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Leukemia

Securinine, a Myeloid Differentiation Agent with Therapeutic Potential for AML

Kalpana Gupta, Amitabha Chakrabarti, Sonia Rana, Ritu Ramdeo, Bryan L. Roth, Munna L. Agarwal, William Tse, Mukesh K. Agarwal, David N. Wald

published 24 Jun 2011

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Therapeutic Potential and Challenges of Targeting Receptor Tyrosine Kinase ROR1 with Monoclonal Antibodies in B-Cell Malignancies

Jiahui Yang, Sivasubramanian Baskar, Ka Yin Kwong, Michael G. Kennedy, Adrian Wiestner, Christoph Rader

published 15 Jun 2011

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Vorinostat Induces Reactive Oxygen Species and DNA Damage in Acute Myeloid Leukemia Cells

Luca A. Petruccelli, Daphné Dupéré-Richer, Filippa Pettersson, Hélène Retrouvey, Sophia Skoulikas, Wilson H. Miller Jr.

published 10 Jun 2011

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Genomic Imbalances Are Confined to Non-Proliferating Cells in Paediatric Patients with Acute Myeloid Leukaemia and a Normal or Incomplete Karyotype

Erica Ballabio, Regina Regan, Elisa Garimberti, Jochen Harbott, Jutta Bradtke, Andrea Teigler-Schlegel, Andrea Biondi, Giovanni Cazzaniga, Giovanni Giudici, James S. Wainscoat, Jacqueline Boultwood, Joanna M. Bridger, Samantha J. L. Knight, Sabrina Tosi

published 09 Jun 2011

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Aberrant Expression of Functional BAFF-System Receptors by Malignant B-Cell Precursors Impacts Leukemia Cell Survival

Sara Maia, Marc Pelletier, Jixin Ding, Yen-Ming Hsu, Stephen E. Sallan, Sambasiva P. Rao, Lee M. Nadler, Angelo A. Cardoso

published 08 Jun 2011

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Deactivation of Signal Transducer and Activator of Transcription 3 Reverses Chemotherapeutics Resistance of Leukemia Cells via Down-Regulating P-gp

Xulong Zhang, Weihua Xiao, Lihua Wang, Zhigang Tian, Jian Zhang

published 06 Jun 2011

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PRL-3, a Metastasis Associated Tyrosine Phosphatase, Is Involved in FLT3-ITD Signaling and Implicated in Anti-AML Therapy

Jianbiao Zhou, Chonglei Bi, Wee-Joo Chng, Lip-Lee Cheong, Shaw-Cheng Liu, Sylvia Mahara, Kian-Ghee Tay, Qi Zeng, Jie Li, Ke Guo, Cheng Peow Bobby Tan, Hanry Yu, Daniel H. Albert, Chien-Shing Chen

published 12 May 2011

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Do Stress Responses Promote Leukemia Progression? An Animal Study Suggesting a Role for Epinephrine and Prostaglandin-E₂ through Reduced NK Activity

Shelly Inbar, Elad Neeman, Roi Avraham, Marganit Benish, Ella Rosenne, Shamgar Ben-Eliyahu

published 29 Apr 2011

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Survey of Activated FLT3 Signaling in Leukemia

Ting-lei Gu, Julie Nardone, Yi Wang, Marc Loriaux, Judit Villén, Sean Beausoleil, Meghan Tucker, Jon Kornhauser, Jianmin Ren, Joan MacNeill, Steven P. Gygi, Brian J. Druker, Michael C. Heinrich, John Rush, Roberto D. Polakiewicz

published 28 Apr 2011

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Epigenetic Inactivation of the miR-124-1 in Haematological Malignancies

Kwan Yeung Wong, Chi Chiu So, Florence Loong, Lap Ping Chung, William Wai Lung Lam, Raymond Liang, George Kam Hop Li, Dong-Yan Jin, Chor Sang Chim

published 22 Apr 2011

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SALL4, a Stem Cell Factor, Affects the Side Population by Regulation of the ATP-Binding Cassette Drug Transport Genes

Ha-Won Jeong, Wei Cui, Youyang Yang, Jiayun Lu, Jie He, Ailing Li, David Song, Ye Guo, Bee H. Liu, Li Chai

published 19 Apr 2011

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Imatinib Treatment Induces CD5+ B Lymphocytes and IgM Natural Antibodies with Anti-Leukemic Reactivity in Patients with Chronic Myelogenous Leukemia

Silvia Catellani, Ivana Pierri, Marco Gobbi, Alessandro Poggi, Maria Raffaella Zocchi

published 18 Apr 2011

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Low CD4/CD8 T-Cell Ratio Associated with Inflammatory Arthropathy in Human T-Cell Leukemia Virus Type I Tax Transgenic Mice

Takeo Ohsugi, Toshio Kumasaka

published 01 Apr 2011

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