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Library screening

Anticancer compound XL765 as PI3K/mTOR dual inhibitor: A structural insight into the inhibitory mechanism using computational approaches

Mohd Rehan

published 27 Jun 2019

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Ligand-guided homology modeling drives identification of novel histamine H3 receptor ligands

David Schaller, Stefanie Hagenow, Holger Stark, Gerhard Wolber

published 25 Jun 2019

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Development and optimization of a high-throughput screening method utilizing Ancylostoma ceylanicum egg hatching to identify novel anthelmintics

Laura Abriola, Denton Hoyer, Conor R. Caffrey, David L. Williams, Timothy P. Yoshino, Jon J. Vermeire

published 03 Jun 2019

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Identification of inhibitors of an unconventional Trypanosoma brucei kinetochore kinase

Leah S. Torrie, Fabio Zuccotto, David A. Robinson, David W. Gray, Ian H. Gilbert, Manu De Rycker

published 31 May 2019

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Cbl interacts with multiple E2s in vitro and in cells

Mariya S. Liyasova, Ke Ma, Donna Voeller, Philip E. Ryan, Jinqiu Chen, Rachel E. Klevit, Stanley Lipkowitz

published 23 May 2019

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The effect of trial repetition and problem size on the consistency of decision making

Vladimír Bureš, Daniela Ponce, Pavel Čech, Karel Mls

published 06 May 2019

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Dopamine receptor antagonists as potential therapeutic agents for ADPKD

Parama Paul, Sreekumar Ramachandran, Sheng Xia, Jay R. Unruh, Juliana Conkright-Fincham, Rong Li

published 06 May 2019

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High content analysis enables high-throughput nematicide discovery screening for measurement of viability and movement behavior in response to natural product samples

Jennifer M. Petitte, Mary H. Lewis, Tucker K. Witsil, Xiang Huang, John W. Rice

published 23 Apr 2019

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Potent inhibitors of equine steroid isomerase EcaGST A3-3

Helena Lindström, Aslam M. A. Mazari, Yaman Musdal, Bengt Mannervik

published 21 Mar 2019

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ERBB2-modulated ATG4B and autophagic cell death in human ARPE19 during oxidative stress

Shwu-Jiuan Sheu, Jiunn-Liang Chen, Youn-Shen Bee, Shi-Han Lin, Chih-Wen Shu

published 14 Mar 2019

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Utilisation of the Prestwick Chemical Library to identify drugs that inhibit the growth of mycobacteria

Panchali Kanvatirth, Rose E. Jeeves, Joanna Bacon, Gurdyal S. Besra, Luke J. Alderwick

published 12 Mar 2019

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Gonadotropin regulation of ankyrin-repeat and SOCS-box protein 9 (ASB9) in ovarian follicles and identification of binding partners

Gabriel Benoit, Aly Warma, Jacques G. Lussier, Kalidou Ndiaye

published 27 Feb 2019

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Screening for inhibitor of episomal DNA identified dicumarol as a hepatitis B virus inhibitor

Fumihiko Takeuchi, Sotaro Ikeda, Yuta Tsukamoto, Yoshikazu Iwasawa, Chen Qihao, Yukie Otakaki, Ouda Ryota, Wan-Ling Yao, Ryo Narita, Hijikata Makoto, Koichi Watashi, Takaji Wakita, Koh Takeuchi, Kazuaki Chayama, Amane Kogure, Hiroki Kato, Takashi Fujita

published 19 Feb 2019

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