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Library screening

Comparative analysis of mutational robustness of the intrinsically disordered viral protein VPg and of its interactor eIF4E

Jocelyne Walter, Justine Charon, Yihua Hu, Joy Lachat, Thomas Leger, Guillaume Lafforgue, Amandine Barra, Thierry Michon

published 14 Feb 2019

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Expression optimization, purification, and functional characterization of cholesterol oxidase from Chromobacterium sp. DS1

Aliakbar Fazaeli, Abolfazl Golestani, Mostafa Lakzaei, Samaneh Sadat Rasi Varaei, Mahdi Aminian

published 13 Feb 2019

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Functional screening for triclosan resistance in a wastewater metagenome and isolates of Escherichia coli and Enterococcus spp. from a large Canadian healthcare region

Andrew Cameron, Ruth Barbieri, Ron Read, Deirdre Church, Emelia H. Adator, Rahat Zaheer, Tim A. McAllister

published 24 Jan 2019

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A high-throughput whole cell screen to identify inhibitors of Mycobacterium tuberculosis

Juliane Ollinger, Anuradha Kumar, David M. Roberts, Mai A. Bailey, Allen Casey, Tanya Parish

published 16 Jan 2019

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Holistic engineering of Cal-A lipase chain-length selectivity identifies triglyceride binding hot-spot

Daniela Quaglia, Lorea Alejaldre, Sara Ouadhi, Olivier Rousseau, Joelle N. Pelletier

published 14 Jan 2019

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Designing antibody against highly conserved region of dengue envelope protein by in silico screening of scFv mutant library

Abhishek Singh Rathore, Animesh Sarker, Rinkoo Devi Gupta

published 10 Jan 2019

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A high-throughput screen to identify novel small molecule inhibitors of the Werner Syndrome Helicase-Nuclease (WRN)

Joshua A. Sommers, Tomasz Kulikowicz, Deborah L. Croteau, Thomas Dexheimer, Dorjbal Dorjsuren, Ajit Jadhav, David J. Maloney, Anton Simeonov, Vilhelm A. Bohr, Robert M. Brosh Jr.

published 09 Jan 2019

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Identification of transthyretin as a novel interacting partner for the δ subunit of GABA_A receptors

Li Zhou, Xin Tang, Xinyi Li, Yuting Bai, Joel N. Buxbaum, Gong Chen

published 07 Jan 2019

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A high-throughput, whole cell assay to identify compounds active against carbapenem-resistant Klebsiella pneumoniae

Julie Liao, George Xu, Emily E. Mevers, Jon Clardy, Paula I. Watnick

published 21 Dec 2018

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A user-friendly platform for yeast two-hybrid library screening using next generation sequencing

Marie-Laure Erffelinck, Bianca Ribeiro, Maria Perassolo, Laurens Pauwels, Jacob Pollier, Veronique Storme, Alain Goossens

published 21 Dec 2018

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Screen for modulators of atonal homolog 1 gene expression using notch pathway-relevant gene transcription based cellular assays

Xin Zeng, Robert Kirkpatrick, Glenn Hofmann, Didier Grillot, Valerie Linhart, Fabrice Viviani, Joseph Marino Jr, Joseph Boyer, Taylor L. Graham, Quinn Lu, Zining Wu, Andrew Benowitz, Rick Cousins

published 12 Dec 2018

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Peak emission wavelength and fluorescence lifetime are coupled in far-red, GFP-like fluorescent proteins

Laura Canty, Santosh Hariharan, Qian Liu, Steven A. Haney, David W. Andrews

published 28 Nov 2018

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Novel high–throughput myofibroblast assays identify agonists with therapeutic potential in pulmonary fibrosis that act via EP₂ and EP₄ receptors

Patrick Sieber, Anny Schäfer, Raphael Lieberherr, François Le Goff, Manuel Stritt, Richard W. D. Welford, John Gatfield, Oliver Peter, Oliver Nayler, Urs Lüthi

published 28 Nov 2018

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