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Leukemia

Hyperforin Inhibits Akt1 Kinase Activity and Promotes Caspase-Mediated Apoptosis Involving Bad and Noxa Activation in Human Myeloid Tumor Cells

Faten Merhi, Ruoping Tang, Marion Piedfer, Julie Mathieu, Isabelle Bombarda, Murhaf Zaher, Jean-Pierre Kolb, Christian Billard, Brigitte Bauvois

published 06 Oct 2011

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3′UTR-Mediated Gene Silencing of the Mixed Lineage Leukemia (MLL) Gene

Maria Gomez-Benito, Fabricio Loayza-Puch, Joachim Oude Vrielink, Maria D. Odero, Reuven Agami

published 05 Oct 2011

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Leptin Reverts Pro-Apoptotic and Antiproliferative Effects of α-Linolenic Acids in BCR-ABL Positive Leukemic Cells: Involvement of PI3K Pathway

Aurore Beaulieu, Géraldine Poncin, Zakia Belaid-Choucair, Chantal Humblet, Gordana Bogdanovic, Georges Lognay, Jacques Boniver, Marie-Paule Defresne

published 03 Oct 2011

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Simultaneous Inhibition of mTOR-Containing Complex 1 (mTORC1) and MNK Induces Apoptosis of Cutaneous T-Cell Lymphoma (CTCL) Cells

Michal Marzec, Xiaobin Liu, Maria Wysocka, Alain H. Rook, Niels Odum, Mariusz A. Wasik

published 16 Sep 2011

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Notch3 Is Dispensable for Thymocyte β-Selection and Notch1-Induced T Cell Leukemogenesis

Sara Suliman, Joanne Tan, Keli Xu, Philaretos C. Kousis, Paul E. Kowalski, Greg Chang, Sean E. Egan, Cynthia Guidos

published 13 Sep 2011

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Targeted Drug Delivery by Gemtuzumab Ozogamicin: Mechanism-Based Mathematical Model for Treatment Strategy Improvement and Therapy Individualization

Eva Jager, Vincent H. J. van der Velden, Jeroen G. te Marvelde, Roland B. Walter, Zvia Agur, Vladimir Vainstein

published 07 Sep 2011

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Identification of Single- and Multiple-Class Specific Signature Genes from Gene Expression Profiles by Group Marker Index

Yu-Shuen Tsai, Kripamoy Aguan, Nikhil R. Pal, I-Fang Chung

published 01 Sep 2011

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Relevance of Stereotyped B-Cell Receptors in the Context of the Molecular, Cytogenetic and Clinical Features of Chronic Lymphocytic Leukemia

Francesco Maura, Giovanna Cutrona, Sonia Fabris, Monica Colombo, Giacomo Tuana, Luca Agnelli, Serena Matis, Marta Lionetti, Massimo Gentile, Anna Grazia Recchia, Francesco Di Raimondo, Caterina Musolino, Fiorella Ilariucci, Nicola Di Renzo, Emanuela Pesce, Stefano Molica, Massimo Federico, Agostino Cortelezzi, Fortunato Morabito, Manlio Ferrarini, Antonino Neri

published 29 Aug 2011

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Genetic Variants of Human Granzyme B Predict Transplant Outcomes after HLA Matched Unrelated Bone Marrow Transplantation for Myeloid Malignancies

Luis J. Espinoza, Akiyoshi Takami, Katsuya Nakata, Kayoko Yamada, Makoto Onizuka, Takakazu Kawase, Hiroshi Sao, Hideki Akiyama, Koichi Miyamura, Shinichiro Okamoto, Masami Inoue, Takahiro Fukuda, Yasuo Morishima, Yoshihisa Kodera, Shinji Nakao, for the Japan Marrow Donor Program

published 23 Aug 2011

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Icaritin Shows Potent Anti-Leukemia Activity on Chronic Myeloid Leukemia In Vitro and In Vivo by Regulating MAPK/ERK/JNK and JAK2/STAT3 /AKT Signalings

Jian feng Zhu, Zi jian Li, Guang sen Zhang, Kun Meng, Wen yong Kuang, Jin Li, Xin fu Zhou, Rui juan Li, Hong ling Peng, Chong wen Dai, Jian Kai Shen, Fan jie Gong, Yun xiao Xu, Su fang Liu

published 22 Aug 2011

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Hepcidin Levels and Their Determinants in Different Types of Myelodysplastic Syndromes

Valeria Santini, Domenico Girelli, Alessandro Sanna, Nicola Martinelli, Lorena Duca, Natascia Campostrini, Agostino Cortelezzi, Michela Corbella, Alberto Bosi, Gianluigi Reda, Oliviero Olivieri, Maria Domenica Cappellini

published 19 Aug 2011

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Differential Bone Marrow Homing Capacity of VLA-4 and CD38 High Expressing Chronic Lymphocytic Leukemia Cells

Gabriele Brachtl, Karine Sahakyan, Ursula Denk, Tamara Girbl, Beate Alinger, Sebastian W. Hofbauer, Daniel Neureiter, Josefina Piñón Hofbauer, Alexander Egle, Richard Greil, Tanja Nicole Hartmann

published 18 Aug 2011

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Targeting of T/Tn Antigens with a Plant Lectin to Kill Human Leukemia Cells by Photochemotherapy

Guillaume Poiroux, Marguerite Pitié, Raphaël Culerrier, Elodie Lafont, Bruno Ségui, Els J. M. Van Damme, Willy J. Peumans, Jean Bernadou, Thierry Levade, Pierre Rougé, Annick Barre, Hervé Benoist

published 17 Aug 2011

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