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Leukemia

Autophagy Inhibition Enhances Daunorubicin-Induced Apoptosis in K562 Cells

Weidong Han, Jie Sun, Lifeng Feng, KaiFeng Wang, Da Li, Qin Pan, Yan Chen, Wei Jin, Xian Wang, Hongming Pan, Hongchuan Jin

published 02 Dec 2011

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Runx1 Loss Minimally Impacts Long-Term Hematopoietic Stem Cells

Xiongwei Cai, Justin J. Gaudet, James K. Mangan, Michael J. Chen, Maria Elena De Obaldia, Zaw Oo, Patricia Ernst, Nancy A. Speck

published 01 Dec 2011

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Fitness Conferred by BCR-ABL Kinase Domain Mutations Determines the Risk of Pre-Existing Resistance in Chronic Myeloid Leukemia

Kevin Leder, Jasmine Foo, Brian Skaggs, Mercedes Gorre, Charles L. Sawyers, Franziska Michor

published 28 Nov 2011

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Transcriptional Repression of Cdc25B by IER5 Inhibits the Proliferation of Leukemic Progenitor Cells through NF-YB and p300 in Acute Myeloid Leukemia

Satoki Nakamura, Yasuyuki Nagata, Lin Tan, Tomonari Takemura, Kiyoshi Shibata, Michio Fujie, Shinya Fujisawa, Yasutaka Tanaka, Mitsuo Toda, Reiko Makita, Kenji Tsunekawa, Manabu Yamada, Mayumi Yamaoka, Junko Yamashita, Kazunori Ohnishi, Mitsuji Yamashita

published 23 Nov 2011

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Natural Killer Cell Mediated Missing-Self Recognition Can Protect Mice from Primary Chronic Myeloid Leukemia In Vivo

Mika Kijima, Noémie Gardiol, Werner Held

published 23 Nov 2011

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A Unique Role of GATA1s in Down Syndrome Acute Megakaryocytic Leukemia Biology and Therapy

Ana C. Xavier, Holly Edwards, Alan A. Dombkowski, Tugce B. Balci, Jason N. Berman, Graham Dellaire, Chengzhi Xie, Steven A. Buck, Larry H. Matherly, Yubin Ge, Jeffrey W. Taub

published 16 Nov 2011

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Long Circulating Lectin Conjugated Paclitaxel Loaded Magnetic Nanoparticles: A New Theranostic Avenue for Leukemia Therapy

Abhalaxmi Singh, Fahima Dilnawaz, Sanjeeb Kumar Sahoo

published 16 Nov 2011

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Identification of Hepatic Niche Harboring Human Acute Lymphoblastic Leukemic Cells via the SDF-1/CXCR4 Axis

Itaru Kato, Akira Niwa, Toshio Heike, Hisanori Fujino, Megumu K. Saito, Katsutsugu Umeda, Hidefumi Hiramatsu, Mamoru Ito, Makiko Morita, Yoko Nishinaka, Souichi Adachi, Fumihiko Ishikawa, Tatsutoshi Nakahata

published 01 Nov 2011

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Recurrent DNMT3A R882 Mutations in Chinese Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome

Jiang Lin, Dong-ming Yao, Jun Qian, Qin Chen, Wei Qian, Yun Li, Jing Yang, Cui-zhu Wang, Hai-yan Chai, Zhen Qian, Gao-fei Xiao, Wen-rong Xu

published 31 Oct 2011

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Halofuginone Has Anti-Proliferative Effects in Acute Promyelocytic Leukemia by Modulating the Transforming Growth Factor Beta Signaling Pathway

Lorena L. de Figueiredo-Pontes, Patricia A. Assis, Bárbara A. A. Santana-Lemos, Rafael H. Jácomo, Ana Sílvia G. Lima, Aglair B. Garcia, Carolina H. Thomé, Amélia G. Araújo, Rodrigo A. Panepucci, Marco A. Zago, Arnon Nagler, Roberto P. Falcão, Eduardo M. Rego

published 28 Oct 2011

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Functional Ramifications for the Loss of P-Selectin Expression on Hematopoietic and Leukemic Stem Cells

Con Sullivan, Yaoyu Chen, Yi Shan, Yiguo Hu, Cong Peng, Haojian Zhang, Linghong Kong, Shaoguang Li

published 24 Oct 2011

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Retroviral Integration Mutagenesis in Mice and Comparative Analysis in Human AML Identify Reduced PTP4A3 Expression as a Prognostic Indicator

Renée Beekman, Marijke Valkhof, Stefan J. Erkeland, Erdogan Taskesen, Veronika Rockova, Justine K. Peeters, Peter J. M. Valk, Bob Löwenberg, Ivo P. Touw

published 20 Oct 2011

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The Leukemia-Specific Fusion Gene ETV6/RUNX1 Perturbs Distinct Key Biological Functions Primarily by Gene Repression

Gerhard Fuka, Maximilian Kauer, Reinhard Kofler, Oskar A. Haas, Renate Panzer-Grümayer

published 20 Oct 2011

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