sandro F. Ataide

High content, high-throughput screening for small molecule inducers of NF-κB translocation

Samuel Njikan, Alyssa J. Manning, [ ... ], Tanya Parish

CRISPR/Cas-based customization of pooled CRISPR libraries

Jiyeon Kweon, Da-eun Kim, An-Hee Jang, Yongsub Kim

A CRISPR screen identifies MAPK7 as a target for combination with MEK inhibition in KRAS mutant NSCLC

Nicholas Dompe, Christiaan Klijn, [ ... ], David Stokoe

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