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Leukemia

Evolution of Resistance to Aurora Kinase B Inhibitors in Leukaemia Cells

Timothy W. Failes, Gorjana Mitic, Heba Abdel-Halim, Sela T. Po'uha, Marjorie Liu, David E. Hibbs, Maria Kavallaris

published 16 Feb 2012

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Optical Imaging of Disseminated Leukemia Models in Mice with Near-Infrared Probe Conjugated to a Monoclonal Antibody

Sabrina Pesnel, Arnaud Pillon, Laurent Créancier, Stéphanie Lerondel, Alain Le Pape, Christian Recher, Cécile Demur, Nicolas Guilbaud, Anna Kruczynski

published 27 Jan 2012

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The Increased Expression of Integrin α6 (ITGA6) Enhances Drug Resistance in EVI1^high Leukemia

Norio Yamakawa, Kazuko Kaneda, Yusuke Saito, Emi Ichihara, Kazuhiro Morishita

published 25 Jan 2012

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Lapatinib Induces Autophagy, Apoptosis and Megakaryocytic Differentiation in Chronic Myelogenous Leukemia K562 Cells

Huey-Lan Huang, Yu-Chieh Chen, Yu-Chuen Huang, Kai-Chien Yang, Hsin yi Pan, Shou-Ping Shih, Yu-Jen Chen

published 22 Dec 2011

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A Two-Gene Signature, SKI and SLAMF1, Predicts Time-to-Treatment in Previously Untreated Patients with Chronic Lymphocytic Leukemia

Carmen D. Schweighofer, Kevin R. Coombes, Lynn L. Barron, Lixia Diao, Rachel J. Newman, Alessandra Ferrajoli, Susan O'Brien, William G. Wierda, Rajyalakshmi Luthra, L. Jeffrey Medeiros, Michael J. Keating, Lynne V. Abruzzo

published 14 Dec 2011

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Autophagy Inhibition Enhances Daunorubicin-Induced Apoptosis in K562 Cells

Weidong Han, Jie Sun, Lifeng Feng, KaiFeng Wang, Da Li, Qin Pan, Yan Chen, Wei Jin, Xian Wang, Hongming Pan, Hongchuan Jin

published 02 Dec 2011

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Runx1 Loss Minimally Impacts Long-Term Hematopoietic Stem Cells

Xiongwei Cai, Justin J. Gaudet, James K. Mangan, Michael J. Chen, Maria Elena De Obaldia, Zaw Oo, Patricia Ernst, Nancy A. Speck

published 01 Dec 2011

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Fitness Conferred by BCR-ABL Kinase Domain Mutations Determines the Risk of Pre-Existing Resistance in Chronic Myeloid Leukemia

Kevin Leder, Jasmine Foo, Brian Skaggs, Mercedes Gorre, Charles L. Sawyers, Franziska Michor

published 28 Nov 2011

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Transcriptional Repression of Cdc25B by IER5 Inhibits the Proliferation of Leukemic Progenitor Cells through NF-YB and p300 in Acute Myeloid Leukemia

Satoki Nakamura, Yasuyuki Nagata, Lin Tan, Tomonari Takemura, Kiyoshi Shibata, Michio Fujie, Shinya Fujisawa, Yasutaka Tanaka, Mitsuo Toda, Reiko Makita, Kenji Tsunekawa, Manabu Yamada, Mayumi Yamaoka, Junko Yamashita, Kazunori Ohnishi, Mitsuji Yamashita

published 23 Nov 2011

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Natural Killer Cell Mediated Missing-Self Recognition Can Protect Mice from Primary Chronic Myeloid Leukemia In Vivo

Mika Kijima, Noémie Gardiol, Werner Held

published 23 Nov 2011

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A Unique Role of GATA1s in Down Syndrome Acute Megakaryocytic Leukemia Biology and Therapy

Ana C. Xavier, Holly Edwards, Alan A. Dombkowski, Tugce B. Balci, Jason N. Berman, Graham Dellaire, Chengzhi Xie, Steven A. Buck, Larry H. Matherly, Yubin Ge, Jeffrey W. Taub

published 16 Nov 2011

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Long Circulating Lectin Conjugated Paclitaxel Loaded Magnetic Nanoparticles: A New Theranostic Avenue for Leukemia Therapy

Abhalaxmi Singh, Fahima Dilnawaz, Sanjeeb Kumar Sahoo

published 16 Nov 2011

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Identification of Hepatic Niche Harboring Human Acute Lymphoblastic Leukemic Cells via the SDF-1/CXCR4 Axis

Itaru Kato, Akira Niwa, Toshio Heike, Hisanori Fujino, Megumu K. Saito, Katsutsugu Umeda, Hidefumi Hiramatsu, Mamoru Ito, Makiko Morita, Yoko Nishinaka, Souichi Adachi, Fumihiko Ishikawa, Tatsutoshi Nakahata

published 01 Nov 2011

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