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Library screening

Deformable 96-well cell culture plate compatible with high-throughput screening platforms

Tsubasa S. Matsui, Hugejile Wu, Shinji Deguchi

Bridging immunogenetics and immunoproteomics: Model positional scanning library analysis for Major Histocompatibility Complex class II DQ in Tursiops truncatus

Colette T. Dooley, Tatiana Ferrer, Heidi Pagán, Gregory M. O’Corry-Crowe

Discovery of fragments that target key interactions in the signal recognition particle (SRP) as potential leads for a new class of antibiotics

Camilla Faoro, Lorna Wilkinson-White, Ann H. Kwan, Sandro F. Ataide

High content, high-throughput screening for small molecule inducers of NF-κB translocation

Samuel Njikan, Alyssa J. Manning, [ ... ], Tanya Parish

CRISPR/Cas-based customization of pooled CRISPR libraries

Jiyeon Kweon, Da-eun Kim, An-Hee Jang, Yongsub Kim

A CRISPR screen identifies MAPK7 as a target for combination with MEK inhibition in KRAS mutant NSCLC

Nicholas Dompe, Christiaan Klijn, [ ... ], David Stokoe

Drug discovery with an RBM20 dependent titin splice reporter identifies cardenolides as lead structures to improve cardiac filling

Martin Liss, Michael H. Radke, [ ... ], Michael Gotthardt

Dissection of the antimicrobial and hemolytic activity of Cap18: Generation of Cap18 derivatives with enhanced specificity

Anna Ebbensgaard, Hanne Mordhorst, [ ... ], Egon Bech Hansen

Design of a glutamine substrate tag enabling protein labelling mediated by Bacillus subtilis transglutaminase

Samuel K. Oteng-Pabi, Christopher M. Clouthier, Jeffrey W. Keillor

RNAi screening of subtracted transcriptomes reveals tumor suppression by taurine-activated GABA_A receptors involved in volume regulation

Camiel L. C. Wielders, Pim van Nierop, [ ... ], Hein te Riele

Rosmarinic acid is a novel inhibitor for Hepatitis B virus replication targeting viral epsilon RNA-polymerase interaction

Yuta Tsukamoto, Sotaro Ikeda, [ ... ], Takashi Fujita

Construction and characterization of a bacterial artificial chromosome library for Gossypium mustelinum

Yuling Liu, Baohong Zhang, [ ... ], Renhai Peng

Clinically relevant inflammatory breast cancer patient-derived xenograft–derived ex vivo model for evaluation of tumor-specific therapies

Bedrich L. Eckhardt, Maria Gagliardi, [ ... ], Geoffrey A. Bartholomeusz

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