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Leukemia

Synergistic Interactions between HDAC and Sirtuin Inhibitors in Human Leukemia Cells

Michele Cea, Debora Soncini, [ ... ], Alessio Nencioni

IRF4 Is a Suppressor of c-Myc Induced B Cell Leukemia

Simanta Pathak, Shibin Ma, [ ... ], Runqing Lu

Separase Loss of Function Cooperates with the Loss of p53 in the Initiation and Progression of T- and B-Cell Lymphoma, Leukemia and Aneuploidy in Mice

Malini Mukherjee, Gouqing Ge, [ ... ], Debananda Pati

Effects of Stem Cell Factor on Hypoxia-Inducible Factor 1 Alpha Accumulation in Human Acute Myeloid Leukaemia and LAD2 Mast Cells

Bernhard F. Gibbs, Inna M. Yasinska, Abraham E. Oniku, Vadim V. Sumbayev

Sulindac Sulfide Reverses Aberrant Self-Renewal of Progenitor Cells Induced by the AML-Associated Fusion Proteins PML/RARα and PLZF/RARα

Gunnar Steinert, Claudia Oancea, [ ... ], Elena Puccetti

Exploiting Mitochondrial Dysfunction for Effective Elimination of Imatinib-Resistant Leukemic Cells

Jérome Kluza, Manel Jendoubi, [ ... ], Philippe Marchetti

Securinine, a Myeloid Differentiation Agent with Therapeutic Potential for AML

Kalpana Gupta, Amitabha Chakrabarti, [ ... ], David N. Wald

Therapeutic Potential and Challenges of Targeting Receptor Tyrosine Kinase ROR1 with Monoclonal Antibodies in B-Cell Malignancies

Jiahui Yang, Sivasubramanian Baskar, [ ... ], Christoph Rader

Vorinostat Induces Reactive Oxygen Species and DNA Damage in Acute Myeloid Leukemia Cells

Luca A. Petruccelli, Daphné Dupéré-Richer, [ ... ], Wilson H. Miller Jr.

Genomic Imbalances Are Confined to Non-Proliferating Cells in Paediatric Patients with Acute Myeloid Leukaemia and a Normal or Incomplete Karyotype

Erica Ballabio, Regina Regan, [ ... ], Sabrina Tosi

Aberrant Expression of Functional BAFF-System Receptors by Malignant B-Cell Precursors Impacts Leukemia Cell Survival

Sara Maia, Marc Pelletier, [ ... ], Angelo A. Cardoso

Deactivation of Signal Transducer and Activator of Transcription 3 Reverses Chemotherapeutics Resistance of Leukemia Cells via Down-Regulating P-gp

Xulong Zhang, Weihua Xiao, [ ... ], Jian Zhang

PRL-3, a Metastasis Associated Tyrosine Phosphatase, Is Involved in FLT3-ITD Signaling and Implicated in Anti-AML Therapy

Jianbiao Zhou, Chonglei Bi, [ ... ], Chien-Shing Chen

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