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Leukemia

Single-Cell STAT5 Signal Transduction Profiling in Normal and Leukemic Stem and Progenitor Cell Populations Reveals Highly Distinct Cytokine Responses

Lina Han, Albertus T. J. Wierenga, Marjan Rozenveld-Geugien, Kim van de Lande, Edo Vellenga, Jan Jacob Schuringa

published 24 Nov 2009

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High Mitochondrial DNA Stability in B-Cell Chronic Lymphocytic Leukemia

María Cerezo, Hans-Jürgen Bandelt, Idoia Martín-Guerrero, Maite Ardanaz, Ana Vega, Ángel Carracedo, África García-Orad, Antonio Salas

published 18 Nov 2009

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Acadesine Kills Chronic Myelogenous Leukemia (CML) Cells through PKC-Dependent Induction of Autophagic Cell Death

Guillaume Robert, Issam Ben Sahra, Alexandre Puissant, Pascal Colosetti, Nathalie Belhacene, Pierre Gounon, Paul Hofman, Fréderic Bost, Jill-Patrice Cassuto, Patrick Auberger

published 18 Nov 2009

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MicroRNA Patterns Associated with Clinical Prognostic Parameters and CNS Relapse Prediction in Pediatric Acute Leukemia

Hua Zhang, Xue-Qun Luo, Peng Zhang, Li-Bin Huang, Yu-Sheng Zheng, Jun Wu, Hui Zhou, Liang-Hu Qu, Ling Xu, Yue-Qin Chen

published 13 Nov 2009

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Oncogenic RAS Enables DNA Damage- and p53-Dependent Differentiation of Acute Myeloid Leukemia Cells in Response to Chemotherapy

Mona Meyer, Daniela Rübsamen, Robert Slany, Thomas Illmer, Kathleen Stabla, Petra Roth, Thorsten Stiewe, Martin Eilers, Andreas Neubauer

published 05 Nov 2009

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Reciprocal t(9;22) ABL/BCR Fusion Proteins: Leukemogenic Potential and Effects on B Cell Commitment

Xiaomin Zheng, Claudia Oancea, Reinhard Henschler, Malcolm A. S. Moore, Martin Ruthardt

published 30 Oct 2009

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Crystal Structure of the PIM2 Kinase in Complex with an Organoruthenium Inhibitor

Alex N. Bullock, Santina Russo, Ann Amos, Nicholas Pagano, Howard Bregman, Judit É. Debreczeni, Wen Hwa Lee, Frank von Delft, Eric Meggers, Stefan Knapp

published 20 Oct 2009

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IL-3 and Oncogenic Abl Regulate the Myeloblast Transcriptome by Altering mRNA Stability

Jason Ernst, Louis Ghanem, Ziv Bar-Joseph, Michael McNamara, Jason Brown, Richard A. Steinman

published 15 Oct 2009

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A BCR-ABL Mutant Lacking Direct Binding Sites for the GRB2, CBL and CRKL Adapter Proteins Fails to Induce Leukemia in Mice

Kara J. Johnson, Ian J. Griswold, Thomas O'Hare, Amie S. Corbin, Marc Loriaux, Michael W. Deininger, Brian J. Druker

published 13 Oct 2009

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Investigating the Targets of MIR-15a and MIR-16-1 in Patients with Chronic Lymphocytic Leukemia (CLL)

Katy Hanlon, Claudius E. Rudin, Lorna W. Harries

published 25 Sep 2009

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Earlier Onset of δ-Retrovirus-Induced Leukemia after Splenectomy

Arnaud Florins, Michal Reichert, Becca Asquith, Amel-Baya Bouzar, Geneviève Jean, Carole François, Agnieszka Jasik, Arsène Burny, Richard Kettmann, Luc Willems

published 14 Sep 2009

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Genome-Wide Analysis of Small RNA and Novel MicroRNA Discovery in Human Acute Lymphoblastic Leukemia Based on Extensive Sequencing Approach

Hua Zhang, Jian-Hua Yang, Yu-Sheng Zheng, Peng Zhang, Xiao Chen, Jun Wu, Ling Xu, Xue-Qun Luo, Zhi-Yong Ke, Hui Zhou, Liang-Hu Qu, Yue-Qin Chen

published 02 Sep 2009

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Regulation of PERK Signaling and Leukemic Cell Survival by a Novel Cytosolic Isoform of the UPR Regulator GRP78/BiP

Min Ni, Hui Zhou, Shiuan Wey, Peter Baumeister, Amy S. Lee

published 31 Aug 2009

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