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Library screening

Heme Mediates Cytotoxicity from Artemisinin and Serves as a General Anti-Proliferation Target

Shiming Zhang, Glenn S. Gerhard

Generation and Characterization of Fmr1 Knockout Zebrafish

Marjo J. den Broeder, Herma van der Linde, [ ... ], René F. Ketting

A Novel High-Throughput 3D Screening System for EMT Inhibitors: A Pilot Screening Discovered the EMT Inhibitory Activity of CDK2 Inhibitor SU9516

Kazuya Arai, Takanori Eguchi, [ ... ], Manabu Itoh

Water Oxidation by a Cytochrome P450: Mechanism and Function of the Reaction

Brinda Prasad, Derrick J. Mah, Andrew R. Lewis, Erika Plettner

Formalization, Annotation and Analysis of Diverse Drug and Probe Screening Assay Datasets Using the BioAssay Ontology (BAO)

Uma D. Vempati, Magdalena J. Przydzial, [ ... ], Stephan C. Schürer

High-Throughput Screening for Novel Inhibitors of Neisseria gonorrhoeae Penicillin-Binding Protein 2

Alena Fedarovich, Kevin A. Djordjevic, [ ... ], Christopher Davies

Engineering an Anti-Transferrin Receptor ScFv for pH-Sensitive Binding Leads to Increased Intracellular Accumulation

Benjamin J. Tillotson, Loukas I. Goulatis, [ ... ], Eric V. Shusta

Discovery of Novel Hepatitis C Virus NS5B Polymerase Inhibitors by Combining Random Forest, Multiple e-Pharmacophore Modeling and Docking

Yu Wei, Jinlong Li, [ ... ], Jianping Lin

Discovery of T Cell Antigens by High-Throughput Screening of Synthetic Minigene Libraries

Brian D. Hondowicz, Katharine V. Schwedhelm, [ ... ], Brad Stone

An Ultra High-Throughput, Whole-Animal Screen for Small Molecule Modulators of a Specific Genetic Pathway in Caenorhabditis elegans

Chi K. Leung, Ying Wang, [ ... ], Keith P. Choe

Implementation of a High-Throughput Screen for Identifying Small Molecules to Activate the Keap1-Nrf2-ARE Pathway

Kai Connie Wu, Peter R. McDonald, [ ... ], Curtis D. Klaassen

Screening for Novel LRRK2 Inhibitors Using a High-Throughput TR-FRET Cellular Assay for LRRK2 Ser935 Phosphorylation

Spencer B. Hermanson, Coby B. Carlson, [ ... ], Kun Bi

Identification of Small-Molecule Inhibitors of the HuR/RNA Interaction Using a Fluorescence Polarization Screening Assay Followed by NMR Validation

Zhonghua Wang, Akash Bhattacharya, Dmitri N. Ivanov

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